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Author Details

Thorsten Berger
Princess Margaret Cancer Centre, University Health Network
1998
59
32
PMIDPaper TitleJournal TitlePublished Year
36736318IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.Cancer Cell2023
37729199HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma.Proc Natl Acad Sci U S A2023
37640929Tumor-specific cholinergic CD4<sup>+</sup> T lymphocytes guide immunosurveillance of hepatocellular carcinoma.Nat Cancer2023
37493438Identification of an Optimized Receptor-Binding Domain Subunit Vaccine against SARS-CoV-2.J Immunol2023
36652477Distinct and opposite effects of leukemogenic <i>Idh</i> and <i>Tet2</i> mutations in hematopoietic stem and progenitor cells.Proc Natl Acad Sci U S A2023
33254233IDH1 mutation contributes to myeloid dysplasia in mice by disturbing heme biosynthesis and erythropoiesis.Blood2021
33686237Beyond immune checkpoint blockade: emerging immunological strategies.Nat Rev Drug Discov2021
31033725Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated lipocalin expression upon mineralocorticoid receptor activation.J Hypertens2019
31552301Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.Commun Biol2019
30770442Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.Proc Natl Acad Sci U S A2019
30733420Choline acetyltransferase-expressing T cells are required to control chronic viral infection.Science2019
30733286AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.Proc Natl Acad Sci U S A2019
29378951Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.Proc Natl Acad Sci U S A2018
30257107Loss of the adipokine lipocalin-2 impairs satellite cell activation and skeletal muscle regeneration.Am J Physiol Cell Physiol2018
30517895Parasitic Behavior of Leukemic Cells in Systemic Host Metabolism.Cell Metab2018
29444358A Complex Role for Lipocalin 2 in Bone Metabolism: Global Ablation in Mice Induces Osteopenia Caused by an Altered Energy Metabolism.J Bone Miner Res2018
27800610Lipocalin-2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia.J Cell Physiol2017
28349107Data on IL-10R neutralization-induced chronic colitis in Lipocalin 2 deficient mice on BALB/c background.Data Brief2017
28396286Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis.Biochim Biophys Acta Mol Basis Dis2017
29234288Lipocalin-2 in Fructose-Induced Fatty Liver Disease.Front Physiol2017
28670364Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge.Am J Transl Res2017
27229458Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice.Cardiovasc Res2016
28057846Beyond the Oncogene Revolution: Four New Ways to Combat Cancer.Cold Spring Harb Symp Quant Biol2016
25234944Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3.Hepatology2015
25833847Caspase functions in cell death and disease.Cold Spring Harb Perspect Biol2015
25987661Neutrophil Gelatinase-Associated Lipocalin, a Novel Mineralocorticoid Biotarget, Mediates Vascular Profibrotic Effects of Mineralocorticoids.Hypertension2015
25620030Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.Cancer Cell2015
24465207Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.PLoS Pathog2014
25257511Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response.Aging Cell2014
25011565Development and characterization of a new inbred transgenic rat strain expressing DsRed monomeric fluorescent protein.Transgenic Res2014
25086218Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver.Biochim Biophys Acta2014
24803661Lipocalin 2 binds to membrane phosphatidylethanolamine to induce lipid raft movement in a PKA-dependent manner and modulates sperm maturation.Development2014
22614012Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression.Oncogene2013
25028400Dissection of signaling in inflammation: three novel inflammatory regulators.Cold Spring Harb Symp Quant Biol2013
23545416Caspase functions in cell death and disease.Cold Spring Harb Perspect Biol2013
23219901Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions.J Proteomics2013
23376114Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis.Biochim Biophys Acta2013
23146906Flotillin-2 deficiency leads to reduced lung metastases in a mouse breast cancer model.Oncogene2013
21740414Lipocalin-2 deficiency prevents endothelial dysfunction associated with dietary obesity: role of cytochrome P450 2C inhibition.Br J Pharmacol2012
23185529Lipocalin 2 regulates inflammation during pulmonary mycobacterial infections.PLoS One2012
23272119Prophylactic valproic acid treatment prevents schizophrenia-related behaviour in Disc1-L100P mutant mice.PLoS One2012
22246778iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.Science2012
22355443Improved functional recovery to I/R injury in hearts from lipocalin-2 deficiency mice: restoration of mitochondrial function and phospholipids remodeling.Am J Transl Res2012
22083497Neutrophil gelatinase-associated lipocalin is instrumental in the pathogenesis of antibody-mediated nephritis in mice.Arthritis Rheum2012
20068130Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity.Diabetes2010
20921623Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.J Clin Invest2010
20543135Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors.Proc Natl Acad Sci U S A2010
20133630Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis.Proc Natl Acad Sci U S A2010
19454351Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine.Cell Host Microbe2009
19342674Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.J Immunol2009
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Collaborators

Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 51
Andrew Wakeham
Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network
Co-authored papers 12
Andrew J Elia
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 8
Matthias Kretzler
University of Michigan ann arbor
Co-authored papers 5
Detlef Schl??ndorff
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
David W Cescon
Princess Margaret Cancer Centre
Co-authored papers 3
Chiara Gorrini
Division of Clinical Studies, The Institute of Cancer Research
Co-authored papers 3
Paola Cappello
University of Turin
Co-authored papers 2
Rama Khokha
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Cem Meydan
Co-authored papers 2
Christopher E Mason
Feil Family Brain and Mind Research Institute.
Co-authored papers 2
Jonathan Foox
Co-authored papers 2
Ari Melnick
Co-authored papers 2
Helmut E Meyer
Co-authored papers 2
Clemens D Cohen
Medical Clinic and Policlinic IV, University of Munich
Co-authored papers 2
Hal K Berman
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 1
Natalie C J Strynadka
The University of British Columbia
Co-authored papers 1
Frank Tacke
Charite-Universitatsmedizin Berlin
Co-authored papers 1
Albert H C Wong
Campbell Family Mental Health Research Institute
Co-authored papers 1
David B Thomas
Duke University
Co-authored papers 1
John C Roder
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 1
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Jacqueline M Mason
Campbell Family Institute for Breast Cancer Research, University Health Network
Co-authored papers 1
Susan J Done
University Health Network
Co-authored papers 1
Fahmida Nipa Haque
University of Toronto
Co-authored papers 1
Mario A Ostrowski
Co-authored papers 1
Alexander McGirr
University of Calgary
Co-authored papers 1
Chaim Putterman
Albert Einstein College of Medicine
Co-authored papers 1
Release 1.2