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Author Details

Kristin Baetz
Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary
1994
42
23
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36572187Pab1 acetylation at K131 decreases stress granule formation in Saccharomyces cerevisiae.J Biol Chem2023
35608294Fine-tuning acetyl-CoA carboxylase 1 activity through localization: functional genomics reveals a role for the lysine acetyltransferase NuA4 and sphingolipid metabolism in regulating Acc1 activity and localization.Genetics2022
33889823A yeast chemogenomic screen identifies pathways that modulate adipic acid toxicity.iScience2021
33590792Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells.Autophagy2021
33154962Multi-Faceted Systems Biology Approaches Present a Cellular Landscape of Phenolic Compound Inhibition in <i>Saccharomyces cerevisiae</i>.Front Bioeng Biotechnol2020
33253187Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology.PLoS Genet2020
30471359Yeast chemogenomic screen identifies distinct metabolic pathways required to tolerate exposure to phenolic fermentation inhibitors ferulic acid, 4-hydroxybenzoic acid and coniferyl aldehyde.Metab Eng2019
29396115A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems.Dev Cell2018
28714971Budding yeast Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregation.Nat Cell Biol2017
28231279Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.PLoS Genet2017
28455416NuA4 Lysine Acetyltransferase Complex Contributes to Phospholipid Homeostasis in <i>Saccharomyces cerevisiae</i>.G3 (Bethesda)2017
26757638A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction.Sci Rep2016
26512033Building a KATalogue of acetyllysine targeting and function.Brief Funct Genomics2016
24465216A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast.PLoS Genet2014
23572591mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases.Proc Natl Acad Sci U S A2013
22157760Iron-responsive transcription factor Aft1 interacts with kinetochore protein Iml3 and promotes pericentromeric cohesin.J Biol Chem2012
21347278Srf1 is a novel regulator of phospholipase D activity and is essential to buffer the toxic effects of C16:0 platelet activating factor.PLoS Genet2011
22384336Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae.G3 (Bethesda)2011
21984913Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4.PLoS One2011
21575565Chromosomal position effects are linked to sir2-mediated variation in transcriptional burst size.Biophys J2011
20024064Of proteins and DNA--proteomic role in the field of chromatin research.Mol Biosyst2010
21179020Defining the budding yeast chromatin-associated interactome.Mol Syst Biol2010
20439772Functional genomics analysis of the Saccharomyces cerevisiae iron responsive transcription factor Aft1 reveals iron-independent functions.Genetics2010
19106085A novel proteomics approach for the discovery of chromatin-associated protein networks.Mol Cell Proteomics2009
18212056Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity.Mol Cell Biol2008
16581777Methylation of histone H3 mediates the association of the NuA3 histone acetyltransferase with chromatin.Mol Cell Biol2006
16736013Predictable trends in protein noise.Nat Genet2006
16923967The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.Mol Cell Biol2006
16543219The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.Genes Dev2006
16582600Revealing hidden relationships among yeast genes involved in chromosome segregation using systematic synthetic lethal and synthetic dosage lethal screens.Cell Cycle2006
16172405Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation.Proc Natl Acad Sci U S A2005
15070751Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action.Proc Natl Acad Sci U S A2004
15353583Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4.Proc Natl Acad Sci U S A2004
14729968The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion.Mol Cell Biol2004
11533240Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4.Mol Cell Biol2001
10490612Regulation of cell cycle transcription factor Swi4 through auto-inhibition of DNA binding.Mol Cell Biol1999
9065400SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway.Science1997
8662078Mouse RSS spacer sequences affect the rate of V(D)J recombination.Immunogenetics1996
8939936Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase.J Biol Chem1996
7737276Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.Eur J Immunol1995
7751653Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis.J Immunol1995
8208601Conservation of sequence in recombination signal sequence spacers.Nucleic Acids Res1994
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Collaborators

University of Toronto
Co-authored papers 5
University of British Columbia
Co-authored papers 5
College Street, University of Toronto
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
Eastern Cereal and Oilseed Research Centre, Agriculture and Agri-Food Canada
Co-authored papers 2
EpiCypher Inc.
Co-authored papers 2
and Ottawa Institute of Systems Biology, University of Ottawa
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Showa University School of Medicine
Co-authored papers 2
Boston University School of Medicine, Boston University
Co-authored papers 2
State University of New York at Albany
Co-authored papers 1
Joan C. Edwards School of Medicine, Marshall University
Co-authored papers 1
University of Toronto
Co-authored papers 1
Concordia University
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
Columbia University Medical Center
Co-authored papers 1
Universite de Toulouse
Co-authored papers 1
Centre Hospitalier Universitaire (CHU) de Quebec-Universite Laval Research Center
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
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University of Toronto
Co-authored papers 1
Helmholtz Institute for Metabolic
Co-authored papers 1
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Luke's Medical Center Chicago
Co-authored papers 1
Toronto Metropolitan University
Co-authored papers 1
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BC Children's Hospital Research Institute, University of British Columbia
Co-authored papers 1
Stanford University
Co-authored papers 1