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Author Details

Zachary Goodman
Center for Liver Diseases, Inova Fairfax Hospital
1975
277
93
PMIDPaper TitleJournal TitlePublished Year
37088457Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study.Clin Gastroenterol Hepatol2024
37088458Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Compensated Cirrhosis (FALCON 2): A Randomized Phase 2b Study.Clin Gastroenterol Hepatol2024
35074532Performance of Noninvasive Tests of Fibrosis Among Asians, Hispanic, and non-Hispanic Whites in the STELLAR Trials.Clin Gastroenterol Hepatol2023
37024212Role of Liver Biopsy in Clinical Trials and Clinical Management of Nonalcoholic Fatty Liver Disease.Clin Liver Dis2023
36967586The combination of the enhanced liver fibrosis and FIB-4 scores to determine significant fibrosis in patients with nonalcoholic fatty liver disease.Aliment Pharmacol Ther2023
36922785PRIMIS: design of a pivotal, randomized, phase 3 study evaluating the safety and efficacy of the nonsteroidal farnesoid X receptor agonist cilofexor in noncirrhotic patients with primary sclerosing cholangitis.BMC Gastroenterol2023
36750244Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis.Gut2023
36647687Machine learning liver histology scores correlate with portal hypertension assessments in nonalcoholic steatohepatitis cirrhosis.Aliment Pharmacol Ther2023
36797481Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial.Nat Med2023
34662449Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis.Hepatology2022
35384259An MMP-degraded and cross-linked fragment of type III collagen as a non-invasive biomarker of hepatic fibrosis resolution.Liver Int2022
35090960Complexity of ballooned hepatocyte feature recognition: Defining a training atlas for artificial intelligence-based imaging in NAFLD.J Hepatol2022
35194091Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis.Sci Rep2022
34793868Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study.J Hepatol2022
34605045BMS-986263 in patients with advanced hepatic fibrosis: 36-week results from a randomized, placebo-controlled phase 2 trial.Hepatology2022
32544255From NAFLD to MAFLD: Implications of a Premature Change in Terminology.Hepatology2021
33570776A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.Hepatology2021
33616848Performance of Noninvasive Liver Fibrosis Tests in Morbidly Obese Patients with Nonalcoholic Fatty Liver Disease.Obes Surg2021
33657443The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis.Contemp Clin Trials2021
34454994Comparison of ADAPT, FIB-4 and APRI as non-invasive predictors of liver fibrosis and NASH within the CENTAUR screening population.J Hepatol2021
34333790A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis.Hepatology2021
34278169Improvements of Fibrosis and Disease Activity Are Associated With Improvement of Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis.Hepatol Commun2021
33169409Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH.Hepatology2021
33164276Multicenter, Double-Blind, Randomized Trial of Emricasan in Hepatitis C-Treated Liver Transplant Recipients With Residual Fibrosis or Cirrhosis.Liver Transpl2021
32607686Fifty years of impact on liver pathology: a history of the Gnomes.Virchows Arch2021
32745270A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis.Hepatology2021
32707342Inter- and Intra-individual Variation, and Limited Prognostic Utility, of Serum Alkaline Phosphatase in a Trial of Patients With Primary Sclerosing Cholangitis.Clin Gastroenterol Hepatol2021
32150543Association of novel markers of liver disease with neonatal liver disease in premature baboons, Papio sp.PLoS One2020
31887369A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis.J Hepatol2020
31943293Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.Hepatology2020
31881392Cenicriviroc for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis: AURORA Phase 3 study design.Contemp Clin Trials2020
33163834Fatigue and Pruritus in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: The Impact on Patient-Reported Outcomes.Hepatol Commun2020
33437901Major Histocompatibility Complex Class I-Related Chain A Alleles and Histology of Nonalcoholic Fatty Liver Disease.Hepatol Commun2020
32923831Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.Hepatol Commun2020
30291868Longitudinal correlations between MRE, MRI-PDFF, and liver histology in patients with non-alcoholic steatohepatitis: Analysis of data from a phase II trial of selonsertib.J Hepatol2019
31813633Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.Lancet2019
32039401Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.JHEP Rep2019
30160980Assessment of liver fibrosis progression and regression by a serological collagen turnover profile.Am J Physiol Gastrointest Liver Physiol2019
30153359Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease.Hepatology2019
31271665Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials.Hepatology2019
31260793REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis.Contemp Clin Trials2019
31393374Analysis of human leukocyte antigen allele polymorphism in patients with non alcoholic fatty liver disease.Medicine (Baltimore)2019
30744560Hepatic sonic hedgehog protein expression measured by computer assisted morphometry significantly correlates with features of non-alcoholic steatohepatitis.BMC Gastroenterol2019
30993748The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials.Hepatology2019
28892558The ASK1 inhibitor selonsertib in patients with nonalcoholic steatohepatitis: A randomized, phase 2 trial.Hepatology2018
30075518Liver Transplantation (LT) for Cryptogenic Cirrhosis (CC) and Nonalcoholic Steatohepatitis (NASH) Cirrhosis: Data from the Scientific Registry of Transplant Recipients (SRTR): 1994 to 2016.Medicine (Baltimore)2018
29990488Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis.Gastroenterology2018
30205811An exploratory study examining how nano-liquid chromatography-mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease.BMC Med2018
30144554The conundrum of cryptogenic cirrhosis: Adverse outcomes without treatment options.J Hepatol2018
29928018Polymorphisms in the receptor for advanced glycation end-products (RAGE) gene and circulating RAGE levels as a susceptibility factor for non-alcoholic steatohepatitis (NASH).PLoS One2018
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Collaborators

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John Hunter Children's Hospital
Co-authored papers 14
University Clinic for Visceral Surgery and Medicine, Bern University
Co-authored papers 8
University of California San Francisco
Co-authored papers 5
University of Queensland
Co-authored papers 5
Inc.Foster CityCA.
Co-authored papers 3
Center for Applied Proteomics and Molecular Medicine, George Mason University
Co-authored papers 3
University of California at San Francisco
Co-authored papers 3
Johns Hopkins University School of Medicine
Co-authored papers 3
Scripps Clinic and Scripps Translational Science Institute
Co-authored papers 3
Charite-Universitatsmedizin Berlin
Co-authored papers 3
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 3
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 2
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Ann & Robert H. Lurie Children's Hospital of Chicago
Co-authored papers 2
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
University of Colorado Denver
Co-authored papers 2
Mie University Graduate School of Medicine
Co-authored papers 2
University of Washington
Co-authored papers 2
The University of Melbourne at the Peter Doherty Institute for Infection and Immunity
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Eshelman School of Pharmacy, University of North Carolina
Co-authored papers 1
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Department of Pharmacy, Liyang People's Hospital
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 1