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Author Details

Sara J C Gosline
Pacific Northwest National Laboratory (PNNL)
2006
31
16
PMIDPaper TitleJournal TitlePublished Year
36778419CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.bioRxiv2023
38000020CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.Sci Adv2023
36778419CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.bioRxiv2023
36944655The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes.Sci Data2023
37246765Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology.Neuro Oncol2023
38000020CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.Sci Adv2023
37246765Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology.Neuro Oncol2023
36944655The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes.Sci Data2023
35896960Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML.Clin Proteomics2022
35896960Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML.Clin Proteomics2022
34171263The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance.Cancer Cell2021
33591953Chromosome 8 gain is associated with high-grade transformation in MPNST.JCI Insight2021
33703901leapR: An R Package for Multiomic Pathway Analysis.J Proteome Res2021
33585982Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).Acta Neuropathol2021
34171263The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance.Cancer Cell2021
33681983Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data.Brief Bioinform2021
33681983Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data.Brief Bioinform2021
33591953Chromosome 8 gain is associated with high-grade transformation in MPNST.JCI Insight2021
33703901leapR: An R Package for Multiomic Pathway Analysis.J Proteome Res2021
33585982Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).Acta Neuropathol2021
32561749A clinically and genomically annotated nerve sheath tumor biospecimen repository.Sci Data2020
32098059Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1.Genes (Basel)2020
32561749A clinically and genomically annotated nerve sheath tumor biospecimen repository.Sci Data2020
32098059Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1.Genes (Basel)2020
30348677Spatiotemporal Loss of <i>NF1</i> in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.Cancer Discov2019
31836719Engaging a community to enable disease-centric data sharing with the NF Data Portal.Sci Data2019
30348677Spatiotemporal Loss of <i>NF1</i> in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.Cancer Discov2019
31107888The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.PLoS One2019
31836719Engaging a community to enable disease-centric data sharing with the NF Data Portal.Sci Data2019
31107888The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.PLoS One2019
29695767Cutaneous neurofibromas in the genomics era: current understanding and open questions.Br J Cancer2018
29893754Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.Sci Data2018
30128806Probing the chemical-biological relationship space with the Drug Target Explorer.J Cheminform2018
29695767Cutaneous neurofibromas in the genomics era: current understanding and open questions.Br J Cancer2018
30128806Probing the chemical-biological relationship space with the Drug Target Explorer.J Cheminform2018
29893754Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.Sci Data2018
29023490Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens.PLoS One2017
28398289A high-throughput molecular data resource for cutaneous neurofibromas.Sci Data2017
29023490Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens.PLoS One2017
28398289A high-throughput molecular data resource for cutaneous neurofibromas.Sci Data2017
26748710Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements.Cell Rep2016
26748710Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements.Cell Rep2016
27096930Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package.PLoS Comput Biol2016
27315426Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia.Integr Biol (Camb)2016
27864348Systems Approaches to Cancer Biology.Cancer Res2016
27864348Systems Approaches to Cancer Biology.Cancer Res2016
27315426Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia.Integr Biol (Camb)2016
27096930Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package.PLoS Comput Biol2016
25414365SAMNetWeb: identifying condition-specific networks linking signaling and transcription.Bioinformatics2015
25414365SAMNetWeb: identifying condition-specific networks linking signaling and transcription.Bioinformatics2015
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Collaborators

Justin Guinney
University of Washington
Co-authored papers 11
Ernest Fraenkel
Co-authored papers 7
Robert J Allaway
Geisel School of Medicine, Dartmouth College
Co-authored papers 6
Christine A Pratilas
Johns Hopkins University School of Medicine
Co-authored papers 6
Angela C Hirbe
Washington University School of Medicine and Siteman Cancer Center
Co-authored papers 5
Kai Pollard
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Co-authored papers 5
Salvatore La Rosa
university of massachusetts amherst Chan Medical School
Co-authored papers 4
Xiaochun Zhang
Siteman Cancer Center, Washington University School of Medicine
Co-authored papers 4
Jaishri O Blakeley
Johns Hopkins University
Co-authored papers 4
Jiawan Wang
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Co-authored papers 3
Annette Bakker
Children's Tumor Foundation
Co-authored papers 3
Xindi Guo
Sage Bionetworks, University of Washington
Co-authored papers 3
David A Largaespada
University of Minnesota
Co-authored papers 3
Fausto J Rodriguez
University of California Los Angeles
Co-authored papers 3
Jason E McDermott
Pacific Northwest National Laboratory
Co-authored papers 3
Jineta Banerjee
UW Medicine Diabetes Institute, University of Washington
Co-authored papers 3
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 2
Jeffrey W Tyner
Oregon Health & Science University School of Medicine
Co-authored papers 2
Karl K Weitz
Pacific Northwest National Laboratory
Co-authored papers 2
Pamela Knight
Children's Tumor Foundation
Co-authored papers 2
Joshua R Hansen
Pacific Northwest National Laboratory
Co-authored papers 2
Paul D Piehowski
Pacific Northwest National Laboratory
Co-authored papers 2
Jamie Moon
Saint John's Cancer Institute (SJCI)
Co-authored papers 2
Sharad K Verma
Johns Hopkins University
Co-authored papers 2
Shao-Shan Carol Huang
Salk Institute for Biological Studies
Co-authored papers 2
Sunil K Joshi
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Elie Traer
Oregon Health & Science University
Co-authored papers 2
Cristina E Tognon
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Karin D Rodland
Oregon Health and Science University
Co-authored papers 2
Brian J Druker
Oregon Health & Science University
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Release 1.2