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Author Details
Full Name
Jason A Sprowl
Affiliation
School of Pharmacy and Pharmaceutical Sciences, University at Buffalo
ORCID
Career Start Year
2007
Papers
30
H Index
20
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36352830
Comparison of P-glycoprotein function in peripheral blood mononuclear cells ex vivo in stable Black and White male and female kidney transplant recipients.
Clin Transl Sci
2023
35390174
Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.
Clin Pharmacol Ther
2022
35383108
Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake.
Mol Pharmacol
2022
35546260
Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4.
Clin Pharmacol Ther
2022
34330821
Current Understanding of Membrane Transporters as Regulators or Targets for Cisplatin-Induced Hearing Loss.
Mol Pharmacol
2021
33664059
Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.
Clin Cancer Res
2021
32484793
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
J Clin Invest
2020
29337310
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.
J Clin Invest
2018
30028006
Strategies to Reduce Solute Carrier-Mediated Toxicity.
Clin Pharmacol Ther
2018
29756222
Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium.
Clin Pharmacol Ther
2018
28689374
Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.
Clin Transl Sci
2017
26979622
A phosphotyrosine switch regulates organic cation transporters.
Nat Commun
2016
25823781
Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.
Pharmacogenomics
2015
25848011
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions.
Proc Natl Acad Sci U S A
2015
24378324
Uptake carriers and oncology drug safety.
Drug Metab Dispos
2014
24916697
Cisplatin-induced renal injury is independently mediated by OCT2 and p53.
Clin Cancer Res
2014
22986709
Polymorphic transporters and platinum pharmacodynamics.
Drug Metab Pharmacokinet
2013
23863876
Conjunctive therapy of cisplatin with the OCT2 inhibitor cimetidine: influence on antitumor efficacy and systemic clearance.
Clin Pharmacol Ther
2013
23960178
Can erlotinib ameliorate cisplatin-induced toxicities?
J Clin Oncol
2013
23640974
CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.
Clin Cancer Res
2013
23776246
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2.
Proc Natl Acad Sci U S A
2013
23757163
Modulation of OATP1B-type transporter function alters cellular uptake and disposition of platinum chemotherapeutics.
Mol Cancer Ther
2013
22223530
Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.
Clin Cancer Res
2012
22938713
Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization.
BMC Cancer
2012
23085872
Drug trafficking: recent advances in therapeutics and disease.
Clin Pharmacol Ther
2012
22534871
Associations between ABCC2 polymorphisms and cisplatin disposition and efficacy.
Clin Pharmacol Ther
2012
22459901
Contribution of tumoral and host solute carriers to clinical drug response.
Drug Resist Updat
2012
22225778
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.
Breast Cancer Res
2012
20125118
The temporal relationship between ABCB1 promoter hypomethylation, ABCB1 expression and acquisition of drug resistance.
Pharmacogenomics J
2010
17512223
Changes in expression of cell wall turnover genes accompany inhibition of chromosome segregation by bovine protein kinase C alpha expression in Saccharomyces cerevisiae.
Cell Biol Int
2007
1 - 30 of 30
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