Author details

Full Name

Yii-Der Ida Chen

Affiliation

ORCID

Career Start Year

1977

Papers

548

H Index

102

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37546893	Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus.	medRxiv	2023
36444934	Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease.	Hum Mol Genet	2023
36379261	Infertility and treatments used have minimal effects on first-trimester placental DNA methylation and gene expression.	Fertil Steril	2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37662265	WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.	medRxiv	2023
37587153	Genome-wide association studies and fine-mapping identify genomic loci for n-3 and n-6 polyunsaturated fatty acids in Hispanic American and African American cohorts.	Commun Biol	2023
37582364	Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma.	Cell Metab	2023
37992186	Increased plasma branched short-chain fatty acids and improved glucose homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).		2023
37802043	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.	Am J Hum Genet	2023
37709864	Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease.	Nat Genet	2023
37609230	A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization.	medRxiv	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
36778386	Structural variation across 138,134 samples in the TOPMed consortium.	Res Sq	2023
37268629	Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups.	Nat Commun	2023
37397985	Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.	bioRxiv	2023
36702996	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.	Nat Genet	2023
37126548	The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.	Sci Adv	2023
37005925	Metabolomic profiling of glucose homeostasis in African Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS-FS).	Metabolomics	2023
36747810	Structural variation across 138,134 samples in the TOPMed consortium.	bioRxiv	2023
36865120	Genome-Wide Association Studies and fine-mapping of genomic loci for n-3 and n-6 Polyunsaturated Fatty Acids in Hispanic American and African American Cohorts.	Res Sq	2023
37046083	Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.	Nature	2023
36735419	OMEGA-3 FATTY ACIDS ARE ASSOCIATED WITH DECREASED PRESENCE AND SEVERITY OF DIABETIC RETINOPATHY: A Combined Analysis of MESA and GOLDR Cohorts.	Retina	2023
36791419	Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.	Diabetes	2023
37425772	Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.	medRxiv	2023
37292936	Genome-wide association identifies novel ROP risk loci in a multi-ethnic cohort.	Res Sq	2023
35085396	Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.	Diabetes Care	2022
35972231	Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).		2022
35654975	A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.	Nat Genet	2022
35459606	Associations between adherence to the dietary approaches to stop hypertension (DASH) diet and six glucose homeostasis traits in the Microbiome and Insulin Longitudinal Evaluation Study (MILES).	Nutr Metab Cardiovasc Dis	2022
35459606	Associations between adherence to the dietary approaches to stop hypertension (DASH) diet and six glucose homeostasis traits in the Microbiome and Insulin Longitudinal Evaluation Study (MILES).	Nutr Metab Cardiovasc Dis	2022
35652341	Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.	Hypertension	2022
35385311	Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential.	Sci Adv	2022
36220816	Whole genome sequence analysis of blood lipid levels in >66,000 individuals.	Nat Commun	2022
36220816	Whole genome sequence analysis of blood lipid levels in >66,000 individuals.	Nat Commun	2022
36144194	The Roles of Gut Microbiome and Plasma Metabolites in the Associations between ABO Blood Groups and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).	Metabolites	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
36268164	Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.	HGG Adv	2022
35673403	Cesarean Delivery and Insulin Sensitivity in the Older Adult: The Microbiome and Insulin Longitudinal Evaluation Study.	Journal of the Endocrine Society	2022
35399580	Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.	HGG Adv	2022
36477530	Genetic diversity fuels gene discovery for tobacco and alcohol use.	Nature	2022
34743536	Clonal Hematopoiesis Is Associated With Higher Risk of Stroke.	Stroke	2022
34913723	AtheroSpectrum Reveals Novel Macrophage Foam Cell Gene Signatures Associated With Atherosclerotic Cardiovascular Disease Risk.	Circulation	2022
34855941	Association of clonal hematopoiesis with chronic obstructive pulmonary disease.	Blood	2022
35265679	Rare Genetic Variants Associated With Myocardial Fibrosis: Multi-Ethnic Study of Atherosclerosis.	Front Cardiovasc Med	2022
34727735	Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project.	Stroke	2022
34553764	Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative.	Hum Mol Genet	2022
35142845	Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis of 12 Prospective Cohort Studies in the Fatty Acids and Outcomes Research Consortium (FORCE).	Diabetes Care	2022
34951656	Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.	Diabetologia	2022
34814699	Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.	Circulation	2022
34814699	Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.	Circulation	2022