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Author Details

Mitinori Saitou
Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University
1994
151
67
PMIDPaper TitleJournal TitlePublished Year
36929479Induction of fetal meiotic oocytes from embryonic stem cells in cynomolgus monkeys.EMBO J2023
37556984Key mechanisms and in vitro reconstitution of fetal oocyte development in mammals.Curr Opin Genet Dev2023
37850882Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes.EMBO J2023
36522542Author Correction: Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.Nat Cell Biol2023
36922585Generation of functional oocytes from male mice in vitro.Nature2023
36669113Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming.Proc Natl Acad Sci U S A2023
35912849Ex vivo reconstitution of fetal oocyte development in humans and cynomolgus monkeys.EMBO J2022
35842863Optimized protocol to derive germline stem-cell-like cells from mouse pluripotent stem cells.STAR Protoc2022
35442744The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys.Sci Adv2022
35703121Nucleome programming is required for the foundation of totipotency in mammalian germline development.EMBO J2022
35603814Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cells.EMBO J2022
35879609Why it is important to study human-monkey embryonic chimeras in a dish.Nat Methods2022
35944930Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis.Life Sci Alliance2022
36252211Mesothelial fusion mediates chorioallantoic membrane formation.Philos Trans R Soc Lond B Biol Sci2022
33079185Cyclosporin A and FGF signaling support the proliferation/survival of mouse primordial germ cell-like cells in vitroâ¿ .Biol Reprod2021
33608411GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program.Life Sci Alliance2021
33831365Capturing human trophoblast development with naive pluripotent stem cells in vitro.Cell Stem Cell2021
33577794Mammalian Germ Cell Development: From Mechanism to In Vitro Reconstitution.Stem Cell Reports2021
34878831Mitochondrial DNA heteroplasmy is modulated during oocyte development propagating mutation transmission.Sci Adv2021
34793202The X chromosome dosage compensation program during the development of cynomolgus monkeys.Science2021
34591639Mammalian in vitro gametogenesis.Science2021
34496297In vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells.Cell Stem Cell2021
34731633Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells.Cell Rep2021
34413299DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency.Nat Commun2021
33990696Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro.Commun Biol2021
33979596Non-human primates as a model for human development.Stem Cell Reports2021
33951437The embryonic ontogeny of the gonadal somatic cells in mice and monkeys.Cell Rep2021
34048692ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.Stem Cell Reports2021
34048690Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.Stem Cell Reports2021
32231324Generation of human oogonia from induced pluripotent stem cells in culture.Nat Protoc2020
32054698ZGLP1 is a determinant for the oogenic fate in mice.Science2020
31724030Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeysâ¿ .Biol Reprod2020
32954504Long-term expansion with germline potential of human primordial germ cell-like cells in vitro.EMBO J2020
32321940Establishment of macaque trophoblast stem cell lines derived from cynomolgus monkey blastocysts.Sci Rep2020
30962582A symmetric toggle switch explains the onset of random X inactivation in different mammals.Nat Struct Mol Biol2019
31155364Germ cell reprogramming.Curr Top Dev Biol2019
29335530Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.Nat Cell Biol2018
29804680Induction of fetal primary oocytes and the meiotic prophase from mouse pluripotent stem cells.Methods Cell Biol2018
30237246Generation of human oogonia from induced pluripotent stem cells in vitro.Science2018
29908427Epigenome regulation during germ cell specification and development from pluripotent stem cells.Curr Opin Genet Dev2018
30256801mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility.PLoS Biol2018
29674682Author Correction: Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.Nat Cell Biol2018
28056787Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing.BMC Genomics2017
28453617Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate.Biol Reprod2017
28349944Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naïve Conversion.Sci Rep2017
29208639Reconstitution of Female Germ Cell Fate Determination and Meiotic Initiation in Mammals.Cold Spring Harb Symp Quant Biol2017
29032005Promoting In Vitro Gametogenesis Research with a Social Understanding.Trends Mol Med2017
28985527Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells.Cell Stem Cell2017
29101321Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.Nat Commun2017
28981894Principles for the regulation of multiple developmental pathways by a versatile transcriptional factor, BLIMP1.Nucleic Acids Res2017
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Collaborators

The Gurdon Institute
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University of Cambridge
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School of Clinical Medicine, University of Cambridge
Co-authored papers 5
Institut Curie, PSL Research University, CNRS UMR 5, INSERM U934
Co-authored papers 3
The Rockefeller University
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Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
The Francis Crick Institute
Co-authored papers 2
Carlsberg Laboratory, Case Western Reserve University, Johns Hopkins Medicine, Johns Hopkins School of Medicine, Johns Hopkins School of Public Health, Johns Hopkins University, National Academy of Sciences, Pennsylvania State University, Presidential Commission for the Study of Bioethical Issues
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
College of life sciences, Jiangxi Normal university
Co-authored papers 2
Co-authored papers 2
College of Life Sciences
Co-authored papers 2
Osaka University
Co-authored papers 2
the Rockefeller University
Co-authored papers 2
Center for Reproductive Science, University of California los angeles
Co-authored papers 2
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Center for iPS Cell Research and Application, Kyoto University
Co-authored papers 2
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 1
Berman Institute of Bioethics, Johns Hopkins University
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Department of Medical Ethics and Law, Peking University Health Science Center
Co-authored papers 1
Advanced Research Institute, Tokyo Medical and Dental University
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
Catalan Institution for Research and Advanced Studies (ICREA)
Co-authored papers 1
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Johns Hopkins University, Berman Institute of Bioethics
Co-authored papers 1
Barcelona Institute of Science and Technology, Spain Universitat Pompeu Fabra
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Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University
Co-authored papers 1
RIKEN Center for Integrative Medical Sciences
Co-authored papers 1