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Author Details

Matthew J Walter
Washington University School of Medicine in St. Louis
1994
103
44
PMIDPaper TitleJournal TitlePublished Year
36711871Genomic landscape of <i>TP53</i> -mutated myeloid malignancies.medRxiv2023
37597685Phase I-II Trial of Early Azacitidine after Matched Unrelated Donor Hematopoietic Cell Transplantation.Transplant Cell Ther2023
38090662Progressive, edematous plaques, mild pancytopenia, and inflammation.JAAD Case Rep2023
36947201Utility of targeted gene sequencing to differentiate myeloid malignancies from other cytopenic conditions.Blood Adv2023
37042968Statin use in myelodysplastic syndromes is associated with a better survival and decreased progression to leukemia.Blood Adv2023
37339484Genomic landscape of TP53-mutated myeloid malignancies.Blood Adv2023
37369199A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy.Mol Cell2023
36480766Clonal Hematopoiesis and Risk of Incident Lung Cancer.J Clin Oncol2023
36922625Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms.Leukemia2023
36853803Increased clonal hematopoiesis involving DNA damage response genes in patients undergoing lung transplantation.JCI Insight2023
35019859Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia.Blood Cancer Discov2022
35709710Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression.Blood Cancer Discov2022
35675516IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function.Blood2022
35367529Toll-like receptor and cytokine expression throughout the bone marrow differs between patients with low- and high-risk myelodysplastic syndromes.Exp Hematol2022
36130297Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.Blood2022
35895896Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.Blood2022
35041928Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence.J Mol Diagn2022
34873300Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells.Leukemia2022
33288274Corrigendum to "Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice" [Leuk. Res. 96C (2020) 106428].Leuk Res2021
33704937Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers.N Engl J Med2021
33689684A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.Cell Chem Biol2021
34469727Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice.Cell Rep2021
34546980U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice.J Clin Invest2021
34845035Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.Proc Natl Acad Sci U S A2021
34215620Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring <i>SF3B1</i> or <i>U2AF1</i> Mutations.Cancer Res2021
34341766Bam-readcount - rapid generation of basepair-resolution sequence metrics.ArXiv2021
32347921SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS.Blood2020
32739655Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice.Leuk Res2020
32430504Genetics of progression from MDS to secondary leukemia.Blood2020
30635634TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.Leukemia2019
31011167U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.Nat Cell Biol2019
31111762The National MDS Natural History Study: design of an integrated data and sample biorepository to promote research studies in myelodysplastic syndromes.Leuk Lymphoma2019
30846499Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling.Haematologica2019
29515031Subclones dominate at MDS progression following allogeneic hematopoietic cell transplant.JCI Insight2018
30054334Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes.Cancer Res2018
30207916Mutation Clearance after Transplantation for Myelodysplastic Syndrome.N Engl J Med2018
29959414Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS.Leukemia2018
30632131Identifying Molecular Markers of Relapse in Myelodysplastic Syndrome.Oncology (Williston Park)2018
30575467Mutation Clearance after Transplantation for Myelodysplastic Syndrome.N Engl J Med2018
30380364Immune Escape of Relapsed AML Cells after Allogeneic Transplantation.N Engl J Med2018
29617666Systematic Analysis of Splice-Site-Creating Mutations in Cancer.Cell Rep2018
29386642Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.Nat Commun2018
29358180Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the <i>NUP98-HOXD13</i> mouse model of MDS.Blood2018
29661788Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes.Blood2018
27940478Splicing factor gene mutations in hematologic malignancies.Blood2017
28082444Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.Blood2017
28215704CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.Cell2017
28178280Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells.PLoS One2017
27740633Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.Leukemia2017
28057668Antecedent CHIP in CML?Blood2017
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Collaborators

Timothy J Ley
Washington University School of Medicine
Co-authored papers 54
Daniel C Link
Washington University School of Medicine
Co-authored papers 43
Timothy A Graubert
Massachusetts General Hospital
Co-authored papers 43
John F DiPersio
Washington University School of Medicine
Co-authored papers 42
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 42
Peter Westervelt
Washington University School of Medicine
Co-authored papers 38
Christopher A Miller
Washington University School of Medicine
Co-authored papers 35
Sharon E Heath
Washington University School of Medicine.
Co-authored papers 34
Richard K Wilson
The Ohio State University
Co-authored papers 34
Elaine R Mardis
The Ohio State University
Co-authored papers 26
Michelle O'Laughlin
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 22
Jacqueline E Payton
Washington University School of Medicine.
Co-authored papers 21
Catrina Fronick
McDonnell Genome Institute, Washington University in St. Louis School of Medicine
Co-authored papers 20
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 20
Michael D McLellan
McDonnell Genome Institute, Washington University in St. Louis
Co-authored papers 18
Vincent Magrini
The Ohio State University
Co-authored papers 11
Daniel C Koboldt
Institute for Genomic Medicine, Nationwide Children's Hospital
Co-authored papers 11
David E Larson
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 11
David H Spencer
Washington University School of Medicine.
Co-authored papers 10
Lukas D Wartman
Washington University School of Medicine in St. Louis
Co-authored papers 8
Jeffery M Klco
St. Jude Children's Research Hospital
Co-authored papers 8
Tamara L Lamprecht
St. Jude Children's Research Hospital
Co-authored papers 8
Mark A Watson
Washington University School of Medicine
Co-authored papers 8
Rakesh Nagarajan
Current or past members of the College of American Pathologists
Co-authored papers 8
Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 7
Rhonda E Ries
Clinical Research Division, Fred Hutchinson Cancer Research Center
Co-authored papers 7
Brian S White
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Sean McGrath
Harvard T.H. Chan School of Public Health
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Kilannin Krysiak
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Release 1.2