Author details

Full Name

Jin-Ichi Inokuchi

Affiliation

ORCID

Career Start Year

1978

Papers

142

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36690566	Neurological insights on two siblings with GM3 synthase deficiency due to novel compound heterozygous ST3GAL5 variants.		2023
36255673	Synthesis of O-Linked Glycoconjugates in the Nervous System.	Advances in neurobiology	2023
37565654	Chronic encephalomyelitis virus exhibits cellular tropism and evades pDCs by binding to sialylated integrins as the cell surface receptors.		2023
36587076	Mass Spectrometry of Neutral Glycosphingolipids.		2023
36587074	Sialyltransferase Activity Assay for Ganglioside GM3 Synthase.		2023
37249637	Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells.	Cell Mol Life Sci	2023
35156158	Gangliosides in T cell development and function of mice.	Glycoconjugate Journal	2022
35712350	Pathophysiological Significance of GM3 Ganglioside Molecular Species With a Particular Attention to the Metabolic Syndrome Focusing on Toll-Like Receptor 4 Binding.	Frontiers in Molecular Biosciences	2022
35628171	Ganglioside GM3 Synthase Deficiency in Mouse Models and Human Patients.	International Journal of Molecular Sciences	2022
36335793	GM3 synthase deficiency increases brain glucose metabolism in mice.	Molecular Genetics and Metabolism	2022
36065662	Fond Memories of Professor Sen-itiroh Hakomori.	Journal of Biochemistry	2022
35775650	Functional validation of novel variants in B4GALNT1 associated with early-onset complex hereditary spastic paraplegia with impaired ganglioside synthesis.	Am J Med Genet A	2022
34125497	Homeostatic and pathogenic roles of the GM3 ganglioside.		2022
34516001	GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis.	EMBO Journal	2021
32731387	Roles of Gangliosides in Hypothalamic Control of Energy Balance: New Insights.	International Journal of Molecular Sciences	2020
32378734	Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.	EMBO J	2020
31874824	The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation.	Bioorganic and Medicinal Chemistry Letters	2020
30888588	Overexpression of HexCer and LacCer containing 2-hydroxylated fatty acids in cholangiocarcinoma and the association of the increase of LacCer (d18:1-h23:0) with shorter survival of the patients.	Glycoconjugate Journal	2019
31674925	Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.	Journal of Clinical Investigation	2019
30476082	Globo-series glycosphingolipids enhance Toll-like receptor 4-mediated inflammation and play a pathophysiological role in diabetic nephropathy.	Glycobiology	2019
30561621	Plasma membrane sphingomyelin modulates thymocyte development by inhibiting TCR-induced apoptosis.	International Immunology	2019
30688114	Visual Function in Mice Lacking GM3 Synthase.	Current Eye Research	2019
31264973	Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.	Journal of Clinical Investigation	2019
31004109	Serum GM3(d18:1-16:0) and GM3(d18:1-24:1) levels may be associated with lymphoma: An exploratory study with haematological diseases.	Scientific Reports	2019
29288569	Sex-based differences in CD103 dendritic cells promote female-predominant Th2 cytokine production during allergic asthma.	Clinical and Experimental Allergy	2018
29926420	Pharmacological Modulation of Glycosphingolipid Metabolism.	Methods in Molecular Biology	2018
29926410	Mass Spectrometry of Gangliosides.	Methods in Molecular Biology	2018
29880531	Deficient ganglioside synthesis restores responsiveness to leptin and melanocortin signaling in obese KKAy mice.	Journal of Lipid Research	2018
30242108	NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains.	Journal of Lipid Research	2018
30320884	The regulatory roles of glycosphingolipid-enriched lipid rafts in immune systems.	FEBS Letters	2018
29747813	Biology of GM3 Ganglioside.	Progress in Molecular Biology and Translational Science	2018
28275055	Altered expression of ganglioside GM3 molecular species and a potential regulatory role during myoblast differentiation.	J Biol Chem	2017
28808804	Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase).	Glycoconjugate Journal	2017
28709807	Identification of a new B4GalNAcT1 (GM2/GD2/GA2 synthase) isoform, and regulation of enzyme stability and intracellular transport by arginine-based motif.	Biochimica et Biophysica Acta - Biomembranes	2017
28571946	Gangliosides and hearing.	Biochimica et Biophysica Acta - General Subjects	2017
27865938	PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.	Experimental Cell Research	2017
26650179	Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.	Journal of Clinical Investigation	2016
27170180	Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow.	Molecular Biology of the Cell	2016
25193136	Distinct selectivity of gangliosides required for CD4âº T and CD8âº T cell activation.		2015
25652401	Ganglioside GM3 is essential for the structural integrity and function of cochlear hair cells.	Human Molecular Genetics	2015
25303960	Control of homeostatic and pathogenic balance in adipose tissue by ganglioside GM3.	Glycobiology	2015
25969421	Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment.	Progress in Lipid Research	2015
26362868	The regulation of ER export and Golgi retention of ST3Gal5 (GM3/GM4 synthase) and B4GalNAcT1 (GM2/GD2/GA2 synthase) by arginine/lysine-based motif adjacent to the transmembrane domain.	Glycobiology	2015
26638624	[Physiological significance of distinct expression of gangIioside moleculer species as bioactive lipids].	Seikagaku. The Journal of Japanese Biochemical Society	2015
26102277	Identification of Ganglioside GM3 Molecular Species in Human Serum Associated with Risk Factors of Metabolic Syndrome.	PLoS ONE	2015
24875539	Loss of hydroxyl groups from the ceramide moiety can modify the lateral diffusion of membrane proteins in S. cerevisiae.	Journal of Lipid Research	2014
23999868	Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells.	Glycoconjugate Journal	2014
24399479	GM3 and diabetes.	Glycoconjugate Journal	2014
24699373	Functional mapping and implications of substrate specificity of the yeast high-affinity leucine permease Bap2.		2014
25151375	Synthesis of o-linked glycoconjugates in the nervous system.	Advances in neurobiology	2014