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Author Details

Patrick Van Roey
Center for Medical Sciences
1981
47
26
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
28381603Comprehensive Whole-Genome Sequencing and Reporting of Drug Resistance Profiles on Clinical Cases of Mycobacterium tuberculosis in New York State.J Clin Microbiol2017
26538069Clinical Sensitivity of Cystic Fibrosis Mutation Panels in a Diverse Population.Hum Mutat2016
24408076Green-lighting green fluorescent protein: faster and more efficient folding by eliminating a cis-trans peptide isomerization event.Protein Sci2014
23423655A conserved threonine spring-loads precursor for intein splicing.Protein Sci2013
21460844Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications.Nat Struct Mol Biol2011
20304107Restricted domain mobility in the Candida albicans Ess1 prolyl isomerase.Biochim Biophys Acta2010
19744499Selection and structure of hyperactive inteins: peripheral changes relayed to the catalytic center.J Mol Biol2009
196368821H, 13C, and 15N NMR assignments of an engineered intein based on Mycobacterium tuberculosis RecA.Biomol NMR Assign2008
17085503Mechanism for intein C-terminal cleavage: a proposal from quantum mechanical calculations.Biophys J2007
17254599Crystallographic and mutational studies of Mycobacterium tuberculosis recA mini-inteins suggest a pivotal role for a highly conserved aspartate residue.J Mol Biol2007
15835905The structure of the Candida albicans Ess1 prolyl isomerase reveals a well-ordered linker that restricts domain mobility.Biochemistry2005
16288917Minimization and stabilization of the Mycobacterium tuberculosis recA intein.J Mol Biol2005
15361856Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor.Nat Struct Mol Biol2004
15504034Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase.Biochemistry2004
12809609Study of the structural dynamics of the E coli 70S ribosome using real-space refinement.Cell2003
12932195Family 18 chitinase-oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A.Biochem J2003
12077294Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI.Proc Natl Acad Sci U S A2002
12379841Catalytic domain structure and hypothesis for function of GIY-YIG intron endonuclease I-TevI.Nat Struct Biol2002
11953431Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate.J Biol Chem2002
11447104Intertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate.EMBO J2001
11316879Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.Protein Sci2001
11222739Three-dimensional structure of human follicle-stimulating hormone.Mol Endocrinol2001
11750726Structural biology of human follitropin and its receptor.Arch Med Res2001
10891067Structural basis for the substrate specificity of endo-beta-N-acetylglucosaminidase F(3).Biochemistry2000
10595536Mutations of endo-beta-N-acetylglucosaminidase H active site residueAs sp130 anG glu132: activities and conformations.Protein Sci1999
10047486Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI.J Mol Biol1999
10091656Crystal structure of thymidylate synthase A from Bacillus subtilis.Protein Sci1999
9541410Crystal structure of glycosylasparaginase from Flavobacterium meningosepticum.Protein Sci1998
10089530Crystallization and preliminary crystallographic analysis of the archaeal intron-encoded endonuclease I-DmoI.Acta Crystallogr D Biol Crystallogr1998
7493989Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F.J Biol Chem1995
7663942Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition.Structure1995
7918386Crystal structure of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F at 2.2-A resolution.Biochemistry1994
8133514Crystallization and preliminary crystallographic analysis of two endo-beta-N-acetylglucosaminidases, endo H and endo F1.J Mol Biol1994
8057383Crystallization and preliminary crystallographic analysis of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase PNGase F.J Mol Biol1994
7947807Crystal structure of endo-beta-N-acetylglucosaminidase F1, an alpha/beta-barrel enzyme adapted for a complex substrate.Biochemistry1994
1597854Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.J Med Chem1992
1669441Structure-activity studies of non-steroidal aromatase inhibitors: the crystal and molecular structures of CGS 16949A and CGS 18320B.J Enzyme Inhib1991
1863426Structure of (+/-)-aminoglutethimide.Acta Crystallogr C1991
1930813Structure of cis-1-([4-(1-imidazolylmethyl)cyclohexyl]methyl)imidazole- succinic acid complex.Acta Crystallogr C1991
1706572Correlation of molecular conformation and activity of reverse transcriptase inhibitors.Ann N Y Acad Sci1990
2726758Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.Proc Natl Acad Sci U S A1989
2771945Crystal structure analysis of auromomycin apoprotein (macromomycin) shows importance of protein side chains to chromophore binding selectivity.Proc Natl Acad Sci U S A1989
3271082Structure of 4-methylumbelliferyl-beta-D-glucopyranoside.Acta Crystallogr C1988
3172772Crystallization of prostatic binding protein.J Steroid Biochem1988
6654587Crystal and molecular structure of tert.-butyloxycarbonyl-L-prolyl-alpha-aminoisobutyryl-L-alanyl-alpha- aminoisobutyrate methyl ester.Int J Pept Protein Res1983
7118420Crystal and molecular structure of tert.-butyloxycarbonyl-L-hydroxy-prolyl-alpha-aminoisobutyryl-alpha-aminoisobutyryl-L-phenylalaninol.Int J Pept Protein Res1982
7338912Preliminary crystallographic study of macromomycin.J Mol Biol1981
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Collaborators

University of Tubingen
Co-authored papers 3
University of California San Francisco
Co-authored papers 1
Howard Hughes Medical Institute, Inc. at the Wadsworth Center
Co-authored papers 1
University of Missouri
Co-authored papers 1
RNA Therapeutics Institute, University of Massachusetts Chan Medical School
Co-authored papers 1
Florida State University
Co-authored papers 1
University of California at San Francisco
Co-authored papers 1
School of Public Health, University at Albany
Co-authored papers 1
Columbia University
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1
Institute of Child Health
Co-authored papers 1
Center for Cooperative Research in Biosciences (CIC bioGUNE)
Co-authored papers 1
Columbia University Medical Center
Co-authored papers 1