Author details

Full Name

Choukri Ben Mamoun

Affiliation

ORCID

Career Start Year

1996

Papers

110

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37055610	Babesia duncani multi-omics identifies virulence factors and drug targets.	Nat Microbiol	2023
38045341	A Potent Kalihinol Analogue Disrupts Apicoplast Function and Vesicular Trafficking in Malaria.		2023
37797695	Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril.	J Biol Chem	2023
36698187	FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species.		2023
37068249	The human malaria parasite can sense environmental changes and respond by antigenic switching.		2023
36997087	Maturation of the malarial phosphatidylserine decarboxylase is mediated by high affinity binding to anionic phospholipids.		2023
35041826	Redesigning therapies for pantothenate kinase-associated neurodegeneration.	Journal of Biological Chemistry	2022
36040206	Specific and Sensitive Diagnosis of Babesia microti Active Infection Using Monoclonal Antibodies to the Immunodominant Antigen BmGPI12.	Journal of Clinical Microbiology	2022
35512141	Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo.	Journal of Infectious Diseases	2022
36167065	High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development.	Structure	2022
35631120	An Alternative Culture Medium for Continuous In Vitro Propagation of the Human Pathogen in Human Erythrocytes.	Pathogens	2022
36506011	Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen .		2022
36620533	in Culture and in Mouse (ICIM) Model for the Advancement of Biology, Pathogenesis, and Therapy.		2022
36613877	Evidence for a Conserved Function of Eukaryotic Pantothenate Kinases in the Regulation of Mitochondrial Homeostasis and Oxidative Stress.		2022
34139755	Cytochrome b Drug Resistance Mutation Decreases Babesia Fitness in the Tick Stages But Not the Mammalian Erythrocytic Cycle.	Journal of Infectious Diseases	2022
34485323	Recent Progress in Lyme Disease and Remaining Challenges.	Front Med (Lausanne)	2021
35373072	Evidence for SARS-CoV-2 Spike Protein in the Urine of COVID-19 Patients.	Kidney360	2021
34152821	Effective Therapy Targeting Cytochrome Prevents Erythrocytic Development and Protects from Lethal Infection.	Antimicrobial Agents and Chemotherapy	2021
34140472	Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.	Nat Commun	2021
34578153	Treatment of Human Babesiosis: Then and Now.	Pathogens	2021
32158750	Efficient Single-Gene and Gene Family Editing in the Apicomplexan Parasite Using CRISPR-Cas9.	Frontiers in Bioengineering and Biotechnology	2020
32430397	An improved and highly selective fluorescence assay for measuring phosphatidylserine decarboxylase activity.	Journal of Biological Chemistry	2020
32427965	Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria.	Nature	2020
32342554	Palmitoylated Proteins in Plasmodium falciparum-Infected Erythrocytes: Investigation with Click Chemistry and Metabolic Labeling.	BioEssays	2020
30827459	Inaugural meeting of the international babesiosis research community, 2018: A glimpse into the future of an emerging research field.	International Journal for Parasitology	2019
31585506	Crystal structures of lactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis.	FASEB Journal	2019
30367868	A library of recombinant Babesia microti cell surface and secreted proteins for diagnostics discovery and reverse vaccinology.	International Journal for Parasitology	2019
30367862	Evidence for transmission of the zoonotic apicomplexan parasite Babesia duncani by the tick Dermacentor albipictus.	International Journal for Parasitology	2019
30658178	Stable transfection of Eimeria necatrix through nucleofection of second generation merozoites.	Molecular and Biochemical Parasitology	2019
30176236	Insights into the evolution and drug susceptibility of Babesia duncani from the sequence of its mitochondrial and apicoplast genomes.	International Journal for Parasitology	2019
31227523	High-throughput screening for phosphatidylserine decarboxylase inhibitors using a distyrylbenzene-bis-aldehyde (DSB-3)-based fluorescence assay.	Journal of Biological Chemistry	2019
30694415	Selection and identification of a precocious line of Eimeria intestinalis with enlarged oocysts and deletion of one generation of schizogony.	Parasitology Research	2019
30723152	Comparative 3D genome organization in apicomplexan parasites.	Proc Natl Acad Sci U S A	2019
31196872	Evidence for vesicle-mediated antigen export by the human pathogen .	Life Science Alliance	2019
31409644	The yeast pantothenate kinase Cab1 is a master regulator of sterol metabolism and of susceptibility to ergosterol biosynthesis inhibitors.	Journal of Biological Chemistry	2019
29247006	A novel fluorescence assay for measuring phosphatidylserine decarboxylase catalysis.	Journal of Biological Chemistry	2018
30093394	BmGPAC, an Antigen Capture Assay for Detection of Active Babesia microti Infection.	Journal of Clinical Microbiology	2018
30287688	Role of phospholipid synthesis in the development and differentiation of malaria parasites in the blood.	Journal of Biological Chemistry	2018
30463941	Establishment of a continuous culture of in human erythrocytes reveals unusually high tolerance to recommended therapies.	Journal of Biological Chemistry	2018
29673170	Cysteine Proteinase C1A Paralog Profiles Correspond with Phylogenetic Lineages of Pathogenic Piroplasmids.	Veterinary Sciences	2018
29394381	Case report of the patient source of the Babesia microti R1 reference strain and implications for travelers.	Journal of Travel Medicine	2018
27919897	Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii.	Antimicrobial Agents and Chemotherapy	2017
28959410	A complex stereochemical relay approach to the antimalarial alkaloid ocimicide A. Evidence for a structural revision.	Chemical Science	2017
28337330	Antimalarial Properties of Simplified Kalihinol Analogues.	ACS Medicinal Chemistry Letters	2017
29258508	Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia.	Malar J	2017
29079738	The antimalarial activity of the pantothenamide Î±-PanAm is via inhibition of pantothenate phosphorylation.	Scientific Reports	2017
27821055	Babesia microti from humans and ticks hold a genomic signature of strong population structure in the United States.	BMC Genomics	2016
26744270	Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures.	BMC Genomics	2016
27184823	A targeted immunomic approach identifies diagnostic antigens in the human pathogen Babesia microti.	Transfusion	2016
27270894	Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.	Journal of Experimental Medicine	2016