Author details

Full Name

Yang Xu

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36929008	RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes.		2023
36546079	Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis.	Sci Bull (Beijing)	2022
33575089	P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.	American Journal of Cancer Research (discontinued)	2021
33011360	Repair of acute liver damage with immune evasive hESC derived hepato-blasts.	Stem Cell Research	2020
33242828	hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts.	eBioMedicine	2020
31145821	IDO1 Maintains Pluripotency of Primed Human Embryonic Stem Cells by Promoting Glycolysis.	Stem Cells	2019
31572807	Rapid 3D bioprinting of cardiac tissue models using human embryonic stem cell-derived cardiomyocytes.	Bioprinting	2019
30712844	Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation.	Cancer Cell	2019
28090751	A Safety Checkpoint to Eliminate Cancer Risk of the Immune Evasive Cells Derived from Human Embryonic Stem Cells.	Stem Cells	2017
28626459	The Immunogenicity and Immune Tolerance of Pluripotent Stem Cell Derivatives.	Frontiers in Immunology	2017
28334641	Humanized mouse model for assessing the human immune response to xenogeneic and allogeneic decellularized biomaterials.	Biomaterials	2017
28192772	Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture.	Biomaterials	2017
26439188	Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives.	Stem Cells	2016
26299572	Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.	Cell Stem Cell	2015
25733712	Stemness factor Sall4 is required for DNA damage response in embryonic stem cells.	Journal of Cell Biology	2015
24691905	Functional analysis of the acetylation of human p53 in DNA damage responses.	Protein and Cell	2014
24038750	Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation.	Stem Cells	2014
23770853	The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.	Oncogene	2014
24388175	An effective approach to prevent immune rejection of human ESC-derived allografts.		2014
24675459	p53 Induces skin aging by depleting Blimp1+ sebaceous gland cells.	Cell Death and Disease	2014
24622843	Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template.	Protein and Cell	2014
24749065	Mouse SCNT ESCs have lower somatic mutation load than syngeneic iPSCs.	Stem Cell Reports	2014
24044867	Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3.	J Med Chem	2013
22824795	The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.	Oncogene	2013
22023807	Proteome-wide detection of Abl1 SH3-binding peptides by integrating computational prediction and peptide microarray.	Mol Cell Proteomics	2012
25408868	Progress and bottleneck in induced pluripotency.	Cell Regeneration	2012
22741526	Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability.	Genome Medicine	2012
22425986	Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells.	Biochemical and Biophysical Research Communications	2012
22730289	Global identification of transcriptional regulators of pluripotency and differentiation in embryonic stem cells.	Nucleic Acids Res	2012
22528751	The genomic stability of induced pluripotent stem cells.	Protein and Cell	2012
22865887	A scalable approach to prevent teratoma formation of human embryonic stem cells.	Journal of Biological Chemistry	2012
23010077	Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer.	Cancer Research	2012
22311782	Context-dependent enhancement of induced pluripotent stem cell reprogramming by silencing Puma.	Stem Cells	2012
21548738	Self-renewal and scalability of human embryonic stem cells for human therapy.	Regenerative Medicine	2011
21050134	p53, oxidative stress, and aging.	Antioxidants and Redox Signaling	2011
21852242	Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of Î²-cells from human pluripotent stem cells.	Journal of Biological Chemistry	2011
21572395	Immunogenicity of induced pluripotent stem cells.	Nature	2011
20018659	A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells.	Proc Natl Acad Sci U S A	2010
20818388	Puma is required for p53-induced depletion of adult stem cells.	Nature Cell Biology	2010
20622153	Phosphorylation stabilizes Nanog by promoting its interaction with Pin1.	Proceedings of the National Academy of Sciences of the United States of America	2010
20074536	Modeling disease in human ESCs using an efficient BAC-based homologous recombination system.		2010
19966290	Role of the translocation partner in protection against AID-dependent chromosomal translocations.	Proc Natl Acad Sci U S A	2010
19881536	A common gain of function of p53 cancer mutants in inducing genetic instability.	Oncogene	2010
20198346	Synergistic antineoplastic effect of DLC1 tumor suppressor protein and histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), on prostate and liver cancer cells: perspectives for therapeutics.	International Journal of Oncology	2010
20061153	p53 and stem cells: new developments and new concerns.	Trends in Cell Biology	2010
20587338	Disease research and drug development models based on genetically altered human embryonic stem cells.		2010
18923442	DLC1 tumor suppressor gene inhibits migration and invasion of multiple myeloma cells through RhoA GTPase pathway.	Leukemia	2009
19023120	Characterization of domain-peptide interaction interface: a generic structure-based model to decipher the binding specificity of SH3 domains.	Mol Cell Proteomics	2009
19151751	p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities.	Oncogene	2009
19767771	Transcription activity is required for p53-dependent tumor suppression.	Oncogene	2009