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Author Details

Argyris Politis
King's College London
2009
57
26
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36706021Chromatographic Phospholipid Trapping for Automated H/D Exchange Mass Spectrometry of Membrane Protein-Lipid Assemblies.Anal Chem2023
36976935Integrating Hydrogen Deuterium Exchange-Mass Spectrometry with Molecular Simulations Enables Quantification of the Conformational Populations of the Sugar Transporter XylE.J Am Chem Soc2023
36918534Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein.Nat Commun2023
36876893Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward.Essays Biochem2023
35313047Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage.Angew Chem Int Ed Engl2022
36357787Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor.Nat Chem2022
35981534A neutralizing epitope on the SD1 domain of SARS-CoV-2 spike targeted following infection and vaccination.Cell Rep2022
32722756Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry.Bioinformatics2021
34873050Linking function to global and local dynamics in an elevator-type transporter.Proc Natl Acad Sci U S A2021
33301120Integrative Mass Spectrometry-Based Approaches for Modeling Macromolecular Assemblies.Methods Mol Biol2021
32170968A glimpse into the molecular mechanism of integral membrane proteins through hydrogen-deuterium exchange mass spectrometry.Protein Sci2020
33268777Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter.Nat Commun2020
33067435Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry.Nat Commun2020
33149158Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB.Nat Commun2020
32597490Structural predictions of the functions of membrane proteins from HDX-MS.Biochem Soc Trans2020
32649184Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data.Anal Chem2020
32930597An Unusually Rapid Protein Backbone Modification Stabilizes the Essential Bacterial Enzyme MurA.Biochemistry2020
32667808Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology.Anal Chem2020
32141743Improving Peptide Fragmentation for Hydrogen-Deuterium Exchange Mass Spectrometry Using a Time-Dependent Collision Energy Calculator.J Am Soc Mass Spectrom2020
30338451POPPeT: a New Method to Predict the Protection Factor of Backbone Amide Hydrogens.J Am Soc Mass Spectrom2019
31611232Specific Residues in a Purine Transporter Are Critical for Dimerization, ER Exit, and Function.Genetics2019
31605097Integrating hydrogen-deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins.Nat Protoc2019
31290743HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon.Elife2019
31513392Protein-Lipid Interactions Stabilize the Oligomeric State of BOR1p from <i>Saccharomyces cerevisiae</i>.Anal Chem2019
30601115ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery.Elife2019
30649183Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry.Bioinformatics2019
29681524Structural Lipids Enable the Formation of Functional Oligomers of the Eukaryotic Purine Symporter UapA.Cell Chem Biol2018
30012626Specific cardiolipin-SecY interactions are required for proton-motive force stimulation of protein secretion.Proc Natl Acad Sci U S A2018
30297844Direct protein-lipid interactions shape the conformational landscape of secondary transporters.Nat Commun2018
30320553Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.Elife2018
30371663Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry.J Vis Exp2018
30452022Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs.Chem Commun (Camb)2018
30408305A Mass-Spectrometry-Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase.Angew Chem Int Ed Engl2018
28461040Structural characterisation of medically relevant protein assemblies by integrating mass spectrometry with computational modelling.J Proteomics2018
29049865Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions.Angew Chem Int Ed Engl2017
28208298Surface Accessibility and Dynamics of Macromolecular Assemblies Probed by Covalent Labeling Mass Spectrometry and Integrative Modeling.Anal Chem2017
29286378Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies.J Vis Exp2017
29149348Mechanistic insight into the assembly of the HerA-NurA helicase-nuclease DNA end resection complex.Nucleic Acids Res2017
27211036Hybrid Mass Spectrometry: Towards Characterization of Protein Conformational States.Trends Biochem Sci2016
26655720Uncovering the Early Assembly Mechanism for Amyloidogenic β2-Microglobulin Using Cross-linking and Native Mass Spectrometry.J Biol Chem2016
25544043Topological models of heteromeric protein assemblies from mass spectrometry: application to the yeast eIF3:eIF5 complex.Chem Biol2015
25755146Assembling the pieces of macromolecular complexes: Hybrid structural biology approaches.Proteomics2015
24509631A mass spectrometry-based hybrid method for structural modeling of protein complexes.Nat Methods2014
24746938Mass spectrometry defines the C-terminal dimerization domain and enables modeling of the structure of full-length OmpA.Structure2014
24557135Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility.Nat Chem2014
23583780Integrative modelling coupled with ion mobility mass spectrometry reveals structural features of the clamp loader in complex with single-stranded DNA binding protein.J Mol Biol2013
24119402Structure of the CRISPR interference complex CSM reveals key similarities with cascade.Mol Cell2013
23690617Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump.Proc Natl Acad Sci U S A2013
23756419Comparative cross-linking and mass spectrometry of an intact F-type ATPase suggest a role for phosphorylation.Nat Commun2013
22280183Charge-state dependent compaction and dissociation of protein complexes: insights from ion mobility and molecular dynamics.J Am Chem Soc2012
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Collaborators

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University of Oxford
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Co-authored papers 7
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University of Illinois at Urbana-Champaign
Co-authored papers 3
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Co-authored papers 2
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Max Planck Institute for Multidisciplinary Sciences
Co-authored papers 2
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ETH Zurich
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Anne-Claude Gavin
Co-authored papers 1
Mike O'Donnell
The Rockefeller University
Co-authored papers 1
Yuliya Gordiyenko
University of Oxford
Co-authored papers 1
Daniel Russel
University of California san francisco
Co-authored papers 1
Keren Lasker
The Scripps Research Institute
Co-authored papers 1
Release 1.2