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Author Details

Michael C Thompson
University of California
2011
28
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37398339Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.bioRxiv2024
37723259Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography.Nat Chem2023
37748829Combining temperature perturbations with X-ray crystallography to study dynamic macromolecules: A thorough discussion of experimental methods.Methods Enzymol2023
37645800Changes in an Enzyme Ensemble During Catalysis Observed by High Resolution XFEL Crystallography.bioRxiv2023
35169801The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature.bioRxiv2022
35622909The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature.Sci Adv2022
35254891Accurate positioning of functional residues with robotics-inspired computational protein design.Proc Natl Acad Sci U S A2022
33853786Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.Sci Adv2021
32148858Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.IUCrJ2020
33154106An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.Science2020
32968058Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico.Nat Commun2020
32855341Expanding the space of protein geometries by computational design of de novo fold families.Science2020
32676184Advances in methods for atomic resolution macromolecular structure determination.F1000Res2020
32504875BATMAN: Fast and Accurate Integration of Single-Cell RNA-Seq Datasets via Minimum-Weight Matching.iScience2020
31527847Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme.Nat Chem2019
31754004Computational design of a modular protein sense-response system.Science2019
31801874Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.Proc Natl Acad Sci U S A2019
29717712Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism.Acta Crystallogr D Struct Biol2018
28573574Identifying and Overcoming Crystal Pathologies: Disorder and Twinning.Methods Mol Biol2017
28416112Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.Structure2017
28759216Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases.J Am Chem Soc2017
26988700Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.Chem Commun (Camb)2016
25752492An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein.Protein Sci2015
26422513Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.Elife2015
24419393A challenging interpretation of a hexagonally layered protein structure.Acta Crystallogr D Biol Crystallogr2014
25484204Structure of a bacterial microcompartment shell protein bound to a cobalamin cofactor.Acta Crystallogr F Struct Biol Commun2014
25102080Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein.J Mol Biol2014
21315581The protein shells of bacterial microcompartment organelles.Curr Opin Struct Biol2011
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Collaborators

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Co-authored papers 5
Lawrence Berkeley National Laboratory
Co-authored papers 5
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Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 3
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
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UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Co-authored papers 1
California Institute of Technology
Co-authored papers 1
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Columbia University
Co-authored papers 1
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Howard Hughes Medical Institute, University of California at San Francisco
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Fred Hutchinson Cancer Center
Co-authored papers 1
Howard Hughes Medical Institute, University of California at San Francisco
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Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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