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| 37001527 | Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities. | Cancer Cell | 2023 |
| 35105861 | PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. | Nat Commun | 2022 |
| 35412366 | MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial. | Radiology | 2022 |
| 34737188 | DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition. | Cancer Discovery | 2022 |
| 34964902 | Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant. | Neuro-Oncology | 2022 |
| 34551970 | Repurposing Vandetanib plus Everolimus for the Treatment of <i>ACVR1</i>-Mutant Diffuse Intrinsic Pontine Glioma. | Cancer Discov | 2022 |
| 34644147 | Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas. | Sci Transl Med | 2021 |
| 33859362 | Correction to: Molecular landscape of IDH-mutant primary astrocytoma Grade IV/Glioblastomas. | Mod Pathol | 2021 |
| 33692446 | Molecular landscape of IDH-mutant primary astrocytoma Grade IV/glioblastomas. | Mod Pathol | 2021 |
| 34169282 | Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients. | Neurooncol Adv | 2021 |
| 33900873 | High grade gliomas in young children: The South Thames Neuro-Oncology unit experience and recent advances in molecular biology and targeted therapies. | Pediatric Hematology and Oncology | 2021 |
| 34003511 | Pathogenic ACVR1<sup>R206H</sup> activation by Activin A-induced receptor clustering and autophosphorylation. | EMBO J | 2021 |
| 33300045 | Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma. | Brain | 2021 |
| 33130881 | A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR. | Neuro Oncol | 2021 |
| 34502082 | The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation. | International Journal of Molecular Sciences | 2021 |
| 34433654 | Deconvoluting Mechanisms of Acquired Resistance to RAF Inhibitors in BRAF[V600E]-Mutant Human Glioma. | Clin Cancer Res | 2021 |
| 34545083 | Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B. | Nat Commun | 2021 |
| 34423181 | Recent Advances in ALK2 Inhibitors. | ACS Omega | 2021 |
| 31419298 | WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial. | Neuro Oncol | 2020 |
| 32083745 | Childhood brain tumours as epigenetic diseases. | Neuropathology and Applied Neurobiology | 2020 |
| 31857716 | Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma. | British Journal of Cancer | 2020 |
| 32193787 | Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation. | Acta Neuropathol | 2020 |
| 31786093 | DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study. | Lancet Child Adolesc Health | 2020 |
| 32238360 | Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes. | Cancer Discov | 2020 |
| 31617673 | Challenging the indiscriminate use of temozolomide in pediatric high-grade gliomas: A review of past, current, and emerging therapies. | Pediatric Blood and Cancer | 2020 |
| 32154590 | The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas. | Journal of Pathology | 2020 |
| 32093414 | Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness. | Cells | 2020 |
| 31924736 | Radiological Evaluation of Newly Diagnosed Non-Brainstem Pediatric High-Grade Glioma in the HERBY Phase II Trial. | Clin Cancer Res | 2020 |
| 31701492 | Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2. | Cellular oncology (Dordrecht) | 2020 |
| 32859926 | Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity. | Nat Commun | 2020 |
| 32895736 | Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns. | Acta Neuropathol | 2020 |
| 32942636 | Integration of Multiple Platforms for the Analysis of Multifluorescent Marking Technology Applied to Pediatric GBM and DIPG. | International Journal of Molecular Sciences | 2020 |
| 32832624 | RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma. | Science advances | 2020 |
| 31098401 | ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma. | Commun Biol | 2019 |
| 31779235 | Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric -Mutated Gliomas Recreate the Patient Tumor Complexity. | Cancers | 2019 |
| 31604713 | Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography. | Cancer Research | 2019 |
| 29931585 | Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells. | Investigational New Drugs | 2019 |
| 30446898 | International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma. | J Neurooncol | 2019 |
| 30484110 | Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma. | J Neurooncol | 2019 |
| 31543384 | A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations. | Eur J Cancer | 2019 |
| 31138805 | The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models. | Nat Commun | 2019 |
| 31439867 | PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. | Nat Commun | 2019 |
| 29453317 | Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma. | Molecular Cancer Research | 2018 |
| 30396367 | Transcriptomic and epigenetic profiling of 'diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location. | Acta Neuropathol Commun | 2018 |
| 29967352 | Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells. | Nat Med | 2018 |
| 30102236 | Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group. | Lancet Oncol | 2018 |
| 30085668 | Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept. | Journal of Medicinal Chemistry | 2018 |
| 29763623 | Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial. | Cancer Cell | 2018 |
| 29348602 | The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion. | Scientific Reports | 2018 |
| 29217735 | Immuno-PET in Pontine Glioma: More Than Meets the Eye? | | 2018 |