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Author Details

David S Ziegler
2001
126
29
PMIDPaper TitleJournal TitlePublished Year
37823831Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.Cancer Discov2024
37480151Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer.Cell Biosci2023
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
37726477Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives.Br J Cancer2023
37683275Microtubule-Targeting Combined with HDAC Inhibition Is a Novel Therapeutic Strategy for Diffuse Intrinsic Pontine Gliomas.2023
37075810LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.Neuro Oncol2023
37013636A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.Genome Med2023
36882456Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes.Sci Rep2023
37382186Parents' expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial.Cancer2023
37124503BRAF-mediated brain tumors in adults and children: A review and the Australian and New Zealand experience.Front Oncol2023
37001527Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities.Cancer Cell2023
37376781Parents' and adolescents' perspectives and understanding of information about childhood cancer precision medicine.Cancer2023
36937401<i>In vivo</i> loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma.Front Oncol2023
37178647Afatinib in paediatric patients with recurrent/refractory ErbB-dysregulated tumours: Results of a phase I/expansion trial.Eur J Cancer2023
37523146High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.Cancer Res2023
37517472Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors: The AIM BRAIN Project: An Australian and New Zealand Children's Haematology/Oncology Group Study.J Mol Diagn2023
37511646Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.J Pers Med2023
35148393Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry.Neuro Oncol2022
36358729Quality of Life (QoL) of Children and Adolescents Participating in a Precision Medicine Trial for High-Risk Childhood Cancer.Cancers2022
36167468GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma.Journal for ImmunoTherapy of Cancer2022
35832071Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy.Theranostics2022
36013276What's in a Name? Parents' and Healthcare Professionals' Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes.J Pers Med2022
36215217Phase 1b study of carfilzomib with induction chemotherapy in pediatric relapsed/refractory acute lymphoblastic leukemia.Pediatric Blood and Cancer2022
35999452Parents' understanding of genome and exome sequencing for pediatric health conditions: a systematic review.Eur J Hum Genet2022
35552452Characteristics of children ⿤36 months of age with DIPG: A report from the international DIPG registry.Neuro Oncol2022
35802025FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits.Cancer Res2022
35989458Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR).Pediatr Blood Cancer2022
36582791Resistance mechanisms in BRAF paediatric high-grade glioma and current therapeutic approaches.2022
34166569Barriers and potential solutions to international collaboration in neuro-oncology clinical trials: Challenges from the Australian perspective.Asia-Pacific Journal of Clinical Oncology2022
34992263Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.Nat Med2022
34850167Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors.Neuro Oncol2022
34668975Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.Neuro Oncol2022
35180323Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.Am J Hematol2022
34944870Therapeutic Targets in Diffuse Midline Gliomas-An Emerging Landscape.Cancers2021
32267508Diagnostic Yield of Initial and Consecutive Blood Cultures in Children With Cancer and Febrile Neutropenia.Journal of the Pediatric Infectious Diseases Society2021
33486006Frontiers in the treatment of glioblastoma: Past, present and emerging.Advanced Drug Delivery Reviews2021
33805713Doxorubicin-Loaded Gold Nanoarchitectures as a Therapeutic Strategy against Diffuse Intrinsic Pontine Glioma.Cancers2021
33852836Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.Cell Rep2021
33580196Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor.NPJ Precis Oncol2021
33579942Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.Nat Commun2021
33890721Copper: An Intracellular Achilles' Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics.ChemMedChem2021
33996584Malignant Melanoma in Children and Adolescents Treated in Pediatric Oncology Centers: An Australian and New Zealand Children's Oncology Group (ANZCHOG) Study.Front Oncol2021
33994371Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Clin Cancer Res2021
33945292Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance.J Clin Oncol2021
34298664Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.Cancers (Basel)2021
33918978A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.Cancers (Basel)2021
33355208DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.Cancer Discov2021
32971146Gastrointestinal Hemorrhage: A Manifestation of the Telomere Biology Disorders.J Pediatr2021
34572932Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.Cancers (Basel)2021
34458732Parents' experiences of postmortem tumor donation for high-grade gliomas: benefits and suggested improvements.Neuro-Oncology Advances2021
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Children's Cancer Institute, Lowy Cancer Research Centre
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The Hospital for Sick Children
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Lowy Cancer Research Centre, Children's Cancer Institute
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Perth Children's Hospital
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Brain Tumor Institute, Children's National Hospital
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McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
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Fondazione IRCCS Istituto Nazionale dei Tumori
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Perelman School of Medicine, University of Pennsylvania
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Hospital for Sick Children
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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and Center for Bioethics, Harvard Medical School
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Broad Institute of the Massachusetts Institute of Technology and Harvard
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Cancer and Blood Disease Institute, Children's Hospital Los Angeles
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