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Author Details

Abbot F Clark
North Texas Eye Research Institute, University of North Texas Health Science Center
1979
234
63
PMIDPaper TitleJournal TitlePublished Year
37558962Viral Vector-Induced Ocular Hypertension in Mice.Methods Mol Biol2023
35129590Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.Invest Ophthalmol Vis Sci2022
35015027Matrix Mechanotransduction via Yes-Associated Protein in Human Lamina Cribrosa Cells in Glaucoma.Invest Ophthalmol Vis Sci2022
34201109Mirna Expression in Glaucomatous and TGFβ2 Treated Lamina Cribrosa Cells.Int J Mol Sci2021
33705750The Canonical Wnt Signaling Pathway Inhibits the Glucocorticoid Receptor Signaling Pathway in the Trabecular Meshwork.Am J Pathol2021
33938911ID1 and ID3 are Negative Regulators of TGFβ2-Induced Ocular Hypertension and Compromised Aqueous Humor Outflow Facility in Mice.Invest Ophthalmol Vis Sci2021
31557521Inducible rodent models of glaucoma.Prog Retin Eye Res2020
33375386Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.J Clin Med2020
33137197Reduced Oxidative Phosphorylation and Increased Glycolysis in Human Glaucoma Lamina Cribrosa Cells.Invest Ophthalmol Vis Sci2020
32854767CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma.Mol Neurodegener2020
32522476Isolation and characterization of human optic nerve head astrocytes and lamina cribrosa cells.Exp Eye Res2020
32377644Community-Based Eye Health Screening Study in the Elderly Hispanic Population in North Texas.Tex Public Health J2020
28478122RE: "Letter to the Editor concerning Webber et al. Exp Eye Res. 148:97-102, 2016".Exp Eye Res2019
31211954Effect of ocular hypertension on the pattern of retinal ganglion cell subtype loss in a mouse model of early-onset glaucoma.Exp Eye Res2019
31050723Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma.Invest Ophthalmol Vis Sci2019
29339763Glucocorticoid receptor GRβ regulates glucocorticoid-induced ocular hypertension in mice.Sci Rep2018
29801150BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork.Invest Ophthalmol Vis Sci2018
30117188Histological investigation of human glaucomatous eyes: Extracellular fibrotic changes and galectin 3 expression in the trabecular meshwork and optic nerve head.Clin Anat2018
30062056Subtype-specific response of retinal ganglion cells to optic nerve crush.Cell Death Discov2018
30006274Establishment of a conditionally immortalized mouse optic nerve astrocyte line.Exp Eye Res2018
29392327Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells.Invest Ophthalmol Vis Sci2018
29526795Consensus recommendations for trabecular meshwork cell isolation, characterization and culture.Exp Eye Res2018
29411011Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma.Invest Ophthalmol Vis Sci2018
29625468The Role of Wnt/β-Catenin Signaling and K-Cadherin in the Regulation of Intraocular Pressure.Invest Ophthalmol Vis Sci2018
29535003Knockout of tissue transglutaminase ameliorates TGFβ2-induced ocular hypertension: A novel therapeutic target for glaucoma?Exp Eye Res2018
27443500The many faces of the trabecular meshwork cell.Exp Eye Res2017
28167045Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration.Am J Pathol2017
28159972Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells.Invest Ophthalmol Vis Sci2017
28241317TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways.Invest Ophthalmol Vis Sci2017
28346614Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork.Invest Ophthalmol Vis Sci2017
28238754Cross-linked actin networks (CLANs) in glaucoma.Exp Eye Res2017
29222550Tissue Transglutaminase Elevates Intraocular Pressure in Mice.Invest Ophthalmol Vis Sci2017
29097767Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork.Sci Rep2017
28973933CRISPR-Cas9-based treatment of myocilin-associated glaucoma.Proc Natl Acad Sci U S A2017
28822760Anterior chamber perfusion versus posterior chamber perfusion does not influence measurement of aqueous outflow facility in living mice by constant flow infusion.Exp Eye Res2017
28603016Rapid repeatable in vivo detection of retinal reactive oxygen species.Exp Eye Res2017
28068412A Comparison of Gene Expression Profiles between Glucocorticoid Responder and Non-Responder Bovine Trabecular Meshwork Cells Using RNA Sequencing.PLoS One2017
27098079In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells.Mol Neurodegener2016
26253011Introduction to EER Special Issue on ocular fibrosis.Exp Eye Res2016
27124111Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells.PLoS One2016
27300643Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells.J Glaucoma2016
27167365Identification and localization of lamina cribrosa cells in the human optic nerve head.Exp Eye Res2016
27167364Human trabecular meshwork cells express BMP antagonist mRNAs and proteins.Exp Eye Res2016
27403998HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork.Invest Ophthalmol Vis Sci2016
27373575[Novel therapeutic targets for reduction of intraocular pressure in primary open angle glaucoma].Zhonghua Yan Ke Za Zhi2016
26773873The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation.Redox Biol2016
27091054Crosstalk between TGFβ and Wnt signaling pathways in the human trabecular meshwork.Exp Eye Res2016
27008854C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury.Mol Neurodegener2016
25795916Calcium channel blockade reduces mechanical strain-induced extracellular matrix gene response in lamina cribrosa cells.Br J Ophthalmol2015
26325415Strain and Age Effects on Aqueous Humor Dynamics in the Mouse.Invest Ophthalmol Vis Sci2015
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Collaborators

Robert J Wordinger
North Texas Eye Research Institute, University North Texas Health Science Center
Co-authored papers 58
Val C Sheffield
Carver College of Medicine, University of Iowa
Co-authored papers 18
Edwin M Stone
Carver College of Medicine, University of Iowa, USA Institute for Vision Research
Co-authored papers 17
Yang Liu
North Texas Eye Research Institute, University of North Texas Health Science Center
Co-authored papers 13
Colleen M McDowell
University of Wisconsin-Madison
Co-authored papers 11
Terry A Braun
University of Iowa
Co-authored papers 8
Tasneem P Sharma
Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine
Co-authored papers 7
Thomas L Casavant
The University of Iowa College of Nursing.
Co-authored papers 5
Robert F Mullins
the University of Iowa Carver College of Medicine
Co-authored papers 4
Gareth R Howell
Tufts University Graduate School of Biomedical Sciences
Co-authored papers 4
Neeraj Agarwal
Co-authored papers 4
Todd E Scheetz
the University of Iowa Carver College of Medicine
Co-authored papers 4
Darryl R Overby
Imperial College London
Co-authored papers 3
Anne-Marie Brun-Zinkernagel
Co-authored papers 2
Yutao Liu
Augusta University
Co-authored papers 2
Alex H Wagner
Iowa State University, Mayo Clinic, Nationwide Children's Hospital, The Ohio State University College of Medicine, University of Iowa, Washington University in Saint Louis
Co-authored papers 2
Kathryn E Bollinger
Medical College of Georgia at Augusta University
Co-authored papers 2
David A Mackey
Lions Eye Institute, University of Western Australia
Co-authored papers 2
A Jason Grundstad
Co-authored papers 2
Haiyan Gong
Boston University School of Medicine
Co-authored papers 2
Andrew J Lotery
University of Southampton
Co-authored papers 1
Andrew K Shiau
Co-authored papers 1
Beth Stevens
Co-authored papers 1
Adam P DeLuca
Institute for Vision Research, Carver College of Medicine, University of Iowa
Co-authored papers 1
Jeaneen L Andorf
Institute for Vision Research, Carver College of Medicine, University of Iowa
Co-authored papers 1
Benjamin L King
Co-authored papers 1
Louis R Pasquale
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Hao F Zhang
Northwestern University
Co-authored papers 1
Brian C Leonard
Co-authored papers 1
David M Thole
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Release 1.2