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Author Details

Shengkan Jin
Robert Wood Johnson Medical School
1998
50
40
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33616445Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System.CRISPR J2021
33649533Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models.Oncogene2021
28780747Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice.Eat Weight Disord2019
29440715Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer.Cell Death Dis2018
28093935New methods for monitoring mitochondrial biogenesis and mitophagy in vitro and in vivo.Exp Biol Med (Maywood)2017
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
26983466A role for ABCG2 beyond drug transport: Regulation of autophagy.Autophagy2016
24166374The bioluminescent imaging of spontaneously occurring tumors in immunocompetent ODD-luciferase bearing transgenic mice.Methods Mol Biol2014
25282357Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.Nat Med2014
22889849KCS1 deletion in Saccharomyces cerevisiae leads to a defect in translocation of autophagic proteins and reduces autophagosome formation.Autophagy2012
22966490Guidelines for the use and interpretation of assays for monitoring autophagy.Autophagy2012
23017672Autophagy in adipose tissue biology.Pharmacol Res2012
21126221Autophagic degradation of mitochondria in white adipose tissue differentiation.Antioxid Redox Signal2011
22024753Vaccinia virus leads to ATG12â¿¿ATG3 conjugation and deficiency in autophagosome formation.Autophagy2011
22118666Mitochondrial complex III: Tuner of autophagy.Chem Biol2011
21479246Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice.PLoS One2011
20083234Autophagy and the degradation of mitochondria.Mitochondrion2010
20110772Autophagy and adipogenesis: implications in obesity and type II diabetes.Autophagy2010
19187200Productive Chlamydia trachomatis lymphogranuloma venereum 434 infection in cells with augmented or inactivated autophagic activities.FEMS Microbiol Lett2009
19844159Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice.Autophagy2009
19910529Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis.Proc Natl Acad Sci U S A2009
18188003Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.Autophagy2008
28186855Tumor suppression by autophagy through the management of metabolic stress.Autophagy2008
18326941Tumor suppression by autophagy through the management of metabolic stress.Autophagy2008
16969128Role of autophagy in cancer: management of metabolic stress.Autophagy2007
17606641Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis.Genes Dev2007
17510285Autophagy suppresses tumor progression by limiting chromosomal instability.Genes Dev2007
17409411The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways.Cancer Res2007
17404498The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains.Autophagy2007
17204841Autophagy regulates ageing in C. elegans.Autophagy2007
17251378Metabolic catastrophe as a means to cancer cell death.J Cell Sci2007
16278683p53 tumor suppressor protein regulates the levels of huntingtin gene expression.Oncogene2006
17015701Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death.J Immunol2006
16843265Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.Cancer Cell2006
16874104Cellular autophagy machinery is not required for vaccinia virus replication and maturation.Autophagy2006
16874075Autophagy, mitochondrial quality control, and oncogenesis.Autophagy2006
16921268Elongation factor-2 kinase: its role in protein synthesis and autophagy.Autophagy2006
16452501Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways.Genes Dev2006
16540650Elongation factor-2 kinase regulates autophagy in human glioblastoma cells.Cancer Res2006
16609004A matter of life or death (or both): understanding autophagy in cancer.Clin Cancer Res2006
15928081The coordinate regulation of the p53 and mTOR pathways in cells.Proc Natl Acad Sci U S A2005
16874039p53, Autophagy and tumor suppression.Autophagy2005
12569127CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals.Genes Dev2003
14657337Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.Proc Natl Acad Sci U S A2003
12077306The p53MH algorithm and its application in detecting p53-responsive genes.Proc Natl Acad Sci U S A2002
11739646The p53 functional circuit.J Cell Sci2001
10644769Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1.J Biol Chem2000
10860994Identification and characterization of a p53 homologue in Drosophila melanogaster.Proc Natl Acad Sci U S A2000
10841572Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation.Proc Natl Acad Sci U S A2000
9632821Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.Mol Cell Biol1998
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Collaborators

Simons Center for Systems Biology, Institute for Advanced Study
Co-authored papers 9
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 3
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Weizmann Institute of Science
Co-authored papers 3
University Of Michigan ann arbor
Co-authored papers 3
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University of California San Francisco
Co-authored papers 3
Albert Einstein College of Medicine
Co-authored papers 3
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 3
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 3
Yale University
Co-authored papers 2
Universite de Montreal
Co-authored papers 2
CRUK MRC Oxford Institute for Radiation Oncology, University of Oxford
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Weill Cornell School of Medicine
Co-authored papers 2
University of Warwick
Co-authored papers 2
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Co-authored papers 2
Co-authored papers 2
Rutgers New Jersey Medical School
Co-authored papers 2
Co-authored papers 2
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
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University of Pennsylvania
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Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
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Harvard Medical School
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Armed Forces Radiobiology Research Institute
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Winship Cancer Institute, Emory University
Co-authored papers 2
University at Albany
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