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Author Details

Loyal A Goff
Johns Hopkins University School of Medicine
2004
69
33
PMIDPaper TitleJournal TitlePublished Year
37316665Psychedelics reopen the social reward learning critical period.Nature2023
38014224Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.bioRxiv2023
37585461<i>Ret</i> deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development.Proc Natl Acad Sci U S A2023
37989764Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS.Nat Protoc2023
37885016Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates.Genome Biol2023
37812717Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution.Proc Natl Acad Sci U S A2023
35263579Odorant-receptor-mediated regulation of chemosensory gene expression in the malaria mosquito Anopheles gambiae.Cell Rep2022
35463747Postnatal Smad3 Inactivation in Murine Smooth Muscle Cells Elicits a Temporally and Regionally Distinct Transcriptional Response.Front Cardiovasc Med2022
35998637The transcription factor Tbx5 regulates direction-selective retinal ganglion cell development and image stabilization.Curr Biol2022
36171283Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry.Nature2022
35882236Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.Immunity2022
35101061Universal prediction of cell-cycle position using transfer learning.Genome Biol2022
35148175Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea.Sci Adv2022
33446502An in vivo screen of noncoding loci reveals that <i>Daedalus</i> is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis.Proc Natl Acad Sci U S A2021
33600760Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species.Cell Syst2021
31581148Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis.J Clin Invest2020
33113347Parallel Social Information Processing Circuits Are Differentially Impacted in Autism.Neuron2020
33084572Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus.Elife2020
33277430Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells.Proc Natl Acad Sci U S A2020
32829096Screening non-MAPT genes of the Chr17q21 H1 haplotype in Parkinson's disease.Parkinsonism Relat Disord2020
32243843Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.Stem Cell Reports2020
32386599Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development.Dev Cell2020
32167521projectR: an R/Bioconductor package for transfer learning via PCA, NMF, correlation and clustering.Bioinformatics2020
31503409A screen of 1,049 schizophrenia and 30 Alzheimer's-associated variants for regulatory potential.Am J Med Genet B Neuropsychiatr Genet2020
31121116Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species.Cell Syst2019
31843893Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing.Proc Natl Acad Sci U S A2019
31465303Precocious neuronal differentiation and disrupted oxygen responses in Kabuki syndrome.JCI Insight2019
31337651Differential Variation Analysis Enables Detection of Tumor Heterogeneity Using Single-Cell RNA-Sequencing Data.Cancer Res2019
31128945Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.Neuron2019
30988181Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution.Proc Natl Acad Sci U S A2019
30866806Linear models enable powerful differential activity analysis in massively parallel reporter assays.BMC Genomics2019
29320739Variation in Activity State, Axonal Projection, and Position Define the Transcriptional Identity of Individual Neocortical Projection Neurons.Cell Rep2018
30188322Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells.Elife2018
30143323Enter the Matrix: Factorization Uncovers Knowledge from Omics.Trends Genet2018
29499164Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease.Am J Hum Genet2018
27999180A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.Proc Natl Acad Sci U S A2017
28821643Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease.J Neurosci2017
28930659Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.Immunity2017
26694805Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants.J Cyst Fibros2016
27801893The DPYSL2 gene connects mTOR and schizophrenia.Transl Psychiatry2016
27479747Investigating long noncoding RNAs using animal models.J Clin Invest2016
27296516Long noncoding RNAs: Central to nervous system development.Int J Dev Neurosci2016
27525555The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.Nature2016
25556833DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex.Neuron2015
26430155Linking RNA biology to lncRNAs.Genome Res2015
26034286Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain.Proc Natl Acad Sci U S A2015
24393486RNase-mediated protein footprint sequencing reveals protein-binding sites throughout the human transcriptome.Genome Biol2014
24997765Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.Nat Neurosci2014
24714615A positive feedback mechanism that regulates expression of miR-9 during neurogenesis.PLoS One2014
24463464Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre.Nat Struct Mol Biol2014
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Collaborators

Co-authored papers 19
Johns Hopkins School of Medicine
Co-authored papers 14
Johns Hopkins University School of Medicine
Co-authored papers 8
Johns Hopkins University School of Medicine
Co-authored papers 6
Massachusetts Institute of Technology
Co-authored papers 3
Johns Hopkins University School of Medicine.
Co-authored papers 3
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Johns Hopkins School of Medicine
Co-authored papers 3
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Co-authored papers 2
College of Basic Medical Sciences, Army Medical University
Co-authored papers 2
Co-authored papers 2
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Johns Hopkins University School of Medicine
Co-authored papers 2
Johns Hopkins School of Medicine
Co-authored papers 2
Yale University School of Medicine
Co-authored papers 1
The Salk Institute for Biological Studies
Co-authored papers 1
College of Basic Medicine, Army Medical University
Co-authored papers 1
Foundation Medicine Inc.
Co-authored papers 1
National Institute of Arthritis, National Institutes of Health
Co-authored papers 1
Whitehead Institute for Biomedical Research
Co-authored papers 1
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Johns Hopkins School of Medicine
Co-authored papers 1
Co-authored papers 1
The Salk Institute for Biological Studies
Co-authored papers 1
Vall d'Hebron Institute of Oncology (VHIO)
Co-authored papers 1
W.M. Keck Center for Collaborative Neuroscience, The State University of New Jersey
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1
Co-authored papers 1
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 1
University of Windsor
Co-authored papers 1