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Author Details
Full Name
David A Bushnell
Affiliation
Stanford University
ORCID
Career Start Year
1994
Papers
57
H Index
40
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37798444
Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells.
Nat Biomed Eng
2024
33411789
The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion.
PLoS Pathog
2021
33571424
Mediator structure and conformation change.
Mol Cell
2021
33483974
A Novel AKR1C3 Specific Prodrug TH3424 With Potent Antitumor Activity in Liver Cancer.
Clin Pharmacol Ther
2021
34062386
Gold nanoparticles and tilt pairs to assess protein flexibility by cryo-electron microscopy.
Ultramicroscopy
2021
34202259
Sub-3 ÿ Cryo-EM Structures of Necrosis Virus Particles via the Use of Multipurpose TEM with Electron Counting Camera.
Int J Mol Sci
2021
32811830
A glycoprotein B-neutralizing antibody structure at 2.8⿿ÿ uncovers a critical domain for herpesvirus fusion initiation.
Nat Commun
2020
32859924
Publisher Correction: A glycoprotein B-neutralizing antibody structure at 2.8 ÿ uncovers a critical domain for herpesvirus fusion initiation.
Nat Commun
2020
28635955
Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep
2017
28300169
Double-flow focused liquid injector for efficient serial femtosecond crystallography.
Sci Rep
2017
28514659
The Intergenic Recombinant HLA-Bâ¿¿46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.
Cell Rep
2017
27610567
Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell
2016
26189511
Deconvolution method for specific and nonspecific binding of ligand to multiprotein complex by native mass spectrometry.
Anal Chem
2015
26483468
Structure of an RNA polymerase II preinitiation complex.
Proc Natl Acad Sci U S A
2015
26402457
Molecular architecture of the yeast Mediator complex.
Elife
2015
26311903
Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes.
J Immunol
2015
25146285
Nanoparticle imaging. Electron microscopy of gold nanoparticles at atomic resolution.
Science
2014
23000482
RNA polymerase II transcription: structure and mechanism.
Biochim Biophys Acta
2013
24072820
Architecture of an RNA polymerase II transcription pre-initiation complex.
Science
2013
23633588
AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery.
Acta Crystallogr D Biol Crystallogr
2013
22308316
Subunit architecture of general transcription factor TFIIH.
Proc Natl Acad Sci U S A
2012
23071300
Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II.
Proc Natl Acad Sci U S A
2012
21319754
Synthesis and characterization of Au102(p-MBA)44 nanoparticles.
J Am Chem Soc
2011
22153066
Lock and key to transcription: Ï¿-DNA interaction.
Cell
2011
21798951
Initiation complex structure and promoter proofreading.
Science
2011
20099843
Synthesis and bioconjugation of 2 and 3 nm-diameter gold nanoparticles.
Bioconjug Chem
2010
20798057
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription.
Proc Natl Acad Sci U S A
2010
19965383
Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism.
Science
2010
19478184
Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science
2009
19858347
KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
J Exp Med
2009
19458260
Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc Natl Acad Sci U S A
2009
17947577
Structure of a thiol monolayer-protected gold nanoparticle at 1.1 A resolution.
Science
2007
17129781
Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis.
Cell
2006
15680971
Structural basis of eukaryotic gene transcription.
FEBS Lett
2005
14963322
Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.
Science
2004
15537538
Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell
2004
15574497
Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center.
Proc Natl Acad Sci U S A
2004
14963331
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II.
Science
2004
12746498
Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription.
Proc Natl Acad Sci U S A
2003
11805306
Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.
Proc Natl Acad Sci U S A
2002
11342141
Selenomethionine incorporation in Saccharomyces cerevisiae RNA polymerase II.
Structure
2001
11313498
Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science
2001
11313499
Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science
2001
10784442
Architecture of RNA polymerase II and implications for the transcription mechanism.
Science
2000
10499797
Yeast RNA polymerase II at 5 A resolution.
Cell
1999
9665838
Repeated tertiary fold of RNA polymerase II and implications for DNA binding.
J Mol Biol
1998
9420330
The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.
Genes Dev
1998
9545247
Structure of wild-type yeast RNA polymerase II and location of Rpb4 and Rpb7.
EMBO J
1998
9278436
The UL8 subunit of the heterotrimeric herpes simplex virus type 1 helicase-primase is required for the unwinding of single strand DNA-binding protein (ICP8)-coated DNA substrates.
J Biol Chem
1997
9237165
Yeast RNA polymerase II transcription reconstituted with purified proteins.
Methods
1997
1 - 50 of 57
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