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Author Details
Full Name
Marianna Orlova
Affiliation
The Research Institute of the McGill University Health Centre
ORCID
Career Start Year
1994
Papers
60
H Index
29
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36776396
Human alveolar macrophage metabolism is compromised during <i>Mycobacterium tuberculosis</i> infection.
Front Immunol
2023
37616312
Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV.
PLoS Genet
2023
35648852
A systems biology approach identifies candidate drugs to reduce mortality in severely ill patients with COVID-19.
Sci Adv
2022
33318292
Peculiar Phenotypic and Cytotoxic Features of Pulmonary Mucosal CD8 T Cells in People Living with HIV Receiving Long-Term Antiretroviral Therapy.
J Immunol
2021
33661925
Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.
PLoS Genet
2021
34879060
Deep resequencing identifies candidate functional genes in leprosy GWAS loci.
PLoS Negl Trop Dis
2021
34473646
Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis.
J Clin Invest
2021
32421744
Family-based genome-wide association study of leprosy in Vietnam.
PLoS Pathog
2020
33038764
An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa.
EBioMedicine
2020
32776973
The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions.
PLoS Pathog
2020
32967958
HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells <i>In Vivo</i>.
J Virol
2020
31308240
Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.
Proc Natl Acad Sci U S A
2019
29359182
Mitochondrial Voltage-Dependent Anion Channel Protein Por1 Positively Regulates the Nuclear Localization of <i>Saccharomyces cerevisiae</i> AMP-Activated Protein Kinase.
mSphere
2018
30102653
HIV persistence in mucosal CD4+ T cells within the lungs of adults receiving long-term suppressive antiretroviral therapy.
AIDS
2018
30487797
Neutrophils: Innate Effectors of TB Resistance?
Front Immunol
2018
30319657
Genetic Resistance to <i>Mycobacterium tuberculosis</i> Infection and Disease.
Front Immunol
2018
28793313
Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation.
PLoS Genet
2017
28222097
A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy.
PLoS Genet
2017
28993696
An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation.
Sci Rep
2017
29201558
Human Genomics of <i>Mycobacterium tuberculosis</i> Infection and Disease.
Curr Genet Med Rep
2017
26844546
A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy.
PLoS Negl Trop Dis
2016
27219008
Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases.
PLoS Negl Trop Dis
2016
26767831
A genome-wide association study of pulmonary tuberculosis in Morocco.
Hum Genet
2016
26794678
Tuberculosis in Newborns: The Lessons of the "Lübeck Disaster" (1929-1933).
PLoS Pathog
2016
25320285
Association of TNFSF8 regulatory variants with excessive inflammatory responses but not leprosy per se.
J Infect Dis
2015
24563210
CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam.
Hum Genet
2014
24610875
Association study of genes controlling IL-12-dependent IFN-γ immunity: STAT4 alleles increase risk of pulmonary tuberculosis in Morocco.
J Infect Dis
2014
23052943
Linkage disequilibrium pattern and age-at-diagnosis are critical for replicating genetic associations across ethnic groups in leprosy.
Hum Genet
2013
24378851
Development and experimental testing of an optical micro-spectroscopic technique incorporating true line-scan excitation.
Int J Mol Sci
2013
23874223
Gene set signature of reversal reaction type I in leprosy patients.
PLoS Genet
2013
23415668
Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region.
Am J Hum Genet
2013
23548717
Host genomics and control of tuberculosis infection.
Public Health Genomics
2013
23350010
PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.
PLoS Negl Trop Dis
2013
22140226
Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae.
Eukaryot Cell
2012
23283464
Genetics of leprosy reactions: an overview.
Mem Inst Oswaldo Cruz
2012
22984114
Crohn's disease susceptibility genes are associated with leprosy in the Vietnamese population.
J Infect Dis
2012
23104570
Mitochondrial porin Por1 and its homolog Por2 contribute to the positive control of Snf1 protein kinase in Saccharomyces cerevisiae.
Eukaryot Cell
2012
21459816
Human leukocyte antigen class I region single-nucleotide polymorphisms are associated with leprosy susceptibility in Vietnam and India.
J Infect Dis
2011
21619464
Genetics of infectious diseases: hidden etiologies and common pathways.
Clin Chem Lab Med
2011
21402756
Joint effects of host genetic background and mycobacterial pathogen on susceptibility to infection.
Infect Immun
2011
19880754
Roles of the Snf1-activating kinases during nitrogen limitation and pseudohyphal differentiation in Saccharomyces cerevisiae.
Eukaryot Cell
2010
21060820
Strain-specific differences in the genetic control of two closely related mycobacteria.
PLoS Pathog
2010
18949820
Detection of endogenous Snf1 and its activation state: application to Saccharomyces and Candida species.
Yeast
2008
17353895
Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy.
Nat Genet
2007
16980405
Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae.
Eukaryot Cell
2006
16801399
An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults.
J Exp Med
2006
16714600
Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.
Infect Immun
2006
15731075
Neutrophil responses to Mycobacterium tuberculosis infection in genetically susceptible and resistant mice.
Infect Immun
2005
14678260
Lung cell responses to M. tuberculosis in genetically susceptible and resistant mice following intratracheal challenge.
Clin Exp Immunol
2004
15291558
Toward fully synthetic carbohydrate-based HIV antigen design: on the critical role of bivalency.
J Am Chem Soc
2004
1 - 50 of 60
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row(s) 1 - 30 of 30
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Co-authored papers
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