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Author Details
Full Name
Darran P O'Connor
Affiliation
UCD Conway Institute, University College Dublin
ORCID
Career Start Year
2001
Papers
68
H Index
32
Expertise
CM4AI Collaborator
Emma Lundberg (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35332319
Author Correction: Antibody-based proteomics: fast-tracking molecular diagnostics in oncology.
Nat Rev Cancer
2022
35711675
Master Transcription Regulators and Transcription Factors Regulate Immune-Associated Differences Between Patients of African and European Ancestry With Colorectal Cancer.
Gastro Hep Adv
2022
33122343
Effects of HER Family-targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast Cancer.
Clin Cancer Res
2021
33523897
Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer.
Sci Adv
2021
34090143
Prognostic value of the 6-gene OncoMasTR test in hormone receptor-positive HER2-negative early-stage breast cancer: Comparative analysis with standard clinicopathological factors.
Eur J Cancer
2021
33955407
An Insight Into the Driver Mutations and Molecular Mechanisms Underlying Mucinous Adenocarcinoma of the Rectum.
Dis Colon Rectum
2021
32555399
Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer.
Sci Rep
2020
33004351
A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer.
Cancer Res
2020
31139326
Correction: BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.
Oncotarget
2019
29961873
Transcriptome Characterization of Matched Primary Breast and Brain Metastatic Tumors to Detect Novel Actionable Targets.
J Natl Cancer Inst
2019
31409615
BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.
Clin Cancer Res
2019
30798618
Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes.
Circ Heart Fail
2019
29069577
Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007.
Cancer Lett
2018
30291241
Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy.
Nat Commun
2018
29644001
BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer.
Oncotarget
2018
29792754
Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.
J Clin Oncol
2018
29567811
Epigenome-wide SRC-1-Mediated Gene Silencing Represses Cellular Differentiation in Advanced Breast Cancer.
Clin Cancer Res
2018
29243812
Dysregulated mitogen-activated protein kinase signalling as an oncogenic basis for clear cell sarcoma of the kidney.
J Pathol
2018
27615392
Mutant p53: a novel target for the treatment of patients with triple-negative breast cancer?
Int J Cancer
2017
32913965
Postmortem Examination of an Aggressive Case of Medullary Thyroid Carcinoma Characterized by Catastrophic Genomic Abnormalities.
JCO Precis Oncol
2017
28487489
Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer.
Oncotarget
2017
28455421
Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.
Cancer Res
2017
28154183
The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways.
J Biol Chem
2017
28213567
Vitamin D receptor as a target for breast cancer therapy.
Endocr Relat Cancer
2017
28554894
Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.
EMBO J
2017
28611295
Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach.
Oncotarget
2017
27796961
Assessment of Significance of Novel Proteins in Breast Cancer Using Tissue Microarray Technology.
Methods Mol Biol
2017
26895288
Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer.
Expert Rev Mol Diagn
2016
27482648
De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I-III breast cancer.
Br J Cancer
2016
27354233
Biosimilars: Extrapolation for oncology.
Crit Rev Oncol Hematol
2016
27377904
RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.
J Natl Cancer Inst
2016
26729235
Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer.
Sci Rep
2016
25626736
Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.
Diabetes
2015
25906750
FKBPL: a marker of good prognosis in breast cancer.
Oncotarget
2015
24649821
microRNAs: a new class of breast cancer biomarkers.
Expert Rev Mol Diagn
2014
25927669
A novel mechanism of regulation of the anti-metastatic miR-31 by EMSY in breast cancer.
Breast Cancer Res
2014
25455730
p53 as a target for the treatment of cancer.
Cancer Treat Rev
2014
25379014
Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture.
Cancer Cell Int
2014
25011585
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.
Breast Cancer Res
2014
22740095
Ghrelin concentrations in maternal and cord blood of type 1 diabetic and non-diabetic pregnancies at term.
Endocrine
2013
24204025
miRNA dysregulation in breast cancer.
Cancer Res
2013
23359479
Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target?
Prostate
2013
22139072
The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ERα, and is an independent prognostic factor in node-negative breast cancer.
Oncogene
2012
22935204
Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer.
Diagn Pathol
2012
23060431
miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in vitro.
Clin Cancer Res
2012
22332848
Maternal and fetal cocaine- and amphetamine-regulated transcript in diabetic and non-diabetic pregnancy.
Gynecol Endocrinol
2012
21281480
Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.
Breast Cancer Res
2011
21999197
Identification of a myometrial molecular profile for dystocic labor.
BMC Pregnancy Childbirth
2011
21982118
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.
Mol Cancer
2011
21677534
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Am J Surg Pathol
2011
1 - 50 of 68
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Lund University
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8
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Uppsala University
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KTH Royal Institute of Technology
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Cancer Center Amsterdam, Vrije Universiteit Amsterdam
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6
Annette T Byrne
Royal College of Surgeons in Ireland (RCSI)
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Diether Lambrechts
Co-authored papers
5
Timo Gaiser
Institut fur Pathologie, Universitatsmedizin Mannheim
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Stephen R Pennington
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Carlos Caldas
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Robert C Millikan
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Aedin C Culhane
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Gillian O'Hurley
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Eugene T Dillon
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