Author details

Full Name

Robert J Coffey

Affiliation

ORCID

Career Start Year

1948

Papers

472

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36914899	Comprehensive isolation of extracellular vesicles and nanoparticles.		2023
37843535	Evidence for lung barrier regeneration by differentiation prior to binucleated and stem cell division.	J Cell Biol	2023
37840781	Emerging connections between GPI-anchored proteins and their extracellular carriers in colorectal cancer.		2023
37986961	Transcriptomic Profiling Reveals Claudin 18.2 as a Diagnostic Biomarker of MÃ©nÃ©trier's Disease and the Role of Hedgehog Signaling in Pathogenesis.		2023
37781604	GammaGateR: semi-automated marker gating for single-cell multiplexed imaging.	bioRxiv	2023
37091910	Development of Pluoronic nanoparticles of fluorocoxib A for endoscopic fluorescence imaging of colonic adenomas.		2023
36961472	Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report.		2023
37444556	Systematic Assessment of Small RNA Profiling in Human Extracellular Vesicles.		2023
36993731	Golgi organization is a determinant of stem cell function in the small intestine.	bioRxiv	2023
36737375	Extracellular vesicles and nanoparticles: emerging complexities.		2023
37357017	Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK-dependent colorectal cancer.		2023
37228754	exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers.	Cell Genom	2023
37541751	[<sup>18</sup>F]-fluoroethyl-L-tyrosine (FET) in glioblastoma (FIG) TROG 18.06 study: protocol for a prospective, multicentre PET/CT trial.	BMJ Open	2023
36915679	Bulk and mosaic deletions of <i>Egfr</i> reveal regionally defined gliogenesis in the developing mouse forebrain.	iScience	2023
35084791	MIRIAM: A machine and deep learning single-cell segmentation and quantification pipeline for multi-dimensional tissue images.	Cytometry A	2022
36311879	Are Supermeres a Distinct Nanoparticle?		2022
35958027	Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.	iScience	2022
35678528	Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice.	Cancer Discov	2022
35724732	Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer.	Gastroenterology	2022
35600339	Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.	Front Oncol	2022
36496485	Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins.		2022
33931465	First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-C]-Glutamine in Patients with Metastatic Colorectal Cancer.		2022
35279145	Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates mA-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression.	Molecular Cancer	2022
34983062	Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images.	Bioinformatics	2022
35289315	A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer.	Journal of Clinical Investigation	2022
34824477	MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging.	Nat Methods	2022
35104827	Commentary on the Continued Investigational Status of DBS for Psychiatric Indications.	Stereotactic and Functional Neurosurgery	2022
35284114	Significance of a calcium-binding protein S100A14 expression in colon cancer progression.	Journal of Gastrointestinal Oncology	2022
34887515	Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.	Nat Cell Biol	2021
33468584	Murine Intrarectal Instillation of Purified Recombinant Toxins Enables Mechanistic Studies of Pathogenesis.	Infection and Immunity	2021
34037774	Cell surface integrin Î±5Ã¿1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3.	Integr Biol (Camb)	2021
33989815	Cell-Autonomous Role of EGFR in Spontaneous Duodenal Tumors in LRIG1 Null Mice.	Cellular and Molecular Gastroenterology and Hepatology	2021
33022277	Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein.	Gastroenterology	2021
34406412	Induction of apically mistrafficked epiregulin disrupts epithelial polarity via aberrant EGFR signaling.	Journal of Cell Science	2021
34910928	Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.	Cell	2021
32828819	Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.	Gastroenterology	2020
32193312	Stanley Cohen (1922-2020).	Science	2020
31866246	Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor.	Gastroenterology	2020
31858797	Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.	Journal of Medicinal Chemistry	2020
32652471	Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer.	Translational Oncology	2020
32978434	Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells.	Scientific Reports	2020
32641995	KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling.	Theranostics	2020
32973205	Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms.	NPJ Biofilms Microbiomes	2020
32686657	Elevating EGFR-MAPK program by a nonconventional Cdc42 enhances intestinal epithelial survival and regeneration.	JCI insight	2020
33062167	Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib.	ACS Medicinal Chemistry Letters	2020
32944951	A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.	J Pathol	2020
31373345	scRNABatchQC: multi-samples quality control for single cell RNA-seq data.	Bioinformatics	2019
31809739	Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress.		2019
31754405	miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44.	Theranostics	2019
30585163	Active Kras Expression inÂ Gastric Isthmal Progenitor Cells Induces Foveolar Hyperplasia but Not Metaplasia.	Cellular and Molecular Gastroenterology and Hepatology	2019