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Author Details

Gregory M Laird
2010
39
24
PMIDPaper TitleJournal TitlePublished Year
37379584HIV-Positive Liver Transplant Does not Alter the Latent Viral Reservoir in Recipients With Antiretroviral Therapy-Suppressed HIV.J Infect Dis2023
37463049The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy.J Clin Invest2023
36763044Varied Patterns of Decay of Intact Human Immunodeficiency Virus Type 1 Proviruses Over 2 Decades of Antiretroviral Therapy.J Infect Dis2023
37126090Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary.AIDS Res Hum Retroviruses2023
36448802The BCL-2 Inhibitor Venetoclax Augments Immune Effector Function Mediated by Fas Ligand, TRAIL, and Perforin/Granzyme B, Resulting in Reduced Plasma Viremia and Decreased HIV Reservoir Size during Acute HIV Infection in a Humanized Mouse Model.Journal of Virology2022
36345940The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir.JCI Insight2022
34901797Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo.eClinicalMedicine2021
34162752The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy.Sci Transl Med2021
33043969Vesatolimod, a Toll-like Receptor 7 Agonist, Induces Immune Activation in Virally Suppressed Adults Living With Human Immunodeficiency Virus-1.Clinical Infectious Diseases2021
32823274Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy.J Infect Dis2021
33037877Nonstructured Treatment Interruptions Are Associated With Higher Human Immunodeficiency Virus Reservoir Size Measured by Intact Proviral DNA Assay in People Who Inject Drugs.J Infect Dis2021
33269401Similar Frequency and Inducibility of Intact Human Immunodeficiency Virus-1 Proviruses in Blood and Lymph Nodes.J Infect Dis2021
33115867Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103[+] and Gut CD4[+] T Cells.J Virol2020
31895150Elite suppressors have low frequencies of intact HIV-1 proviral DNA.AIDS2020
32045386Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy.JCI Insight2020
32690683Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA.Proc Natl Acad Sci U S A2020
32848246Distinct viral reservoirs in individuals with spontaneous control of HIV-1.Nature2020
31295427The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.Cell Host Microbe2019
30700913A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.Nature2019
29433524Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir.Retrovirology2018
30232425The role of CD32 during HIV-1 infection.Nature2018
27898590Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques.AIDS2017
28656019Characterization of Elite Suppressors Cell-Associated HIV-1 mRNA at Baseline and with T Cell Activationâ¿©â¿©.Yale J Biol Med2017
29045905Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4<sup>+</sup> T Cells Permissive for Latent HIV-1 Infection.Immunity2017
26714716Measuring the Frequency of Latent HIV-1 in Resting CD4⁺ T Cells Using a Limiting Dilution Coculture Assay.Methods Mol Biol2016
26035316Medroxyprogesterone acetate increases HIV-1 infection of unstimulated peripheral blood mononuclear cells in vitro.AIDS2015
25822022Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.J Clin Invest2015
24658076New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.Nat Med2014
24275119A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides.J Antimicrob Chemother2014
24713404Role of autophagy genetic variants for the risk of Candida infections.Med Mycol2014
24799684Measuring reversal of HIV-1 latency ex vivo using cells from infected individuals.Proc Natl Acad Sci U S A2014
23737751Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay.PLoS Pathog2013
23979165Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance.J Clin Invest2013
24177428CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.J Clin Invest2013
23536672A novel PCR assay for quantification of HIV-1 RNA.J Virol2013
22144535Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.Clin Infect Dis2012
22301633Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.J Infect Dis2012
21881131Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia.J Infect Dis2011
20671299Lipidomics reveals a remarkable diversity of lipids in human plasma.J Lipid Res2010
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