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Author Details

Dino Moras
Laboratory IGBMC (Institute of Genetics and of Molecular and Cellular Biology)
1973
343
91
PMIDPaper TitleJournal TitlePublished Year
37404310Structural insights into the HNF4 biology.Front Endocrinol (Lausanne)2023
37503845Asymmetric dimerization in a transcription factor superfamily is promoted by allosteric interactions with DNA.Nucleic Acids Res2023
36199108A novel nuclear receptor subfamily enlightens the origin of heterodimerization.BMC Biol2022
33441854Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions.Sci Rep2021
33882063A structural signature motif enlightens the origin and diversification of nuclear receptors.PLoS Genet2021
33746550Nonsteroidal ecdysone receptor agonists use a water channel for binding to the ecdysone receptor complex EcR/USP.J Pestic Sci2021
31965182Correlation between equi-partition of aminoacyl-tRNA synthetases and amino-acid biosynthesis pathways.Nucleic Acids Res2020
30713160A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor retinoic X receptor α.Acta Crystallogr F Struct Biol Commun2019
28676789Importance of the Sequence-Directed DNA Shape for Specific Binding Site Recognition by the Estrogen-Related Receptor.Front Endocrinol (Lausanne)2017
28435861Origin of an ancient hormone/receptor couple revealed by resurrection of an ancestral estrogen.Sci Adv2017
27226617Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases.J Biol Chem2016
25645674Structural basis of natural promoter recognition by the retinoid X nuclear receptor.Sci Rep2015
25899756Structure-function relationships in nuclear receptors: the facts.Trends Biochem Sci2015
25620699A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects.Cell Rep2015
24962879Architecture of DNA Bound RAR heterodimers.Subcell Biochem2014
24942373The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning.Nat Commun2014
23147676Functional insights into the core-TFIIH from a comparative survey.Genomics2013
23874451The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism.PLoS One2013
24000896Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules.Biochemistry2013
23593299Structural and functional role of INI1 and LEDGF in the HIV-1 preintegration complex.PLoS One2013
23499886Allosteric controls of nuclear receptor function in the regulation of transcription.J Mol Biol2013
23332751Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination.Cell2013
21888944Structural analysis of nuclear receptors: from isolated domains to integral proteins.Mol Cell Endocrinol2012
23319938Solution Structures of PPARγ2/RXRα Complexes.PPAR Res2012
22957834Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin D nuclear receptor.J Med Chem2012
22696218TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.J Biol Chem2012
22921063Synthetically accessible non-secosteroidal hybrid molecules combining vitamin D receptor agonism and histone deacetylase inhibition.Chem Biol2012
22490469Expression of functional full-length hSRC-1 in eukaryotic cells using modified vaccinia virus Ankara and baculovirus.Anal Biochem2012
22661711Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.J Biol Chem2012
22213324Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile.Anticancer Res2012
22355136Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors.Proc Natl Acad Sci U S A2012
22033674In vivo topoisomerase I inhibition attenuates the expression of hypoxia-inducible factor 1α target genes and decreases tumor angiogenesis.Mol Med2012
22162241Design, synthesis, evaluation, and structure of vitamin D analogues with furan side chains.Chemistry2012
22179700Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA.EMBO J2012
20813758M-ORBIS: mapping of molecular binding sites and surfaces.Nucleic Acids Res2011
22180837Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.Medchemcomm2011
21520419Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin⿿D3 with substituents at C18.ChemMedChem2011
21571073Structural insights into transcription complexes.J Struct Biol2011
21322567Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors.J Med Chem2011
214838241α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptor.PLoS One2011
21478865Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.Nat Struct Mol Biol2011
20070104Structure-function relationships and crystal structures of the vitamin D receptor bound 2 alpha-methyl-(20S,23S)- and 2 alpha-methyl-(20S,23R)-epoxymethano-1 alpha,25-dihydroxyvitamin D3.J Med Chem2010
21080938Insights into metazoan evolution from Alvinella pompejana cDNAs.BMC Genomics2010
21152046The "Phantom Effect" of the Rexinoid LG100754: structural and functional insights.PLoS One2010
21149735Proofreading in translation: dynamics of the double-sieve model.Proc Natl Acad Sci U S A2010
20534350Quantitative cell-based reporter gene assays using droplet-based microfluidics.Chem Biol2010
20496064Dynamic correlation networks in human peroxisome proliferator-activated receptor-γ nuclear receptor protein.Eur Biophys J2010
20624369Analysis of recombinant phosphoprotein complexes with complementary mass spectrometry approaches.Anal Biochem2010
20346396Design and synthesis of active vitamin D analogs.J Steroid Biochem Mol Biol2010
20403435Crystal structure of hereditary vitamin D-resistant rickets--associated mutant H305Q of vitamin D nuclear receptor bound to its natural ligand.J Steroid Biochem Mol Biol2010
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Collaborators

Institut de Genetique et de Biologie Moleculaire et Cellulaire
Co-authored papers 12
Okinawa Institute of Science and Technology
Co-authored papers 7
King's College London BHF Centre for Research Excellence
Co-authored papers 5
Shinshu University School of Medicine
Co-authored papers 4
Purdue University
Co-authored papers 4
Universite de Lyon, Universite Lyon 1, CNRS UMR 5242
Co-authored papers 3
Universita` degli Studi di Milano
Co-authored papers 3
University of Southern California
Co-authored papers 3
Weizmann Institute of Science
Co-authored papers 3
Utrecht University
Co-authored papers 2
INRAE-Institut National de Recherche pour l'Agriculture
Co-authored papers 2
Harvard University
Co-authored papers 2
Co-authored papers 1
University of Lausanne
Co-authored papers 1
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences
Co-authored papers 1
Institut Francois Jacob, CNRS, Universite Paris-Saclay
Co-authored papers 1
University of Virginia School of Medicine
Co-authored papers 1
Global Phasing Ltd
Co-authored papers 1
Universita di Torino
Co-authored papers 1
Institut Systematique, CNRS
Co-authored papers 1
Co-authored papers 1
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 1
Weizmann Institute of Science
Co-authored papers 1
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Weizmann Institute of Science
Co-authored papers 1
Universite Paris-Saclay, CNRS, Institute for Integrative Biology of the Cell (I2BC)
Co-authored papers 1
University of California riverside
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Universita degli Studi di Milano
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Max-Delbruck-Center for Molecular Medicine in the Helmholtz Association (MDC)
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INSERM, Universite de Strasbourg
Co-authored papers 1