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Author Details

Christian Schmidl
Leibniz Institute for Immunotherapy
2006
40
29
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36657444Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8<sup>+</sup> T cells.Mol Cell2023
37880183MCT4 blockade increases the efficacy of immune checkpoint blockade.J Immunother Cancer2023
36646694Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species.Nat Commun2023
35606086Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.J Immunother Cancer2022
32217639Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma.Gut2021
33789089Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells.Immunity2021
33758075Cancer-associated cells release citrate to support tumour metastatic progression.Life Sci Alliance2021
32612232Structural cells are key regulators of organ-specific immune responses.Nature2020
31996669Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.Nat Commun2020
31964861Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.Nat Commun2020
31924477Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF.Immunity2020
32098963Author Correction: Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1.Nat Commun2020
32692442Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer.EMBO J2020
32570839Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL.Cells2020
30692684Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL.Nat Chem Biol2019
31427792Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.Nat Genet2019
30836093HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.Gastroenterology2019
30962454Rbpj expression in regulatory T cells is critical for restraining T<sub>H</sub>2 responses.Nat Commun2019
31133746MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.Nat Genet2019
30658577High-throughput ChIPmentation: freely scalable, single day ChIPseq data generation from very low cell-numbers.BMC Genomics2019
29495308The Peripheral and Intratumoral Immune Cell Landscape in Cancer Patients: A Proxy for Tumor Biology and a Tool for Outcome Prediction.Biomedicines2018
30195378Epigenetic mechanisms regulating T-cell responses.J Allergy Clin Immunol2018
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
28099430Pooled CRISPR screening with single-cell transcriptome readout.Nat Methods2017
27072894Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.Biotechnol Bioeng2016
27346425Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks.Nat Commun2016
25450522Genome-wide identification of hypoxia-inducible factor-1 and -2 binding sites in hypoxic human macrophages alternatively activated by IL-10.Biochim Biophys Acta2015
26280331ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors.Nat Methods2015
25704812Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Cell Rep2015
25717144Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells.J Leukoc Biol2015
24671953The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations.Blood2014
24670763An atlas of active enhancers across human cell types and tissues.Nature2014
24670764A promoter-level mammalian expression atlas.Nature2014
24671955Transcription and enhancer profiling in human monocyte subsets.Blood2014
23658224Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1.Nucleic Acids Res2013
22210907Dominant Th2 differentiation of human regulatory T cells upon loss of FOXP3 expression.J Immunol2012
21469109Epigenetic reprogramming of the RORC locus during in vitro expansion is a distinctive feature of human memory but not naïve Treg.Eur J Immunol2011
20201041Isolation of intact genomic DNA from FOXP3-sorted human regulatory T cells for epigenetic analyses.Eur J Immunol2010
19494038Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.Genome Res2009
17022944Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.Biochem Biophys Res Commun2006
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Collaborators

Michael Rehli
University Hospital Regensburg
Co-authored papers 18
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 14
Matthias Edinger
Regensburg University Hospital
Co-authored papers 12
Andr?? F Rendeiro
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 10
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Yoshihide Hayashizaki
Center for Integrative Medical Sciences
Co-authored papers 6
Masayoshi Itoh
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Timo Lassmann
Telethon Kids Institute, University of Western Australia
Co-authored papers 6
Piero Carninci
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
David A Hume
Mater Research Institute-UQ, Translational Research Institute
Co-authored papers 5
Claudia Gebhard
University Hospital Regensburg
Co-authored papers 5
Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Matthias Farlik
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 5
Andreas Lennartsson
Karolinska Institute
Co-authored papers 4
Jun Kawai
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Stefan Kubicek
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Sayaka Nagao-Sato
Ochanomizu University
Co-authored papers 4
Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 3
Nikolaus Fortelny
University of Salzburg
Co-authored papers 3
Jessica Severin
Center for Integrative Medical Sciences
Co-authored papers 3
Magda Babina
Berlin Institute of Health
Co-authored papers 3
Benedikt Brors
German Cancer Research Center (DKFZ)
Co-authored papers 3
Dagmar Glatz
University Hospital Regensburg
Co-authored papers 3
Rainer Spang
University of Regensburg
Co-authored papers 3
Michael Schuster
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Yuri Ishizu
RIKEN Center for Life Science Technologies
Co-authored papers 3
Johanna Raithel
Leibniz Institute for Immunotherapy, c/o University Hospital Regensburg
Co-authored papers 3
Naoto Kondo
Nagoya City University Graduate School of Medical Sciences
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Peter Heutink
German Center for Neurodegenerative Diseases (DZNE).
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Release 1.2