|
| 38047387 | Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies. | Circulation | 2024 |
| 37039676 | SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase. | | 2023 |
| 36409629 | Finnish-specific AKT2 gene variant leads to impaired insulin signalling in myotubes. | Journal of Molecular Endocrinology | 2023 |
| 37604891 | Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits. | Nat Commun | 2023 |
| 37647564 | Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits. | Diabetes | 2023 |
| 37795366 | Statins and risk of type 2 diabetes: mechanism and clinical implications. | | 2023 |
| 37560996 | Metabolites as Risk Factors for Diabetic Retinopathy in Patients with Type 2 Diabetes: a 12-year Follow-up Study. | | 2023 |
| 37961277 | Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits. | bioRxiv | 2023 |
| 37859345 | A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin. | | 2023 |
| 37034649 | Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. | medRxiv | 2023 |
| 36837886 | Plasma Metabolite Signatures in Male Carriers of Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease. | | 2023 |
| 36653033 | Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts. | BMJ | 2023 |
| 37280435 | Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood. | Diabetologia | 2023 |
| 36693378 | Loci for insulin processing and secretion provide insight into type 2 diabetes risk. | Am J Hum Genet | 2023 |
| 37120095 | Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models. | | 2023 |
| 36798216 | Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion. | medRxiv | 2023 |
| 37049626 | Lifestyle Intervention Guided by Group and Internet-Based Counseling in the T2D-GENE Trial Supports Its Applicability and Feasibility. | | 2023 |
| 37425837 | Metabolome-wide Mendelian randomization characterizes heterogeneous and shared causal effects of metabolites on human health. | medRxiv | 2023 |
| 37224770 | Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease. | EBioMedicine | 2023 |
| 34995504 | Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits. | Am J Hum Genet | 2022 |
| 35589964 | ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19. | Int J Obes (Lond) | 2022 |
| 36367234 | The FADS1 rs174550 Genotype Modifies the n-3 and n-6 PUFA and Lipid Mediator Responses to a High Alpha-Linolenic Acid and High Linoleic Acid Diets. | Molecular Nutrition and Food Research | 2022 |
| 36040803 | Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations. | JCI insight | 2022 |
| 35701670 | The FADS1 genotypes modify the effect of linoleic acid-enriched diet on adipose tissue inflammation via pro-inflammatory eicosanoid metabolism. | European Journal of Nutrition | 2022 |
| 35956377 | Genetics of Type 2 Diabetes: Past, Present, and Future. | Nutrients | 2022 |
| 35697829 | Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. | Commun Biol | 2022 |
| 35571963 | Effects of age, amyloid, sex, and <i>APOE</i> ε4 on the CSF proteome in normal cognition. | Alzheimers Dement (Amst) | 2022 |
| 36005625 | Metabolite Signature of Simvastatin Treatment Involves Multiple Metabolic Pathways. | Metabolites | 2022 |
| 35746833 | Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis. | Epigenetics | 2022 |
| 35629941 | Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study. | Metabolites | 2022 |
| 36333379 | Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. | Nat Commun | 2022 |
| 35551307 | Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. | Nat Genet | 2022 |
| 36198295 | Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells. | Cell Metab | 2022 |
| 35474963 | Multiparametric platform for profiling lipid trafficking in human leukocytes. | Cell Rep Methods | 2022 |
| 36055244 | Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk. | Am J Hum Genet | 2022 |
| 35981533 | Extent to which array genotyping and imputation with large reference panels approximate deep whole-genome sequencing. | Am J Hum Genet | 2022 |
| 37931405 | ERRATUM: Simvastatin profoundly impairs energy metabolism in primary human muscle cells. | | 2022 |
| 36557197 | Effects of Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment. | | 2022 |
| 36477530 | Genetic diversity fuels gene discovery for tobacco and alcohol use. | Nature | 2022 |
| 35050191 | Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men. | Metabolites | 2022 |
| 35063076 | Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance. | Cell | 2022 |
| 34718859 | FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study. | European Journal of Nutrition | 2022 |
| 34697471 | Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2. | Nature Metabolism | 2021 |
| 33594006 | Machine Learning Reveals Time-Varying Microbial Predictors with Complex Effects on Glucose Regulation. | mSystems | 2021 |
| 34233929 | Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study. | Diabetes | 2021 |
| 33798444 | Association of structural variation with cardiometabolic traits in Finns. | Am J Hum Genet | 2021 |
| 33686630 | Intranasal Fentanyl for Intervention-Associated Breakthrough Pain After Cardiac Surgery. | Clinical Pharmacokinetics | 2021 |
| 34108472 | Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. | Nat Commun | 2021 |
| 33888689 | Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. | Nat Commun | 2021 |
| 33462485 | Large-scale association analyses identify host factors influencing human gut microbiome composition. | Nat Genet | 2021 |