Author details

Full Name

Amaro Taylor-Weiner

Affiliation

ORCID

Career Start Year

2012

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37162870	AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials.	medRxiv	2023
38070597	Artificial intelligence-powered assessment of pathologic response to neoadjuvant atezolizumab in patients with non-small cell lung cancer: results from the LCMC3 study.		2023
37075704	Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH.	Cell Rep Med	2023
36624313	Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.	Nat Med	2023
35927489	Molecular map of chronic lymphocytic leukemia and its impact on outcome.	Nat Genet	2022
34568833	<i>ZBTB33</i> is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.	Blood Cancer Discov	2021
33531667	Evaluating the molecular diagnostic yield of joint genotyping-based approach for detecting rare germline pathogenic and putative loss-of-function variants.	Genet Med	2021
33570776	A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.	Hepatology	2021
33712588	Human-interpretable image features derived from densely mapped cancer pathology slides predict diverse molecular phenotypes.	Nat Commun	2021
34518531	Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.	Nat Commun	2021
33201204	Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.	JAMA	2020
32015527	Identification of cancer driver genes based on nucleotide context.	Nat Genet	2020
32442065	Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression.	J Clin Oncol	2020
30712845	A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.	Cancer Cell	2019
31675989	Scaling computational genomics to millions of individuals with GPUs.	Genome Biol	2019
31142838	Growth dynamics in naturally progressing chronic lymphocytic leukaemia.	Nature	2019
31526759	Passenger Hotspot Mutations in Cancer.	Cancer Cell	2019
30911113	Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia.	Leukemia	2019
31164371	Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma.	Clin Cancer Res	2019
30676620	Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.	JAMA Oncol	2019
29713087	Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
30150660	Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors.	Nat Genet	2018
29955181	Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29955182	Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29941871	DeTiN: overcoming tumor-in-normal contamination.	Nat Methods	2018
27797976	Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer.	Clin Cancer Res	2017
28664899	Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2017
28658208	Recurrent and functional regulatory mutations in breast cancer.	Nature	2017
28522256	Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.	Gastroenterology	2017
28652578	Rare germline variants in ATM are associated with chronic lymphocytic leukemia.	Leukemia	2017
27905446	Genomic evolution and chemoresistance in germ-cell tumours.	Nature	2016
27348297	The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.	Nat Genet	2016
27199251	Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition.	Nat Commun	2016
27338572	Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2016
27160768	Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth.	Sci Rep	2016
27460824	The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.	Genome Med	2016
26711114	Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia.	Nat Genet	2016
24610117	Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control.	Cerebral Cortex	2015
25415225	Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients.	Oncotarget	2015
25914127	Astrocytic glutamate uptake is slow and does not limit neuronal NMDA receptor activation in the neonatal neocortex.	GLIA	2015
25395418	Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.	Blood	2015
25957691	Prospective derivation of a living organoid biobank of colorectal cancer patients.	Cell	2015
26014096	Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.	Cancer Immunol Res	2015
26466571	Mutations driving CLL and their evolution in progression and relapse.	Nature	2015
26498373	Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.	J Natl Cancer Inst	2015
26457647	The genomic landscape of juvenile myelomonocytic leukemia.	Nat Genet	2015
26410082	Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.	Cancer Discov	2015
26192918	Paired exome analysis of Barrett's esophagus and adenocarcinoma.	Nat Genet	2015
24559677	A local glutamate-glutamine cycle sustains synaptic excitatory transmitter release.	Neuron	2014
25589003	Sporadic hemangioblastomas are characterized by cryptic VHL inactivation.	Acta Neuropathol Commun	2014