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Author Details

Rakesh K Jain
Massachusetts General Hospital, Harvard Medical School
1978
850
181
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35969170Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy.Clin Cancer Res2023
37010875Multicenter, prospective, phase II study of maintenance bevacizumab for children and adults with NF2-related schwannomatosis and progressive vestibular schwannoma.Neuro Oncol2023
36749873Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer.Clin Cancer Res2023
36747853Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy.bioRxiv2023
36831366Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models.Cancers (Basel)2023
36898734Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice.J Immunother Cancer2023
33431577Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.Gut2022
35584239Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition.Clin Cancer Res2022
35614012Impact of renin-angiotensin system inhibitors on outcomes in patients with metastatic renal cell carcinoma treated with immune-checkpoint inhibitors.Clin Genitourin Cancer2022
35833850A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.Clin Cancer Res2022
35714604The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy.Cancer Cell2022
36245248Revisiting Antiangiogenic Multikinase Inhibitors in the Era of Immune Checkpoint Blockade: The Case of Sorafenib.Cancer Res2022
35902743Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.Nat Genet2022
35318369Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction.Sci Rep2022
35288743Increased CD8+ T-cell Infiltration and Efficacy for Multikinase Inhibitors After PD-1 Blockade in Hepatocellular Carcinoma.J Natl Cancer Inst2022
35065368Renin-angiotensin-aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors.Eur J Cancer2022
35033853Strategies to minimize heterogeneity and optimize clinical trials in Acute Respiratory Distress Syndrome (ARDS): Insights from mathematical modelling.EBioMedicine2022
35271911Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy.J Control Release2022
33402434In silico dynamics of COVID-19 phenotypes for optimizing clinical management.Proc Natl Acad Sci U S A2021
33648989Vascular Normalization to Improve Treatment of COVID-19: Lessons from Treatment of Cancer.Clin Cancer Res2021
33534142Implications of a granulocyte-high glioblastoma microenvironment in immune suppression and therapy resistance<sup>â¿ </sup>.J Pathol2021
33839688Exercise Training Improves Tumor Control by Increasing CD8[+] T-cell Infiltration via CXCR3 Signaling and Sensitizes Breast Cancer to Immune Checkpoint Blockade.Cancer Immunol Res2021
33663521Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model.Radiat Oncol2021
34860501Kendrick Mass Defect Variation to Decipher Isotopic Labeling in Brain Metastases Studied by Mass Spectrometry Imaging.Anal Chem2021
35122065Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis.Nat Cancer2021
34732899Publisher Correction: A metastasis map of human cancer cell lines.Nature2021
34725151Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy.Proc Natl Acad Sci U S A2021
34188163Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients.NPJ Precis Oncol2021
34215680Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy.Sci Immunol2021
34179825FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS.Nat Cancer2021
34011489Angiotensin Blockade Modulates the Activity of PD1/L1 Inhibitors in Metastatic Urothelial Carcinoma.Clin Genitourin Cancer2021
34261799Losartan prevents tumor-induced hearing loss and augments radiation efficacy in NF2 schwannoma rodent models.Sci Transl Med2021
33978307Phase II and Biomarker Study of Cabozantinib in Metastatic Triple-Negative Breast Cancer Patients.Oncologist2021
33976133Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas.Nat Commun2021
34021235Comparing machine learning algorithms for predicting ICU admission and mortality in COVID-19.NPJ Digit Med2021
33090190The Current Landscape of Immune Checkpoint Blockade in Hepatocellular Carcinoma: A Review.JAMA Oncol2021
33199490Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma.Clin Cancer Res2021
31541381A phase II study of cabozantinib alone or in combination with trastuzumab in breast cancer patients with brain metastases.Breast Cancer Res Treat2020
32015113Combining microenvironment normalization strategies to improve cancer immunotherapy.Proc Natl Acad Sci U S A2020
32042168Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy.Nat Biotechnol2020
31679081Vessel co-option in glioblastoma: emerging insights and opportunities.Angiogenesis2020
32034288Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges.Nat Rev Clin Oncol2020
31879345CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas.Proc Natl Acad Sci U S A2020
33299191A metastasis map of human cancer cell lines.Nature2020
33235308Author Correction: Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin.Nat Biomed Eng2020
33234602Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma.J Immunother Cancer2020
33122355Physical traits of cancer.Science2020
33036972NAD<sup>+</sup>-mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior.Sci Adv2020
32572196Non-invasive monitoring of chronic liver disease via near-infrared and shortwave-infrared imaging of endogenous lipofuscin.Nat Biomed Eng2020
32681151In vivo compression and imaging in mouse brain to measure the effects of solid stress.Nat Protoc2020
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Collaborators

Brigham and Women's Hospital
Co-authored papers 39
Co-authored papers 20
Massachusetts General Hospital
Co-authored papers 17
Institut Curie, INSERM U1, CNRS UMR3347, University Paris-Saclay
Co-authored papers 15
Oslo University Hospital
Co-authored papers 14
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 11
University of Lausanne
Co-authored papers 11
University Health Network
Co-authored papers 10
Co-authored papers 10
Massachusetts General Hospital
Co-authored papers 8
Massachusetts General Hospital
Co-authored papers 7
Co-authored papers 7
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital
Co-authored papers 6
Center for Computational and Integrative Biology, Massachusetts General Hospital
Co-authored papers 6
Co-authored papers 6
Weizmann Institute of Science
Co-authored papers 6
Dana-Farber Cancer Institute
Co-authored papers 5
Co-authored papers 5
Duke School of Medicine
Co-authored papers 5
Harvard Medical School
Co-authored papers 4
Co-authored papers 4
Dana-Farber Cancer Institute
Co-authored papers 4
Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital
Co-authored papers 4
Massachusetts General Hospital
Co-authored papers 4
Macquarie University
Co-authored papers 4
Broad Institute of MIT and Harvard
Co-authored papers 4
Broad Institute of MIT and Harvard
Co-authored papers 4
Co-authored papers 3
Nencki Institute of Experimental Biology of Polish Academy of Sciences
Co-authored papers 3
Ontario Brain Institute
Co-authored papers 3