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Author Details

Smita Patel
Institute for Neurodegenerative Diseases, University of California san francisco
2000
26
18
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32017806Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy.PLoS Pathog2020
28849371MSA prions exhibit remarkable stability and resistance to inactivation.Acta Neuropathol2018
29279394Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.Proc Natl Acad Sci U S A2018
29059326Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.JAMA Neurol2017
27440899Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.J Virol2016
27911827Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.Proc Natl Acad Sci U S A2016
27350609Towards authentic transgenic mouse models of heritable PrP prion diseases.Acta Neuropathol2016
26224882Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.J Pharmacol Exp Ther2015
26324905Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.Proc Natl Acad Sci U S A2015
26286986Propagation of prions causing synucleinopathies in cultured cells.Proc Natl Acad Sci U S A2015
26094969Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.Ann Neurol2015
24699458Evidence that bank vole PrP is a universal acceptor for prions.PLoS Pathog2014
22331873Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.Proc Natl Acad Sci U S A2012
22438549Identification of I137M and other mutations that modulate incubation periods for two human prion strains.J Virol2012
21727894Conserved properties of human and bovine prion strains on transmission to guinea pigs.Lab Invest2011
20695008Human prion strain selection in transgenic mice.Ann Neurol2010
16316656Lack of direct role of parkin in the steady-state level and aggregation of alpha-synuclein and the clearance of pre-formed aggregates.Exp Neurol2006
15976091Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.J Neurosci2005
15850587Distribution of brain atrophy in behavioral variant frontotemporal dementia.J Neurol Sci2005
15045511Survival advantage of cultured human vascular endothelial cells that lost chromosome 13.Chromosoma2004
14985429Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.J Neurosci2004
11904757Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation.Acta Neuropathol2002
12351643Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion.J Biol Chem2002
12468581Loss of chromosome 16 from renal epithelial cells in humans.Hypertension2002
12023418Patients with vascular dementia due to microvascular pathology have significant hippocampal neuronal loss.J Neurol Neurosurg Psychiatry2002
11035931Loss of chromosome 13 in cultured human vascular endothelial cells.Exp Cell Res2000
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Collaborators

Weill Institute for Neurosciences, University of California San Francisco
Co-authored papers 16
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Co-authored papers 13
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 11
Co-authored papers 7
University of Toronto
Co-authored papers 7
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Co-authored papers 5
Co-authored papers 3
Ageing Epidemiology Research Unit, School of Public Health, Imperial College London
Co-authored papers 3
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Co-authored papers 1
University of California los angeles
Co-authored papers 1
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
University of California davis
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1