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Author Details

Sean C Proll
Fred Hutchinson Cancer Research Center
2001
68
38
PMIDPaper TitleJournal TitlePublished Year
37207618Changes in Vaginal Bacteria and Inflammatory Mediators From Periconception Through the Early Postpartum Period in a Cohort of Kenyan Women Without HIV.J Infect Dis2023
37480848Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity.Immunity2023
37425928Identification of fallopian tube microbiota and its association with ovarian cancer: a prospective study of intraoperative swab collections from 187 patients.medRxiv2023
37350639Optimizing metaproteomics database construction: lessons from a study of the vaginal microbiome.mSystems2023
36949872Genital Herpes Simplex Virus Type 2 Suppression With Valacyclovir Is Not Associated With Changes in Nugent Score or Absolute Abundance of Key Vaginal Bacteria.Open Forum Infect Dis2023
32379324Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men.J Infect Dis2022
35353163Impact of Topical Interventions on the Vaginal Microbiota and Metabolome in Postmenopausal Women: A Secondary Analysis of a Randomized Clinical Trial.JAMA Netw Open2022
33107562Bacterial Communities Associated With Abnormal Nugent Score in Postmenopausal Versus Premenopausal Women.J Infect Dis2021
33675793Association between postmenopausal vulvovaginal discomfort, vaginal microbiota, and mucosal inflammation.Am J Obstet Gynecol2021
32265316Complementing 16S rRNA Gene Amplicon Sequencing with Total Bacterial Load To Infer Absolute Species Concentrations in the Vaginal Microbiome.mSystems2020
25589554Next-generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with vesicular stomatitis virus expressing Zaire Ebola virus glycoprotein (VSVοG/EBOVgp).Clin Vaccine Immunol2015
24850744Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy.J Virol2014
25118237Influenza virus A/Anhui/1/2013 (H7N9) replicates efficiently in the upper and lower respiratory tracts of cynomolgus macaques.mBio2014
24846384Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.mBio2014
23544010A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes.PLoS Pathog2013
23919993Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury.mBio2013
23455712Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses.Nat Med2013
22331615Proteome and computational analyses reveal new insights into the mechanisms of hepatitis C virus-mediated liver disease posttransplantation.Hepatology2012
22532686Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses.J Virol2012
22542004Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.Virology2012
22608059Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.Virology2012
22278598Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients.Hepatology2012
21084481Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.J Virol2011
22086488Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection.mBio2011
21865398Host regulatory network response to infection with highly pathogenic H5N1 avian influenza virus.J Virol2011
21593271The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.J Gen Virol2011
21285433A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.mBio2011
20062526Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics.PLoS Pathog2010
20949022Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice.PLoS Pathog2010
20926563Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection.J Virol2010
20978541Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling.mBio2010
20504916Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.J Virol2010
19939913The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling.J Virol2010
19214219Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization.PLoS Pathog2009
19692471A single-amino-acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T-cell activation in mice.J Virol2009
19671175Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers.BMC Genomics2009
19706713The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways.J Virol2009
19798428Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.PLoS Pathog2009
19420084Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection.J Virol2009
19461876P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.PLoS Pathog2009
19109391Host responses to wild-type and attenuated herpes simplex virus infection in the absence of Stat1.J Virol2009
19297498Impaired cholesterol biosynthesis in a neuronal cell line persistently infected with measles virus.J Virol2009
19218453Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus.Proc Natl Acad Sci U S A2009
19214220Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection.PLoS Pathog2009
18809758Down-regulation of hepcidin in porphyria cutanea tarda.Blood2008
17244361High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations.BMC Genomics2007
18066032Systems biology and the host response to viral infection.Nat Biotechnol2007
17654742Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction.Hepatology2007
17715226Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus.J Virol2007
17166899The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism.J Virol2007
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Collaborators

University of Washington
Co-authored papers 52
University of Washington
Co-authored papers 12
Centers for Disease Control and Prevention.
Co-authored papers 10
Fred Hutchinson Cancer Center
Co-authored papers 9
Co-authored papers 8
Pacific Northwest National Laboratory
Co-authored papers 7
University of Washington
Co-authored papers 6
Influenza Research Institute, University of Wisconsin
Co-authored papers 6
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Co-authored papers 6
Co-authored papers 5
Clinical Research Division, Fred Hutchinson Cancer Research Center
Co-authored papers 5
Pacific Northwest National Laboratory
Co-authored papers 5
University of North Carolina
Co-authored papers 5
Pacific Northwest National Laboratory
Co-authored papers 5
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 5
University of Chicago, Gwen Knapp Center for Lupus Research.
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
University of North Carolina at Chapel Hill
Co-authored papers 4
University of Washington, USA Washington National Primate Research Center
Co-authored papers 4
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 3
Center for Pathogen Research, University of Maryland School of Medicine
Co-authored papers 3
Pacific Northwest National Laboratory
Co-authored papers 3
Harbin Veterinary Research Institute
Co-authored papers 3
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 3
Co-authored papers 3
University of North Carolina.
Co-authored papers 3
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 3
Pacific Northwest National Laboratory
Co-authored papers 3
Pacific Northwest National Laboratory
Co-authored papers 3