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Author Details

Sang-Won Min
Gladstone Institutes
2000
21
19
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35063084Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.Cell2022
34981791Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.J Clin Invest2022
33727605Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity.Sci Rep2021
29540553SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.J Neurosci2018
28972160An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.J Biol Chem2017
29124108An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from <i>GRN</i> gene mutations.Alzheimers Dement (N Y)2017
27041503Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron2016
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
25374362The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.Neuron2014
25261995Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.Nat Med2014
24093018Sirtuins in neurodegenerative diseases: an update on potential mechanisms.Front Aging Neurosci2013
24133272Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability.J Neurosci2013
23041626Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.J Clin Invest2012
20869593Acetylation of tau inhibits its degradation and contributes to tauopathy.Neuron2010
18703708Conformational switch of syntaxin-1 controls synaptic vesicle fusion.Science2008
17360437E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains.Proc Natl Acad Sci U S A2007
12506202Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins.Proc Natl Acad Sci U S A2003
11879635Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif.Dev Cell2002
12110575How Tlg2p/syntaxin 16 'snares' Vps45.EMBO J2002
12107281Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69.Proc Natl Acad Sci U S A2002
10880343Tissue-specificity, functional characterization and subcellular localization of a rat ubiquitin-specific processing protease, UBP109, whose mRNA expression is developmentally regulated.Biochem J2000
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Collaborators

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Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 9
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Gladstone Institutes
Co-authored papers 6
Peter Dongmin Sohn
Gladstone Institutes
Co-authored papers 5
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University of Texas Southwestern Medical Center
Co-authored papers 4
Yaqiao Li
Harvard Medical School
Co-authored papers 4
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Co-authored papers 4
Nevan J Krogan (CM4AI)
University of California San Francisco
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Jiangsu Simcere Pharmaceutical Co. Ltd.
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National Institute of Neurological, National Institutes of Health (NIH)
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Mehrdad Shamloo
Stanford University School of Medicine
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William W Seeley
UCSF Weill Institute for Neurosciences, University of California san francisco
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Birgit Schilling
Buck Institute for Research on Aging
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Xu Chen
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Jeffrey R Johnson
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Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
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Lauren Sweetland-Martin
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Li Gan
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Chandrani Mukherjee
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Shiaoching Gong
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Anna Karydas
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