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Author Details

Magda Babina
Berlin Institute of Health
1996
84
27
PMIDPaper TitleJournal TitlePublished Year
36089079MRGPRX2 in drug allergy: What we know and what we do not know.J Allergy Clin Immunol2023
38067128Synergism between IL-33 and MRGPRX2/FcεRI Is Primarily Due to the Complementation of Signaling Modules, and Only Modestly Supplemented by Prolonged Activation of Selected Kinases.Cells2023
37174705Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells.Cells2023
36835547CREB Is Activated by the SCF/KIT Axis in a Partially ERK-Dependent Manner and Orchestrates Survival and the Induction of Immediate Early Genes in Human Skin Mast Cells.Int J Mol Sci2023
34329659Cytokine Stimulation by MRGPRX2 Occurs with Lower Potency than by FcεRI Aggregation but with Similar Dependence on the Extracellular Signal-Regulated Kinase 1/2 Module in Human Skin Mast Cells.J Invest Dermatol2022
35652819The SCF/KIT axis in human mast cells: Capicua acts as potent KIT repressor and ERK predominates PI3K.Allergy2022
35346330Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study.Trials2022
35662539Diversities of allergic pathologies and their modifiers: Report from the second DGAKI-JSA meeting.Allergol Int2022
35910860β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells.Front Allergy2022
36142795How "Neuronal" Are Human Skin Mast Cells?Int J Mol Sci2022
36225266An interdisciplinary approach to characterize peanut-allergic patients-First data from the FOOD@ consortium.Clin Transl Allergy2022
35279213Tolerance induction through early feeding to prevent food allergy in infants with eczema (TEFFA): rationale, study design, and methods of a randomized controlled trial.Trials2022
35246987FcεRI- and MRGPRX2-evoked acute degranulation responses are fully additive in human skin mast cells.Allergy2022
35240143Mast cells instruct keratinocytes to produce thymic stromal lymphopoietin: Relevance of the tryptase/protease-activated receptor 2 axis.J Allergy Clin Immunol2022
35326404MRGPRX2-Mediated Degranulation of Human Skin Mast Cells Requires the Operation of G<sub>αi</sub>, G<sub>αq</sub>, Ca++ Channels, ERK1/2 and PI3K-Interconnection between Early and Late Signaling.Cells2022
35202004Serological profiling reveals hsa-miR-451a as a possible biomarker of anaphylaxis.JCI Insight2022
33071069Mas-related G protein-coupled receptor X2 and its activators in dermatologic allergies.J Allergy Clin Immunol2021
33808264Cytokines Stimulated by IL-33 in Human Skin Mast Cells: Involvement of NF-κB and p38 at Distinct Levels and Potent Co-Operation with FcεRI and MRGPRX2.Int J Mol Sci2021
33058860MRGPRX2 Is the Codeine Receptor of Human Skin Mast Cells: Desensitization through β-Arrestin and Lack of Correlation with the FcεRI Pathway.J Invest Dermatol2021
33429916Thymic Stromal Lymphopoietin Promotes MRGPRX2-Triggered Degranulation of Skin Mast Cells in a STAT5-Dependent Manner with Further Support from JNK.Cells2021
30924922Thymic stromal lymphopoietin production induced by skin irritation results from concomitant activation of protease-activated receptor 2 and interleukin 1 pathways.Br J Dermatol2020
31978350An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.Cell2020
32766969Integration of the Human Dermal Mast Cell into the Organotypic Co-culture Skin Model.Methods Mol Biol2020
32866307MRGPRX2 signals its importance in cutaneous mast cell biology: Does MRGPRX2 connect mast cells and atopic dermatitis?Exp Dermatol2020
32407837PGE<sub>2</sub> deficiency predisposes to anaphylaxis by causing mast cell hyperresponsiveness.J Allergy Clin Immunol2020
30684550Yin-Yang of IL-33 in Human Skin Mast Cells: Reduced Degranulation, but Augmented Histamine Synthesis through p38 Activation.J Invest Dermatol2019
31387206Thymic Stromal Lymphopoietin Interferes with the Apoptosis of Human Skin Mast Cells by a Dual Strategy Involving STAT5/Mcl-1 and JNK/Bcl-x<sub>L</sub>.Cells2019
31585081An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.Cell2019
31393642Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway.Mol Nutr Food Res2019
30979016IL-33 and MRGPRX2-Triggered Activation of Human Skin Mast Cells-Elimination of Receptor Expression on Chronic Exposure, but Reinforced Degranulation on Acute Priming.Cells2019
28859248Allergic FcεRI- and pseudo-allergic MRGPRX2-triggered mast cell activation routes are independent and inversely regulated by SCF.Allergy2018
30091263MRGPRX2 is negatively targeted by SCF and IL-4 to diminish pseudo-allergic stimulation of skin mast cells in culture.Exp Dermatol2018
27677092Skin mast cell phenotypes between two highly divergent cohorts - more pronounced variability within than between groups.Exp Dermatol2017
28219062The Impact on Allergy-Related Cells of a Birch Pollen Allergoid, with and without Monophosphoryl Lipid A, in Comparison with the Native Equivalent.Int Arch Allergy Immunol2017
28378321Serum levels of 9α,11β-PGF<sub>2</sub> and apolipoprotein A1 achieve high predictive power as biomarkers of anaphylaxis.Allergy2017
28241135An atlas of human long non-coding RNAs with accurate 5' ends.Nature2017
28264498Retinoic Acid Negatively Impacts Proliferation and MC<sub>TC</sub> Specific Attributes of Human Skin Derived Mast Cells, but Reinforces Allergic Stimulability.Int J Mol Sci2017
28418623An efficient method for gene knock-down by RNA interference in human skin mast cells.Exp Dermatol2017
28829439An integrated expression atlas of miRNAs and their promoters in human and mouse.Nat Biotechnol2017
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
28845295Apoptotic resistance of human skin mast cells is mediated by Mcl-1.Cell Death Discov2017
27111856Bortezomib treatment diminishes hazelnut-induced intestinal anaphylaxis in mice.Eur J Immunol2016
26292777Serum levels of 9α,11β-PGF2 and cysteinyl leukotrienes are useful biomarkers of anaphylaxis.J Allergy Clin Immunol2016
27650274IL-4 and human skin mast cells revisited: reinforcement of a pro-allergic phenotype upon prolonged exposure.Arch Dermatol Res2016
26706922Phenotypic variability in human skin mast cells.Exp Dermatol2016
25307606Thymic stromal lymphopoietin induction by skin irritation is independent of tumour necrosis factor-α, but supported by interleukin-1.Br J Dermatol2015
26392054Impact of sex on anaphylaxis severity--data from the Anaphylaxis Registry.J Allergy Clin Immunol2015
25717144Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells.J Leukoc Biol2015
25725371Retinoic acid potentiates inflammatory cytokines in human mast cells: identification of mast cells as prominent constituents of the skin retinoid network.Mol Cell Endocrinol2015
25441633Ramipril and metoprolol intake aggravate human and murine anaphylaxis: evidence for direct mast cell priming.J Allergy Clin Immunol2015
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Collaborators

Berlin Institute of Health
Co-authored papers 30
RIKEN Center for Integrative Medical Sciences
Co-authored papers 7
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Center for Integrative Medical Sciences
Co-authored papers 6
Telethon Kids Institute, University of Western Australia
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Center for Integrative Medical Sciences
Co-authored papers 5
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 4
University Hospital Regensburg
Co-authored papers 4
Center for Integrative Medical Sciences
Co-authored papers 4
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 4
The University of Melbourne
Co-authored papers 4
Yong Loo Lin School of Medicine, National University of Singapore
Co-authored papers 4
RIKEN Center for Life Science Technologies
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Cerevance Ltd
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
German Center for Neurodegenerative Diseases (DZNE).
Co-authored papers 4
Kyungpook National University, Kyungpook National University Hospital
Co-authored papers 3
Ohu University School of Pharmaceutical Sciences
Co-authored papers 3
Institute of Industrial Science, The University of Tokyo
Co-authored papers 3
Harry Perkins Institute of Medical Research
Co-authored papers 3
Genome Institute of Singapore (GIS)
Co-authored papers 3
Karolinska Institute
Co-authored papers 3
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 3
University of British Columbia
Co-authored papers 3
Child and Family Research Institute, University of British Columbia
Co-authored papers 3