Author details

Full Name

Helder I Nakaya

Affiliation

ORCID

Career Start Year

2004

Papers

160

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36597912	Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID-19 severity.		2023
37561669	Ten quick tips for harnessing the power of ChatGPT in computational biology.		2023
36582189	Combining IP affinity chromatography and bioinformatics reveals a novel protein-IP binding site on MDR1 transporter.		2023
37457727	Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress.		2023
36921684	S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.		2023
37104043	C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.		2023
36985226	Gene Signatures of Symptomatic and Asymptomatic Clinical-Immunological Profiles of Human Infection by () in Amazonian Brazil.		2023
35005554	The evolution of knowledge on genes associated with human diseases.	iScience	2022
35651746	Automatic detection of the parasite in blood smears using a machine learning approach applied to mobile phone images.	PeerJ	2022
35951647	Morphological, cellular, and molecular basis of brain infection in COVID-19 patients.	Proceedings of the National Academy of Sciences of the United States of America	2022
35739193	Molecular alterations in human milk in simulated maternal nasal mucosal infection with live attenuated influenza vaccination.	Mucosal Immunology	2022
35370994	Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Infection.	Frontiers in Immunology	2022
35677061	Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors.	Frontiers in Immunology	2022
35666101	Efferocytosis of SARS-CoV-2-infected dying cells impairs macrophage anti-inflammatory functions and clearance of apoptotic cells.	eLife	2022
36405692	SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies.	Frontiers in Immunology	2022
36396745	Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections.	Scientific Reports	2022
36578476	Chikungunya patient transcriptional signatures faithfully recapitulated in a C57BL/6J mouse model.		2022
36577385	Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.		2022
36685903	Comparative transcriptomic analysis of long noncoding RNAs in -infected human macrophages.		2022
36685521	Immunodominant antibody responses directed to SARS-CoV-2 hotspot mutation sites and risk of immune escape.		2022
36661509	Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection.	Curr Issues Mol Biol	2022
35335996	Acute Inflammation Is a Predisposing Factor for Weight Gain and Insulin Resistance.	Pharmaceutics	2022
35269470	Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory States.	Cells	2022
34978070	Aryl hydrocarbon receptor (AhR) activation contributes to high-fat diet-induced vascular dysfunction.	British Journal of Pharmacology	2022
34528687	Long non-coding RNAs associated with infection and vaccine-induced immunity.	Essays in Biochemistry	2021
34238385	OUTBREAK: a user-friendly georeferencing online tool for disease surveillance.	Biological Research	2021
33751207	Linking proteomic alterations in schizophrenia hippocampus to NMDAr hypofunction in human neurons and oligodendrocytes.	Eur Arch Psychiatry Clin Neurosci	2021
33907239	Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load.	Scientific Reports	2021
33587339	Profiling plasma-extracellular vesicle proteins and microRNAs in diabetes onset in middle-aged male participants in the ELSA-Brasil study.	Physiological Reports	2021
33777004	Systems Biology Analysis of the Radiation-Attenuated Schistosome Vaccine Reveals a Role for Growth Factors in Protection and Hemostasis Inhibition in Parasite Survival.	Frontiers in Immunology	2021
34141989	An Experimental DUAL Model of Advanced Liver Damage.	Hepatology Communications	2021
34027897	The relationship between cytokine and neutrophil gene network distinguishes SARS-CoV-2-infected patients by sex and age.	JCI Insight	2021
34026666	P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis.	Frontiers in Cellular and Infection Microbiology	2021
33498214	Human Transcriptomic Response to the VSV-Vectored Ebola Vaccine.	Vaccines	2021
34330510	Gene signatures of autopsy lungs from obese patients with COVID-19.	Clinical Nutrition ESPEN	2021
34312428	Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock.	Scientific Reports	2021
33863789	Kdm6b Regulates the Generation of Effector CD8 T Cells by Inducing Chromatin Accessibility in Effector-Associated Genes.	Journal of Immunology	2021
33497364	Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine.	JCI insight	2021
33129683	Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol.		2021
34867992	Co-Exposure of Cardiomyocytes to IFN-Î³ and TNF-Î± Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy.	Frontiers in Immunology	2021
34407544	Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation.	Blood	2021
34854707	Whole-Genome Sequencing of Leishmania infantum chagasi Isolates from Honduras and Brazil.	Microbiology Resource Announcements	2021
34556875	Hidden in plain sight: uncovering the role of CREB1 in HIV-1 vaccine-induced immunity.	Nature Immunology	2021
34490283	Acid pH Increases SARS-CoV-2 Infection and the Risk of Death by COVID-19.	Front Med (Lausanne)	2021
34824230	Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.	Nature Communications	2021
34473957	Sepsis expands a CD39 plasmablast population that promotes immunosuppression via adenosine-mediated inhibition of macrophage antimicrobial activity.	Immunity	2021
34585667	Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in patients.	eLife	2021
33162295	Network vaccinology.	Seminars in Immunology	2020
32428113	Susceptibility of the Elderly to SARS-CoV-2 Infection: ACE-2 Overexpression, Shedding, and Antibody-dependent Enhancement (ADE).	Clinics	2020
32362926	SÃ£o Paulo School of Advanced Sciences on Vaccines: an overview.	Journal of Venomous Animals and Toxins Including Tropical Diseases	2020