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Author Details
Full Name
Patrick Van Roey
Affiliation
Center for Medical Sciences
ORCID
Career Start Year
1981
Papers
47
H Index
26
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
28381603
Comprehensive Whole-Genome Sequencing and Reporting of Drug Resistance Profiles on Clinical Cases of Mycobacterium tuberculosis in New York State.
J Clin Microbiol
2017
26538069
Clinical Sensitivity of Cystic Fibrosis Mutation Panels in a Diverse Population.
Hum Mutat
2016
24408076
Green-lighting green fluorescent protein: faster and more efficient folding by eliminating a cis-trans peptide isomerization event.
Protein Sci
2014
23423655
A conserved threonine spring-loads precursor for intein splicing.
Protein Sci
2013
21460844
Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications.
Nat Struct Mol Biol
2011
20304107
Restricted domain mobility in the Candida albicans Ess1 prolyl isomerase.
Biochim Biophys Acta
2010
19744499
Selection and structure of hyperactive inteins: peripheral changes relayed to the catalytic center.
J Mol Biol
2009
19636882
1H, 13C, and 15N NMR assignments of an engineered intein based on Mycobacterium tuberculosis RecA.
Biomol NMR Assign
2008
17085503
Mechanism for intein C-terminal cleavage: a proposal from quantum mechanical calculations.
Biophys J
2007
17254599
Crystallographic and mutational studies of Mycobacterium tuberculosis recA mini-inteins suggest a pivotal role for a highly conserved aspartate residue.
J Mol Biol
2007
15835905
The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility.
Biochemistry
2005
16288917
Minimization and stabilization of the Mycobacterium tuberculosis recA intein.
J Mol Biol
2005
15361856
Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor.
Nat Struct Mol Biol
2004
15504034
Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.
Biochemistry
2004
12809609
Study of the structural dynamics of the E coli 70S ribosome using real-space refinement.
Cell
2003
12932195
Family 18 chitinase-oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A.
Biochem J
2003
12077294
Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI.
Proc Natl Acad Sci U S A
2002
12379841
Catalytic domain structure and hypothesis for function of GIY-YIG intron endonuclease I-TevI.
Nat Struct Biol
2002
11953431
Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate.
J Biol Chem
2002
11447104
Intertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate.
EMBO J
2001
11316879
Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci
2001
11222739
Three-dimensional structure of human follicle-stimulating hormone.
Mol Endocrinol
2001
11750726
Structural biology of human follitropin and its receptor.
Arch Med Res
2001
10891067
Structural basis for the substrate specificity of endo-beta-N-acetylglucosaminidase F(3).
Biochemistry
2000
10595536
Mutations of endo-beta-N-acetylglucosaminidase H active site residueAs sp130 anG glu132: activities and conformations.
Protein Sci
1999
10047486
Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI.
J Mol Biol
1999
10091656
Crystal structure of thymidylate synthase A from Bacillus subtilis.
Protein Sci
1999
9541410
Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum.
Protein Sci
1998
10089530
Crystallization and preliminary crystallographic analysis of the archaeal intron-encoded endonuclease I-DmoI.
Acta Crystallogr D Biol Crystallogr
1998
7493989
Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F.
J Biol Chem
1995
7663942
Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition.
Structure
1995
7918386
Crystal structure of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F at 2.2-A resolution.
Biochemistry
1994
8133514
Crystallization and preliminary crystallographic analysis of two endo-beta-N-acetylglucosaminidases, endo H and endo F1.
J Mol Biol
1994
8057383
Crystallization and preliminary crystallographic analysis of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase PNGase F.
J Mol Biol
1994
7947807
Crystal structure of endo-beta-N-acetylglucosaminidase F1, an alpha/beta-barrel enzyme adapted for a complex substrate.
Biochemistry
1994
1597854
Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.
J Med Chem
1992
1669441
Structure-activity studies of non-steroidal aromatase inhibitors: the crystal and molecular structures of CGS 16949A and CGS 18320B.
J Enzyme Inhib
1991
1863426
Structure of (+/-)-aminoglutethimide.
Acta Crystallogr C
1991
1930813
Structure of cis-1-([4-(1-imidazolylmethyl)cyclohexyl]methyl)imidazole- succinic acid complex.
Acta Crystallogr C
1991
1706572
Correlation of molecular conformation and activity of reverse transcriptase inhibitors.
Ann N Y Acad Sci
1990
2726758
Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.
Proc Natl Acad Sci U S A
1989
2771945
Crystal structure analysis of auromomycin apoprotein (macromomycin) shows importance of protein side chains to chromophore binding selectivity.
Proc Natl Acad Sci U S A
1989
3271082
Structure of 4-methylumbelliferyl-beta-D-glucopyranoside.
Acta Crystallogr C
1988
3172772
Crystallization of prostatic binding protein.
J Steroid Biochem
1988
6654587
Crystal and molecular structure of tert.-butyloxycarbonyl-L-prolyl-alpha-aminoisobutyryl-L-alanyl-alpha- aminoisobutyrate methyl ester.
Int J Pept Protein Res
1983
7118420
Crystal and molecular structure of tert.-butyloxycarbonyl-L-hydroxy-prolyl-alpha-aminoisobutyryl-alpha-aminoisobutyryl-L-phenylalaninol.
Int J Pept Protein Res
1982
7338912
Preliminary crystallographic study of macromomycin.
J Mol Biol
1981
1 - 47 of 47
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row(s) 1 - 30 of 30
Collaborators
Peter Kuhn
University of Tubingen
Co-authored papers
3
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers
1
Haixiao Gao
Howard Hughes Medical Institute, Inc. at the Wadsworth Center
Co-authored papers
1
Michael S Chapman
University of Missouri
Co-authored papers
1
Andrei A Korostelev
RNA Therapeutics Institute, University of Massachusetts Chan Medical School
Co-authored papers
1
Scott M Stagg
Florida State University
Co-authored papers
1
Narayanan Eswar
University of California at San Francisco
Co-authored papers
1
Rajendra K Agrawal
School of Public Health, University at Albany
Co-authored papers
1
Joachim Frank
Columbia University
Co-authored papers
1
Stephen C Harvey
University of Pennsylvania
Co-authored papers
1
Jayati Sengupta
Institute of Child Health
Co-authored papers
1
Mikel Valle
Center for Cooperative Research in Biosciences (CIC bioGUNE)
Co-authored papers
1
Meyer Kattan
Columbia University Medical Center
Co-authored papers
1
1 - 13