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Author Details

Derek S Welsbie
Shiley Eye Institute, University of California
1999
38
20
PMIDPaper TitleJournal TitlePublished Year
36038107A Deep Learning Approach to Improve Retinal Structural Predictions and Aid Glaucoma Neuroprotective Clinical Trial Design.Ophthalmol Glaucoma2023
37624696Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy.Cell Rep2023
37773257Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming.NPJ Regen Med2023
36877820Usability and Clinician Acceptance of a Deep Learning-Based Clinical Decision Support Tool for Predicting Glaucomatous Visual Field Progression.J Glaucoma2023
36680758Traumatic Axonal Injury in the Optic Nerve: The Selective Role of SARM1 in the Evolution of Distal Axonopathy.J Neurotrauma2023
35313474Polymorphous low-grade adenocarcinoma with cavernous sinus involvement presenting as third nerve palsy.Am J Ophthalmol Case Rep2022
35981522Live, die, or regenerate? New insights from multi-omic analyses.Neuron2022
35189184Superior segmental optic nerve hypoplasia: A review.Surv Ophthalmol2022
34283208Optic Nerve Engraftment of Neural Stem Cells.Invest Ophthalmol Vis Sci2021
33626360Qualitative Evaluation of the 10-2 and 24-2 Visual Field Tests for Detecting Central Visual Field Abnormalities in Glaucoma.Am J Ophthalmol2021
33529795Progressive Thinning of Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer in Glaucoma Eyes with Disc Hemorrhage.Ophthalmol Glaucoma2021
32645310A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy.Am J Ophthalmol2020
32023037Genetically Encodable Contrast Agents for Optical Coherence Tomography.ACS Nano2020
33318207Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons.Proc Natl Acad Sci U S A2020
32883010Potential of Ocular Transmission of SARS-CoV-2: A Review.Vision (Basel)2020
32955495Sheath-Preserving Optic Nerve Transection in Rats to Assess Axon Regeneration and Interventions Targeting the Retinal Ganglion Cell Axon.J Vis Exp2020
30999387Aqueous shunts with mitomycin C versus aqueous shunts alone for glaucoma.Cochrane Database Syst Rev2019
31775817Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury.Mol Neurodegener2019
29526794Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.Exp Eye Res2018
30309916Thyroid hormone signaling specifies cone subtypes in human retinal organoids.Science2018
28641113Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.Neuron2017
29024560Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells.Stem Cells Transl Med2017
27481653Characterization of intravitreally delivered capsid mutant AAV2-Cre vector to induce tissue-specific mutations in murine retinal ganglion cells.Exp Eye Res2016
25683606Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion.J Neurochem2015
26621751Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A.Proc Natl Acad Sci U S A2015
26505191Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma.PLoS One2015
23431148Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.Proc Natl Acad Sci U S A2013
24175744Dual leucine zipper kinase as a therapeutic target for neurodegenerative conditions.Future Med Chem2013
24232085More than just optic disc swelling.JAMA Ophthalmol2013
23959876Hypoxic retinal Muller cells promote vascular permeability by HIF-1-dependent up-regulation of angiopoietin-like 4.Proc Natl Acad Sci U S A2013
22051675Melanopsin signalling in mammalian iris and retina.Nature2011
19176386Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer.Cancer Res2009
19359544Development of a second-generation antiandrogen for treatment of advanced prostate cancer.Science2009
16341243Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.Nat Med2006
16492776Ligand-specific allosteric regulation of coactivator functions of androgen receptor in prostate cancer cells.Proc Natl Acad Sci U S A2006
14702632Molecular determinants of resistance to antiandrogen therapy.Nat Med2004
15564576Lateral hypothalamic signaling mechanisms underlying feeding stimulation: differential contributions of Src family tyrosine kinases to feeding triggered either by NMDA injection or by food deprivation.J Neurosci2004
10455151Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein.J Biol Chem1999
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Collaborators

Robert N Weinreb
Shiley Eye Institute, University of California San Diego
Co-authored papers 10
Donald J Zack
Johns Hopkins University School of Medicine
Co-authored papers 9
Jiun L Do
Shiley Eye Institute, University of California
Co-authored papers 6
Charles L Sawyers
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Andrew S Camp
Shiley Eye Institute, University of California San Diego
Co-authored papers 4
James A Proudfoot
Shiley Eye Institute, University of California
Co-authored papers 3
Linda M Zangwill
Shiley Eye Institute, University of California San Diego
Co-authored papers 3
Christopher A Girkin
Heersink School of Medicine, University of Alabama-Birmingham
Co-authored papers 3
Sasan Moghimi
Shiley Eye Institute, University of California San Diego
Co-authored papers 3
Tian Xue
Co-authored papers 2
Howard I Scher
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Jeffrey M Liebmann
Edward S. Harkness Eye Institute, Columbia University Medical Center
Co-authored papers 2
Massimo A Fazio
Heersink School of Medicine, University of Alabama-Birmingham
Co-authored papers 2
Mark Christopher
Shiley Eye Institute, university of california san diego
Co-authored papers 2
Michael G Rosenfeld
University of California San Diego
Co-authored papers 2
Daniel L Chao
Shiley Eye Institute, University of San Diego
Co-authored papers 2
Yu Chen
School of Pharmacy, University of Wisconsin-Madison
Co-authored papers 2
Thomas J George
UF Health Cancer Center
Co-authored papers 1
Robert L Vessella
University of Washington
Co-authored papers 1
Sally L Baxter
University of California San Diego
Co-authored papers 1
Kym F Faull
Co-authored papers 1
Andrew T Kwon
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 1
Ze'ev Ronai
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Huiyuan Hou
Shiley Eye Institute, University of California
Co-authored papers 1
Charles G Eberhart
Wilmer Eye Institute, Johns Hopkins Medical Institutions
Co-authored papers 1
Alexander Lieu
Viterbi Family Department of Ophthalmology and Shiley Eye Institute.
Co-authored papers 1
Iain D C Fraser
Co-authored papers 1
Celestia S Higano
University of Washington and Fred Hutchinson Cancer Research Center
Co-authored papers 1
Arnold R Kriegstein
University of California san francisco
Co-authored papers 1
Johannes Czernin
university of california los angeles
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Release 1.2