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Author Details

David A Bushnell
Stanford University
1994
57
40
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37798444Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.Nat Biomed Eng2024
33411789The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.PLoS Pathog2021
33571424Mediator structure and conformation change.Mol Cell2021
33483974A Novel AKR1C3 Specific Prodrug TH3424 With Potent Antitumor Activity in Liver Cancer.Clin Pharmacol Ther2021
34062386Gold nanoparticles and tilt pairs to assess protein flexibility by cryo-electron microscopy.Ultramicroscopy2021
34202259Sub-3 ÿ Cryo-EM Structures of Necrosis Virus Particles via the Use of Multipurpose TEM with Electron Counting Camera.Int J Mol Sci2021
32811830A glycoprotein B-neutralizing antibody structure at 2.8⿿ÿ uncovers a critical domain for herpesvirus fusion initiation.Nat Commun2020
32859924Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 ÿ uncovers a critical domain for herpesvirus fusion initiation.Nat Commun2020
28635955Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography.Sci Rep2017
28300169Double-flow focused liquid injector for efficient serial femtosecond crystallography.Sci Rep2017
28514659The Intergenic Recombinant HLA-Bâ¿¿46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.Cell Rep2017
27610567Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.Cell2016
26189511Deconvolution method for specific and nonspecific binding of ligand to multiprotein complex by native mass spectrometry.Anal Chem2015
26483468Structure of an RNA polymerase II preinitiation complex.Proc Natl Acad Sci U S A2015
26402457Molecular architecture of the yeast Mediator complex.Elife2015
26311903Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.J Immunol2015
25146285Nanoparticle imaging. Electron microscopy of gold nanoparticles at atomic resolution.Science2014
23000482RNA polymerase II transcription: structure and mechanism.Biochim Biophys Acta2013
24072820Architecture of an RNA polymerase II transcription pre-initiation complex.Science2013
23633588AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery.Acta Crystallogr D Biol Crystallogr2013
22308316Subunit architecture of general transcription factor TFIIH.Proc Natl Acad Sci U S A2012
23071300Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II.Proc Natl Acad Sci U S A2012
21319754Synthesis and characterization of Au102(p-MBA)44 nanoparticles.J Am Chem Soc2011
22153066Lock and key to transcription: Ï¿-DNA interaction.Cell2011
21798951Initiation complex structure and promoter proofreading.Science2011
20099843Synthesis and bioconjugation of 2 and 3 nm-diameter gold nanoparticles.Bioconjug Chem2010
20798057RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription.Proc Natl Acad Sci U S A2010
19965383Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.Science2010
19478184Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.Science2009
19858347KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.J Exp Med2009
19458260Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.Proc Natl Acad Sci U S A2009
17947577Structure of a thiol monolayer-protected gold nanoparticle at 1.1 A resolution.Science2007
17129781Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis.Cell2006
15680971Structural basis of eukaryotic gene transcription.FEBS Lett2005
14963322Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.Science2004
15537538Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.Cell2004
15574497Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center.Proc Natl Acad Sci U S A2004
14963331Structural basis of transcription: separation of RNA from DNA by RNA polymerase II.Science2004
12746498Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.Proc Natl Acad Sci U S A2003
11805306Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.Proc Natl Acad Sci U S A2002
11342141Selenomethionine incorporation in Saccharomyces cerevisiae RNA polymerase II.Structure2001
11313498Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.Science2001
11313499Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.Science2001
10784442Architecture of RNA polymerase II and implications for the transcription mechanism.Science2000
10499797Yeast RNA polymerase II at 5 A resolution.Cell1999
9665838Repeated tertiary fold of RNA polymerase II and implications for DNA binding.J Mol Biol1998
9420330The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.Genes Dev1998
9545247Structure of wild-type yeast RNA polymerase II and location of Rpb4 and Rpb7.EMBO J1998
9278436The UL8 subunit of the heterotrimeric herpes simplex virus type 1 helicase-primase is required for the unwinding of single strand DNA-binding protein (ICP8)-coated DNA substrates.J Biol Chem1997
9237165Yeast RNA polymerase II transcription reconstituted with purified proteins.Methods1997
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Collaborators

Stanford University
Co-authored papers 48
College of Medical Veterinary and Life Sciences, University of Glasgow
Co-authored papers 8
University of Texas Southwestern Medical Center
Co-authored papers 7
Stanford University School of Medicine
Co-authored papers 5
Stanford University
Co-authored papers 4
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 4
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 4
Co-authored papers 4
Institute of Life Sciences, The Hebrew University
Co-authored papers 3
Stanford University
Co-authored papers 3
Co-authored papers 3
Stanford University
Co-authored papers 3
University of Toronto
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
California Institute of Technology, Brigham Young University
Co-authored papers 2
Panum Institute, University of Copenhagen
Co-authored papers 2
Cornell University
Co-authored papers 2
Yale University
Co-authored papers 1
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 1
CNRS UMR 5086 and Universite Claude Bernard Lyon 1
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 1
Institute of Genetics and Molecular Medicine, University of Edinburgh
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Lawrence Berkeley National Laboratory, University of California Santa Cruz
Co-authored papers 1
University of Oklahoma Health Sciences Center
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Stanford University
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Co-authored papers 1