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Author Details

Craig D Simpson
The Hospital for Sick Children, University Avenue
2005
18
13
PMIDPaper TitleJournal TitlePublished Year
35181737Numb exon 9 inclusion regulates Integrinβ5 surface expression and promotes breast cancer metastasis.Oncogene2022
33617900SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.J Mol Biol2021
30897078Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.PLoS Biol2019
31350469Global view of the RAF-MEK-ERK module and its immediate downstream effectors.Sci Rep2019
26388441Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.Cell2015
22488300A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance.Apoptosis2012
22957033Suppression of cancer progression by MGAT1 shRNA knockdown.PLoS One2012
22829912Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis.PLoS One2012
20053768Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands.Mol Cancer Ther2010
20348394The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma.Blood2010
19293189Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.Cancer Res2009
18701493Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function.Cancer Res2008
19001437A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death.Mol Cancer Ther2008
18579285Anoikis resistance and tumor metastasis.Cancer Lett2008
17505076Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.J Natl Cancer Inst2007
17804746A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis.Cancer Res2007
158018183-Substituted imidazo[1,2-d][1,2,4]-thiadiazoles: a novel class of factor XIIIa inhibitors.J Med Chem2005
16050682Synthesis of 3-substituted bicyclic imidazo[1,2-d][1,2,4]thiadiazoles and tricyclic benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazoles.J Org Chem2005
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Collaborators

Princess Margaret Cancer Centre
Co-authored papers 11
Princess Margaret Cancer Centre
Co-authored papers 9
Princess Margaret Cancer Centre
Co-authored papers 8
The Scripps Research Institute
Co-authored papers 4
University of Toronto
Co-authored papers 3
University of Perugia
Co-authored papers 3
Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital
Co-authored papers 3
Humboldt-Universitat zu Berlin
Co-authored papers 3
University of Waterloo, University Avenue West
Co-authored papers 2
University of Toronto
Co-authored papers 2
Hospital for Sick Children, University of Toronto
Co-authored papers 2
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University Avenue R988
Co-authored papers 2
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Hospital for Sick Children
Co-authored papers 1
Air Quality Modelling and Integration Research Unit
Co-authored papers 1
University of New Hampshire
Co-authored papers 1
University of Toronto
Co-authored papers 1
Vanderbilt University School of Medicine
Co-authored papers 1
The Ontario Cancer Institute, University Health Network, University of Toronto
Co-authored papers 1
Schroeder Arthritis Institute
Co-authored papers 1
University of Zurich
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University of California los angeles
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College of Life Sciences and Agriculture, University of New Hampshire
Co-authored papers 1
Princess Margaret Hospital, University of Toronto
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Hospital for Sick Children, University of Toronto
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Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1