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Author Details

Jinrong Min
Central China Normal University
1994
138
50
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37263341N/C-degron pathways and inhibitor development for PROTAC applications.Biochim Biophys Acta Gene Regul Mech2024
37409559Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors.Nucleic Acids Res2023
38045046A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.Acta Pharm Sin B2023
37086783Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.J Biol Chem2023
34782742A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.Nat Chem Biol2022
36056043Structural basis for Gemin5 decamer-mediated mRNA binding.Nat Commun2022
36350514Proteins That Read DNA Methylation.Adv Exp Med Biol2022
36114190A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.Nat Commun2022
35074427Structural basis for the recognition of methylated histone H3 by the Arabidopsis LHP1 chromodomain.J Biol Chem2022
34919920Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.J Mol Biol2022
35119221Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons.Adv Sci (Weinh)2022
34897689Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.FEBS Lett2022
33398170Molecular basis for ubiquitin ligase CRL2<sup>FEM1C</sup>-mediated recognition of C-degron.Nat Chem Biol2021
33522809Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.J Med Chem2021
33823458Structures of chromatin modulators in complex with nucleosome.Curr Opin Chem Biol2021
33649600Reply to: Binding site for MDL-801 on SIRT6.Nat Chem Biol2021
33556623Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.Biochim Biophys Acta Gene Regul Mech2021
34715126Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.J Biol Chem2021
34077206Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.J Med Chem2021
34271259Histone and DNA binding ability studies of the NSD subfamily of PWWP domains.Biochem Biophys Res Commun2021
31288074Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1.Methods2020
33054974Correction: A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.Elife2020
33077812Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.Commun Biol2020
33438817Large-scale survey and database of high affinity ligands for peptide recognition modules.Mol Syst Biol2020
32689795Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.J Med Chem2020
32605369Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues.J Med Chem2020
32939018Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.Commun Biol2020
32766792LOTUS domain is a novel class of G-rich and G-quadruplex RNA binding domain.Nucleic Acids Res2020
32470319Structural Basis for the Binding Selectivity of Human CDY Chromodomains.Cell Chem Biol2020
32513738Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.Proc Natl Acad Sci U S A2020
31626811Structural Basis for the Recognition of Non-methylated DNA by the CXXC Domain.J Mol Biol2020
30471255Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.J Mol Biol2019
31657716A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.Elife2019
31327677Identification and characterization of the first fragment hits for SETDB1 Tudor domain.Bioorg Med Chem2019
31504794LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.Nucleic Acids Res2019
31046474Structure and function of eTudor domain containing TDRD proteins.Crit Rev Biochem Mol Biol2019
30842648Addendum: A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.Nat Chem Biol2019
30980593Structural analyses reveal that MBD3 is a methylated CG binder.FEBS J2019
30976796Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system.Nucleic Acids Res2019
31054975Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins.Mol Cell2019
30785395Structural insights into SETD3-mediated histidine methylation on β-actin.Elife2019
30604749Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.Nat Commun2019
29276034DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.Structure2018
30374165Identification of a cellularly active SIRT6 allosteric activator.Nat Chem Biol2018
30417120An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.Commun Biol2018
29494751Structural and histone binding studies of the chromo barrel domain of TIP60.FEBS Lett2018
29632410Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.Nat Chem Biol2018
29567833Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.J Biol Chem2018
29563185Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.Genes Dev2018
28864533First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.Proc Natl Acad Sci U S A2017
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Collaborators

Cheryl H Arrowsmith
University of Toronto
Co-authored papers 19
Heng Zhang
University of Toronto
Co-authored papers 6
Tony Pawson
Co-authored papers 5
Zuyao Ni
University of Toronto, College Street
Co-authored papers 5
Alexey Bochkarev
University of Toronto
Co-authored papers 5
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 5
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 5
Dalia Barsyte-Lovejoy
University of Toronto, College St
Co-authored papers 5
Timothy R Hughes
University of Toronto
Co-authored papers 4
Ally Yang
University of Toronto
Co-authored papers 4
Hualiang Jiang
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Co-authored papers 3
Haiteng Deng
Co-authored papers 3
Yuzhe Zhang
China University of Mining and Technology
Co-authored papers 3
Xinghua Guo
University of Toronto, College Street
Co-authored papers 3
Yufeng Tong
University of Windsor
Co-authored papers 3
Alexei Savchenko
University of Toronto
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Gary D Bader
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Co-authored papers 2
Jenny Xiang
Caryl and Israel Englander Institute for Precision Medicine.
Co-authored papers 2
Zhike Lu
Center for Genome Editing
Co-authored papers 2
Raymond Hui
University of Toronto
Co-authored papers 2
Tuo Zhang
Weill Cornell Medical College.
Co-authored papers 2
Guoqing Zhong
University of Toronto
Co-authored papers 2
Bryan L Roth
UNC Chapel Hill School of Medicine
Co-authored papers 2
Xi-Ping Huang
University of North Carolina School of Medicine
Co-authored papers 2
Chuan He
Institute of Hematology, West China Hospital of Sichuan University
Co-authored papers 2
Rima Al-Awar
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 2
Jason Moffat
University of Toronto
Co-authored papers 1
David Baker
University of Washington
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Elena Evdokimova
University of Toronto
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Release 1.2