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Author Details

Yoav Peleg
Weizmann Institute of Science
1990
81
27
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36808692Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.FEBS J2023
37917580A concise guide to choosing suitable gene expression systems for recombinant protein production.STAR Protoc2023
37561584Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.J Clin Invest2023
34826176De novo developed protein binders mimicking Interferon lambda signaling.FEBS J2022
35710843Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels.Nat Struct Mol Biol2022
35727449Application of Restriction Free (RF) Cloning in Circular Permutation.Methods Mol Biol2022
35359497The identification and characterization of an oxalyl-CoA synthetase from grass pea (<i>Lathyrus sativus</i> L.).RSC Chem Biol2022
36279206Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.Biol Chem2022
35102291Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.Nat Biotechnol2022
35137169Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds.Nucleic Acids Res2022
34337607Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction.JACS Au2021
33863891DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.Nat Commun2021
33781758Community-Wide Experimental Evaluation of the PROSS Stability-Design Method.J Mol Biol2021
33858992Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.Science2021
34381047Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.Nat Commun2021
34609866Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes.J Am Chem Soc2021
34717958Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma.J Biol Chem2021
31549491New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.FEBS J2020
32817524Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.Proc Natl Acad Sci U S A2020
32500941Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.EMBO J2020
31152679Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.FEBS J2019
29319799Facilitating circular permutation using Restriction Free (RF) cloning.Protein Eng Des Sel2018
30250274Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3⿿ÿ resolution.Nat Commun2018
30088929Manipulating the Folding Landscape of a Multidomain Protein.J Phys Chem B2018
30248156Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli.PLoS One2018
30534605Rapid characterization of secreted recombinant proteins by native mass spectrometry.Commun Biol2018
28470597Harnessing the Profinity eXactâ¿¢ System for Expression and Purification of Heterologous Proteins in E. coli.Methods Mol Biol2017
28099413Communication between viruses guides lysis-lysogeny decisions.Nature2017
27098554Fine Tuning of Chlorophyll Spectra by Protein-Induced Ring Deformation.Angew Chem Int Ed Engl2016
27982031Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo.Sci Rep2016
27022017Do Src Kinase and Caveolin Interact Directly with Na,K-ATPase?J Biol Chem2016
25605918Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast.Proc Natl Acad Sci U S A2015
26429909Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.J Biol Chem2015
25930950A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.Chembiochem2015
25785780AcpM, the meromycolate extension acyl carrier protein of Mycobacterium tuberculosis, is activated by the 4'-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.Biochemistry2015
25795784The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.J Biol Chem2015
24395358Application of the Restriction-Free (RF) cloning for multicomponents assembly.Methods Mol Biol2014
24927597Integration of bacterial lytic polysaccharide monooxygenases into designer cellulosomes promotes enhanced cellulose degradation.Proc Natl Acad Sci U S A2014
24395359A single-tube assembly of DNA using the transfer-PCR (TPCR) platform.Methods Mol Biol2014
23478446Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning.Mol Cell2013
24341331A synthetic biology approach for evaluating the functional contribution of designer cellulosome components to deconstruction of cellulosic substrates.Biotechnol Biofuels2013
21964790Recombinant protein expression in the baculovirus-infected insect cell system.Methods Mol Biol2012
22194329Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations.Acta Crystallogr D Biol Crystallogr2012
21964789Resolving bottlenecks for recombinant protein expression in E. coli.Methods Mol Biol2012
21228272FXYD proteins stabilize Na,K-ATPase: amplification of specific phosphatidylserine-protein interactions.J Biol Chem2011
21515384Transfer-PCR (TPCR): a highway for DNA cloning and protein engineering.J Struct Biol2011
21738225GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.EMBO Rep2011
21382497Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study.J Struct Biol2011
20600952Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression.J Struct Biol2010
18938249Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: over-expression, purification and biophysical characterization.Protein Expr Purif2009
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Collaborators

Weizmann Institute of Science
Co-authored papers 21
Weizmann Institute of Science
Co-authored papers 19
Weizmann Institute of Science
Co-authored papers 15
Weizmann Institute of Science
Co-authored papers 12
Co-authored papers 6
Weizmann Institute of Science
Co-authored papers 3
CNRS, Aix-Marseille Universite
Co-authored papers 3
Weizmann Institute of Science
Co-authored papers 3
University of Oxford
Co-authored papers 3
Helmholtz Centre for Infection Research
Co-authored papers 3
Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 3
The Weizmann Institute of Science
Co-authored papers 2
University of Oxford
Co-authored papers 2
Aix Marseille University and CNRS
Co-authored papers 2
Co-authored papers 2
King's College London BHF Centre for Research Excellence
Co-authored papers 2
the Francis Crick Institute
Co-authored papers 1
Robert Wood Johnson Medical School, Rutgers University
Co-authored papers 1
Rensselaer Polytechnic Institute
Co-authored papers 1
Co-authored papers 1
University of Oxford
Co-authored papers 1
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers 1
Nankai University
Co-authored papers 1
University of California Berkeley
Co-authored papers 1
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 1
Co-authored papers 1
Brookhaven National Laboratory
Co-authored papers 1
Karolinska Institutet, BioClinicum J6
Co-authored papers 1
Los Alamos National Laboratory
Co-authored papers 1
University of Science & Technology of China
Co-authored papers 1