Author details

Full Name

Frances Burden

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36806949	A shared 'vulnerability code' underpins varying sources of DNA damage throughout paternal germline transmission in mouse.		2023
35279219	Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.	Clin Epigenetics	2022
35546158	3D chromatin remodelling in the germ line modulates genome evolutionary plasticity.	Nature Communications	2022
32703790	Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas.	Haematologica	2021
33587817	Transcriptional characterization of human megakaryocyte polyploidization and lineage commitment.	J Thromb Haemost	2021
33863903	Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.	Nat Commun	2021
32693407	Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome.	Blood	2020
31217188	Germline mutations in the transcription factor IKZF5 cause thrombocytopenia.	Blood	2019
30467204	Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia.	Haematologica	2019
28870212	Chromosome contacts in activated T cells identify autoimmune disease candidate genes.	Genome Biol	2017
28703137	Platelet function is modified by common sequence variation in megakaryocyte super enhancers.	Nat Commun	2017
27863249	Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.	Cell	2016
27898055	Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.	Nat Commun	2016
27851971	Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems.	Cell Rep	2016
27863251	Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.	Cell	2016
24496437	Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision.	Molecular Therapy - Nucleic Acids	2014
25258084	Transcriptional diversity during lineage commitment of human blood progenitors.	Science	2014
25258085	Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.	Science	2014
22203606	In vitro characterization of the activity of PF-05095808, a novel biological agent for hepatitis C virus therapy.	Antimicrobial Agents and Chemotherapy	2012
22476912	Therapy with TLR7 agonists induces lymphopenia: correlating pharmacology to mechanism in a mouse model.	Journal of Clinical Immunology	2012
21709085	Knockdown of USP18 increases Î± 2a interferon signaling and induction of interferon-stimulating genes but does not increase antiviral activity in Huh7 cells.	Antimicrobial Agents and Chemotherapy	2011
20514817	The effects of gender violence/ harassment prevention programming in middle schools: a randomized experimental evaluation.	Violence and Victims	2010
17096195	Project ALERT with outside leaders: what leader characteristics are important for success?	Prevention Science	2007