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Author Details

Anastasia Nijnik
McGill University
2003
51
24
PMIDPaper TitleJournal TitlePublished Year
36738766Histone H2A deubiquitinases in the transcriptional programs of development and hematopoiesis: a consolidated analysis.Int J Biochem Cell Biol2023
37688495Dysregulation of B lymphocyte development in the SKG mouse model of rheumatoid arthritis.Immunology2023
36611064Deubiquitinase catalytic activity of MYSM1 is essential in vivo for hematopoiesis and immune cell development.Sci Rep2023
34913882Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia.Pain2022
36561751Hematologic dysfunction in cancer: Mechanisms, effects on antitumor immunity, and roles in disease progression.Front Immunol2022
33462414Roles and mechanisms of BAP1 deubiquitinase in tumor suppression.Cell Death Differ2021
33912157Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1.Front Immunol2021
34858388Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1⿿3)-β-D-Glucan.Front Immunol2021
34625535p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress.Cell Death Dis2021
34531456A forward genetic screen identifies modifiers of rocaglate responsiveness.Sci Rep2021
34114734Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma.J Cell Mol Med2021
32344625Deubiquitinase MYSM1 in the Hematopoietic System and beyond: A Current Review.Int J Mol Sci2020
33125891M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity.Cell2020
32641579MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction.JCI Insight2020
30639577USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model.Exp Hematol2019
31636138A Loss-of-Function Mutation in the Integrin Alpha L (<i>Itgal</i>) Gene Contributes to Susceptibility to Salmonella enterica Serovar Typhimurium Infection in Collaborative Cross Strain CC042.Infect Immun2019
29328912BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.Cell2018
27833034Mysm1 expression in the bone marrow niche is not essential for hematopoietic maintenance.Exp Hematol2017
27895164MYSM1-dependent checkpoints in B cell lineage differentiation and B cell-mediated immune response.J Leukoc Biol2017
28066899A role for the histone H2A deubiquitinase MYSM1 in maintenance of CD8<sup>+</sup> T cells.Immunology2017
26768662Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.Cell Death Differ2016
27500495BRPF1 is essential for development of fetal hematopoietic stem cells.J Clin Invest2016
25680095Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation.PLoS One2015
26125289Deubiquitinase MYSM1 Is Essential for Normal Fetal Liver Hematopoiesis and for the Maintenance of Hematopoietic Stem Cells in Adult Bone Marrow.Stem Cells Dev2015
25710881p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.Blood2015
24647359H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology.Int J Biochem Cell Biol2014
25356849Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss.PLoS Genet2014
23109507Manipulation of innate immunity by a bacterial secreted peptide: lantibiotic nisin Z is selectively immunomodulatory.Innate Immun2013
23870826Immunomodulatory approaches for prevention and treatment of infectious diseases.Curr Opin Microbiol2013
22184403The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.Blood2012
22516952Signaling pathways mediating chemokine induction in keratinocytes by cathelicidin LL-37 and flagellin.J Innate Immun2012
22664872The role of sphingosine-1-phosphate transporter Spns2 in immune system function.J Immunol2012
22246800The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.J Leukoc Biol2012
22421877Modulating immunity as a therapy for bacterial infections.Nat Rev Microbiol2012
20123131Hematopoietic cell types: prototype for a revised cell ontology.J Biomed Inform2011
20811938Cathelicidin peptide LL-37 modulates TREM-1 expression and inflammatory responses to microbial compounds.Inflammation2011
20107187Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment.J Immunol2010
19068548The roles of cathelicidin LL-37 in immune defences and novel clinical applications.Curr Opin Hematol2009
22460279Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections.Emerg Health Threats J2009
19683819Potential of immunomodulatory host defense peptides as novel anti-infectives.Trends Biotechnol2009
19605696Intracellular receptor for human host defense peptide LL-37 in monocytes.J Immunol2009
19812202Human cathelicidin peptide LL-37 modulates the effects of IFN-gamma on APCs.J Immunol2009
19451691Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.J Clin Invest2009
19539585A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.Vaccine2009
17312136Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice.J Immunol2007
17554302DNA repair is limiting for haematopoietic stem cells during ageing.Nature2007
16341054An investigation of transmission ratio distortion in the central region of the human MHC.Genes Immun2006
16738941Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.Immunogenetics2006
16735376Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.Int Immunol2006
16477212B-cell tolerance.Transplantation2006
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Collaborators

Robert E W Hancock
University of British Columbia
Co-authored papers 13
David Langlais
McGill University
Co-authored papers 11
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 3
Brendan J Keating
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Neil A Hanchard
Baylor College of Medicine.
Co-authored papers 2
Timothy A Lewis
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Richard H Scheuermann
J. Craig Venter Institute
Co-authored papers 1
Q Alison Yao
Co-authored papers 1
Terrence F Meehan
European Bioinformatics Institute
Co-authored papers 1
Nicole F Bernard
Co-authored papers 1
Lindsay G Cowell
University of Texas Southwestern Medical Center
Co-authored papers 1
Elizabeth S Gold
Seattle Children's Research Institute
Co-authored papers 1
Alexander D Diehl
Jacobs School of Medicine and Biomedical Sciences, University at Buffalo
Co-authored papers 1
Alison Deckhut Augustine
National Institute of Allergy and Infectious Diseases/National Institutes of Health
Co-authored papers 1
Penelope A Morel
University of Pittsburgh
Co-authored papers 1
Bendik S Winsvold
Co-authored papers 1
Bjoern Peters
University of Washington School of Medicine
Co-authored papers 1
Martin S Zand
University of Rochester Medical Center
Co-authored papers 1
Anna Maria Masci
Duke University School of Medicine
Co-authored papers 1
Bali Pulendran
Institute for Immunity, Stanford University School of Medicine, Stanford University
Co-authored papers 1
Lars G Fritsche
Co-authored papers 1
Judith A Blake
Co-authored papers 1
Christopher J Mungall
International Society for Biocuration, Lawrence Berkeley National Laboratory, University of Edinburgh, University of Edinburgh School of Biological Sciences
Co-authored papers 1
David J Adams
Wellcome Sanger Institute
Co-authored papers 1
Kosuke Yusa
Wellcome Sanger Institute
Co-authored papers 1
Richard Mott
Co-authored papers 1
Release 1.2