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Author Details
Full Name
Nicholas P Restifo
Affiliation
National Cancer Institute, National Institutes of Health (NIH)
ORCID
Career Start Year
1985
Papers
349
H Index
133
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37377887
Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.
Cancer Res Commun
2023
37159663
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.
Cell Rep Methods
2023
37377887
Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.
Cancer Res Commun
2023
37159663
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.
Cell Rep Methods
2023
34710751
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity.
Curr Opin Immunol
2022
36007524
Internal checkpoint regulates TÂ cell neoantigen reactivity and susceptibility to PD1 blockade.
Med
2022
36002586
Fine-tuning T cell function through engineered orthogonal chimeric cytokine receptors.
Cell Res
2022
35926468
Cancer genes disfavoring TÂ cell immunity identified via integrated systems approach.
Cell Rep
2022
34710751
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity.
Curr Opin Immunol
2022
36002586
Fine-tuning T cell function through engineered orthogonal chimeric cytokine receptors.
Cell Res
2022
35926468
Cancer genes disfavoring TÂ cell immunity identified via integrated systems approach.
Cell Rep
2022
36007524
Internal checkpoint regulates TÂ cell neoantigen reactivity and susceptibility to PD1 blockade.
Med
2022
33382402
STING agonist promotes CAR T cell trafficking and persistence in breast cancer.
J Exp Med
2021
33893050
Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion.
Cytotherapy
2021
33271120
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Immunity
2021
33382402
STING agonist promotes CAR T cell trafficking and persistence in breast cancer.
J Exp Med
2021
34526724
An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.
Nature
2021
33893050
Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion.
Cytotherapy
2021
34526724
An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.
Nature
2021
33271120
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Immunity
2021
32231230
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.
Sci Rep
2020
31959727
Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.
J Immunother Cancer
2020
32231230
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.
Sci Rep
2020
31996390
Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Clin Cancer Res
2020
32284588
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Nat Med
2020
32516591
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.
Cancer Cell
2020
33234163
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.
Stem Cell Res Ther
2020
33125888
Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy.
Cell
2020
33334372
Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.
Stem Cell Res Ther
2020
31996390
Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Clin Cancer Res
2020
31959727
Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.
J Immunother Cancer
2020
33334372
Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.
Stem Cell Res Ther
2020
33125888
Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy.
Cell
2020
33234163
Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.
Stem Cell Res Ther
2020
32284588
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Nat Med
2020
32516591
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.
Cancer Cell
2020
30694219
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.
J Clin Invest
2019
31591590
Developing neoantigen-targeted T cell-based treatments for solid tumors.
Nat Med
2019
31844254
Identifying the source of tumour-infiltrating T cells.
Nature
2019
31628526
Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.
Cancer Immunol Immunother
2019
31710026
Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells.
J Vis Exp
2019
31092734
An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.
JCI Insight
2019
30923193
T cell stemness and dysfunction in tumors are triggered by a common mechanism.
Science
2019
30694219
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.
J Clin Invest
2019
31449236
A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants.
J Vis Exp
2019
31405895
Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells.
J Exp Med
2019
30778251
The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.
Nat Immunol
2019
30714987
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.
J Clin Invest
2019
30882547
Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma.
J Immunother
2019
30712990
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Mol Cell
2019
1 - 50 of 698
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