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Author Details

Danilo A Tagle
1986
116
54
PMIDPaper TitleJournal TitlePublished Year
34380142Microphysiological Systems: Stakeholder Challenges to Adoption in Drug Development.Cells Tissues Organs2022
36177947Engineering multicellular living systems-a Keystone Symposia report.Ann N Y Acad Sci2022
35632824Pivoting Novel Exosome-Based Technologies for the Detection of SARS-CoV-2.Viruses2022
34783606Emerging technologies and their impact on regulatory science.Exp Biol Med (Maywood)2022
32913334Organs-on-chips: into the next decade.Nat Rev Drug Discov2021
33899539Microphysiological systems: What it takes for community adoption.Experimental Biology and Medicine2021
31166829Improved Ocular Tissue Models and Eye-On-A-Chip Technologies Will Facilitate Ophthalmic Drug Development.Journal of Ocular Pharmacology and Therapeutics2020
32113184Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug developmentALTEX2020
32397761Tackling rare diseases: Clinical trials on chips.Experimental Biology and Medicine2020
32285363Organs-on-a-Chip.Advances in Experimental Medicine and Biology2020
33490601Extracellular RNAs as potential biomarkers for cancer.Journal of Cancer Metastasis and Treatment2020
33501158Exploring Novel Biologically-Relevant Chemical Space Through Artificial Intelligence: The NCATS ASPIRE Program.Front Robot AI2020
30710133Mapping biologically active chemical space to accelerate drug discovery.Nat Rev Drug Discov2019
31622895The NIH microphysiological systems program: developing in vitro tools for safety and efficacy in drug development.Current Opinion in Pharmacology2019
29712768Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III".Molecular and Cellular Biology2018
28078768Microphysiological Systems ("Organs-on-Chips") for Drug Efficacy and Toxicity Testing.Clinical and Translational Science2017
28343437Organs-on-chips: Progress, challenges, and future directions.Experimental Biology and Medicine2017
28622731Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective.Experimental Biology and Medicine2017
28795174Tissue chips - innovative tools for drug development and disease modeling.Lab on a Chip2017
29214585Microphysiological Systems (Tissue Chips) and their Utility for Rare Disease Research.Advances in Experimental Medicine and Biology2017
27554434Good Cell Culture Practice for stem cells and stem-cell-derived models.ALTEX2017
27775817Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury.Hepatology2017
27904714Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public-private partnerships.Computational and Structural Biotechnology Journal2016
28626620Tissue Chips to aid drug development and modeling for rare diseases.Expert Opinion on Orphan Drugs2016
27180100Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.ALTEX2016
27682891Diagnostic potential of extracellular RNA from biofluids.Expert Review of Molecular Diagnostics2016
26320938The NIH Extracellular RNA Communication Consortium.Journal of Extracellular Vesicles2015
25654329Perspectives on best practices for gene therapy programs.Human Gene Therapy2015
24962171Organs-on-chips (microphysiological systems): tools to expedite efficacy and toxicity testing in human tissue.Experimental Biology and Medicine2014
24911489Expanding rare disease drug trials based on shared molecular etiology.Nat Biotechnol2014
24667081Phenylketonuria Scientific Review Conference: state of the science and future research needs.Mol Genet Metab2014
25061900Developing microphysiological systems for use as regulatory tools--challenges and opportunities.ALTEX2014
24565163The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline.Stem Cell Research and Therapy2013
22053864Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam Principles).J Proteome Res2012
22583803The human proteome - a scientific opportunity for transforming diagnostics, therapeutics, and healthcare.Clin Proteomics2012
22424650An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project.Ann Emerg Med2012
22710757Sham neurosurgical procedures in clinical trials for neurodegenerative diseases: scientific and ethical considerations.Lancet Neurol2012
22069307Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles).Proteomics2012
22213554Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles).Proteomics Clin Appl2011
21176882Research challenges in central nervous system manifestations of inborn errors of metabolism.Mol Genet Metab2011
21257639Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.Hum Mol Genet2011
20977429Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV.Bioscience Reports2011
22052993Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam Principles).Mol Cell Proteomics2011
19826765Structure, expression, and function of kynurenine aminotransferases in human and rodent brains.Cellular and Molecular Life Sciences2010
20482848Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases.BMC Biochemistry2010
19338303Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K.Journal of Medicinal Chemistry2009
19029248Biochemical and structural properties of mouse kynurenine aminotransferase III.Molecular and Cellular Biology2009
18620547Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II.Bioscience Reports2008
16376499Characterization of kynurenine aminotransferase III, a novel member of a phylogenetically conserved KAT family.Gene2006
16099455Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease.Experimental Neurology2006
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