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Author Details

Evan F Lind
Oregon Health & Science University
1999
34
23
PMIDPaper TitleJournal TitlePublished Year
36681742BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8<sup>+</sup> T cells.Leukemia2023
37781631Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency.bioRxiv2023
37199721Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases.Clin Cancer Res2023
35868306Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.Cancer Cell2022
32203139Immunomodulatory effects of pevonedistat, a NEDD8-activating enzyme inhibitor, in chronic lymphocytic leukemia-derived T cells.Leukemia2021
32898857Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph+ ALL.Blood2021
32513686Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.Proc Natl Acad Sci U S A2020
30651561Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.Nat Commun2019
31648326Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway.Blood Adv2019
30425048CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells.Blood2019
29175391Integrated functional and mass spectrometry-based flow cytometric phenotyping to describe the immune microenvironment in acute myeloid leukemia.J Immunol Methods2018
30067970Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8<sup>+</sup> T Cell Expansion and Differentiation.Cell Rep2018
29951373Targeting the Immune Microenvironment in Acute Myeloid Leukemia: A Focus on T Cell Immunity.Front Oncol2018
27424808Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.Cancer Cell2016
25882048Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.Cell Death Differ2015
26447227miR-155 Upregulation in Dendritic Cells Is Sufficient To Break Tolerance In Vivo by Negatively Regulating SHIP1.J Immunol2015
24571026Mir-155, a central modulator of T-cell responses.Eur J Immunol2014
23275599Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges.J Immunol2013
21765460The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk.Oncogene2012
22763442IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.Nature2012
22529912Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells.PLoS One2012
20133759HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.Proc Natl Acad Sci U S A2010
19995955Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo.J Exp Med2009
18566401Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens.J Immunol2008
17360936The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation.Blood2007
17374402Strategies for selective priming of memory B cells.Immunol Lett2007
16921386Mast cells are essential intermediaries in regulatory T-cell tolerance.Nature2006
17114443Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.J Immunol2006
15032580CD40/CD154 interactions at the interface of tolerance and immunity.Annu Rev Immunol2004
12049718Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo.Immunity2002
11967542The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells.Nat Immunol2002
11457887Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development.J Exp Med2001
10421778A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+)CD8(+) thymocytes.Int Immunol1999
10228014Bcl-2-induced changes in E2F regulatory complexes reveal the potential for integrated cell cycle and cell death functions.J Immunol1999
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Collaborators

Oregon Health & Science University
Co-authored papers 8
Oregon Health & Science University, University of California Berkeley
Co-authored papers 6
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Oregon Health & Science University
Co-authored papers 5
Oregon Health & Science University School of Medicine
Co-authored papers 5
Seattle Children's Hospital, University of Washington
Co-authored papers 5
Oregon Health & Science University
Co-authored papers 4
Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network
Co-authored papers 4
Oregon Health and Science University
Co-authored papers 3
St Jude Children's Research Hospital.
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Oregon Health and Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
University of Texas Southwestern Medical Center
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health & Science University, Knight Cancer Institute
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2