Author details

Full Name

Alexandra-ChloÃ© Villani

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37944567	Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma.	J Allergy Clin Immunol	2024
36657813	Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis.	J Immunother Cancer	2023
37632320	The evolving landscape of immune-related adverse events that follow immune checkpoint immunotherapy in cancer patients.		2023
37873428	Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches.		2023
37953958	Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following infection.		2023
37146132	A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma.	Sci Immunol	2023
36853705	Protocol for bulk RNA sequencing of enriched human neutrophils from whole blood and estimation of sample purity.	STAR Protoc	2023
35263562	Plasmacytoid dendritic cells: Welcome back to the DC fold.	Immunity	2022
36208629	Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients.	Cell Rep Med	2022
36324805	A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.	bioRxiv	2022
36526723	Germline variants associated with toxicity to immune checkpoint blockade.	Nat Med	2022
35143819	IL-32 Supports the Survival of Malignant T Cells in Cutaneous T-cell Lymphoma.		2022
34878969	Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19.	Am J Respir Crit Care Med	2022
34805429	Harnessing the Potential of Multiomics Studies for Precision Medicine in Infectious Disease.	Open Forum Infect Dis	2021
34020034	The positive effect of immune checkpoint inhibitor-induced thyroiditis on overall survival accounting for immortal time bias: a retrospective cohort study of 6596 patients.	Annals of Oncology	2021
33969320	Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions.	Cell Rep Med	2021
33479125	Developmental cell programs are co-opted in inflammatory skin disease.	Science	2021
34065016	The Known Unknowns of the Immune Response to .	Journal of Fungi	2021
34215691	Immune-related adverse events associated with immune checkpoint inhibitors: a call to action for collecting and sharing clinical trial and real-world data.	J Immunother Cancer	2021
34103408	Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.	Sci Transl Med	2021
33446482	Widespread haploid-biased gene expression enables sperm-level natural selection.	Science	2021
34196300	SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes.	J Clin Invest	2021
33655682	Temporal Trends and Outcomes Among Patients Admitted for Immune-Related Adverse Events: A Single-Center Retrospective Cohort Study from 2011 to 2018.	Oncologist	2021
33655257	SARS-CoV-2 Viremia is Associated with Distinct Proteomic Pathways and Predicts COVID-19 Outcomes.	medRxiv	2021
33655247	A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.	bioRxiv	2021
33915569	COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.	Nature	2021
33431694	Altered ratio of dendritic cell subsets in skin-draining lymph nodes promotes Th2-driven contact hypersensitivity.	Proceedings of the National Academy of Sciences of the United States of America	2021
34604114	Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures.	Front Cell Infect Microbiol	2021
34544895	Effect of a multidisciplinary Severe Immunotherapy Complications Service on outcomes for patients receiving immune checkpoint inhibitor therapy for cancer.	J Immunother Cancer	2021
34652962	Early cross-coronavirus reactive signatures of humoral immunity against COVID-19.	Sci Immunol	2021
34479924	Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR.	J Immunother Cancer	2021
31206576	IL-12 and Mucosal CD14+ Monocyte-Like Cells Induce IL-8 in Colonic Memory CD4+ T Cells of Patients With Ulcerative Colitis but not Crohn's Disease.		2020
32122464	SLAMF6â¿¿ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint.	Elife	2020
32341567	Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.	Nat Biotechnol	2020
32341560	Systematic comparison of single-cell and single-nucleus RNA-sequencing methods.	Nat Biotechnol	2020
31819171	Correction: Two distinct colonic CD14<sup>+</sup> subsets characterized by single-cell RNA profiling in Crohn's disease.	Mucosal Immunol	2020
33102962	Incidence and Clinical Features of Immune-Related Acute Kidney Injury in Patients Receiving Programmed Cell Death Ligand-1 Inhibitors.	Kidney Int Rep	2020
33190570	Decreased Absolute Lymphocyte Count and Increased Neutrophil/Lymphocyte Ratio With Immune Checkpoint Inhibitor-Associated Myocarditis.	Journal of the American Heart Association	2020
32690951	The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection.	Nat Immunol	2020
32908980	Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19.	bioRxiv	2020
33173871	Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients.	bioRxiv	2020
32719530	Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq.	Nat Methods	2020
31541232	Transcriptomic Analysis and High-dimensional Phenotypic Mapping of Mononuclear Phagocytes in Mesenteric Lymph Nodes Reveal Differences Between Ulcerative Colitis and Crohn's Disease.	J Crohns Colitis	2020
30670762	Two distinct colonic CD14<sup>+</sup> subsets characterized by single-cell RNA profiling in Crohn's disease.	Mucosal Immunol	2019
31597962	Decoding human fetal liver haematopoiesis.	Nature	2019
31672794	The Incidence, Causes, and Risk Factors of Acute Kidney Injury in Patients Receiving Immune Checkpoint Inhibitors.	Clinical journal of the American Society of Nephrology : CJASN	2019
30256981	Targeting individual cells by barcode in pooled sequence libraries.	Nucleic Acids Res	2019
30633907	Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.	Cell	2019
31092922	Targeting the CBM complex causes T cells to prime tumours for immune checkpoint therapy.	Nature	2019
31175469	Cardiotoxicity of Immune Checkpoint Inhibitors.	Current Treatment Options in Cardiovascular Medicine	2019