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Author Details

Rachel Karchin
Johns Hopkins University
1998
127
55
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36702947Persistent mutation burden drives sustained anti-tumor immune responses.Nat Med2023
37744342Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer.Front Immunol2023
37829001Deep neural networks predict class I major histocompatibility complex epitope presentation and transfer learn neoepitope immunogenicity.Nat Mach Intell2023
36653470Clustering by antigen-presenting genes reveals immune landscapes and predicts response to checkpoint immunotherapy.Sci Rep2023
36702947Persistent mutation burden drives sustained anti-tumor immune responses.Nat Med2023
37121856Corrigendum to "HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade": [Annals of Oncology volume 33 (2022) 728-738].Ann Oncol2023
37744342Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer.Front Immunol2023
37829001Deep neural networks predict class I major histocompatibility complex epitope presentation and transfer learn neoepitope immunogenicity.Nat Mach Intell2023
37121856Corrigendum to "HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade": [Annals of Oncology volume 33 (2022) 728-738].Ann Oncol2023
36653470Clustering by antigen-presenting genes reveals immune landscapes and predicts response to checkpoint immunotherapy.Sci Rep2023
35339648HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade.Ann Oncol2022
35642899Estimation of cancer cell fractions and clone trees from multi-region sequencing of tumors.Bioinformatics2022
35992816Sex-specific differences in immunogenomic features of response to immune checkpoint blockade.Front Oncol2022
36053203Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma.J Natl Cancer Inst2022
36377311Experimental and <i>In Silico</i> Analysis of TEM β-Lactamase Adaptive Evolution.ACS Infect Dis2022
35533264Pan-Cancer HLA Gene-Mediated Tumor Immunogenicity and Immune Evasion.Mol Cancer Res2022
35339648HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade.Ann Oncol2022
35642899Estimation of cancer cell fractions and clone trees from multi-region sequencing of tumors.Bioinformatics2022
35533264Pan-Cancer HLA Gene-Mediated Tumor Immunogenicity and Immune Evasion.Mol Cancer Res2022
35992816Sex-specific differences in immunogenomic features of response to immune checkpoint blockade.Front Oncol2022
36053203Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma.J Natl Cancer Inst2022
36377311Experimental and <i>In Silico</i> Analysis of TEM β-Lactamase Adaptive Evolution.ACS Infect Dis2022
33323400The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas.Clin Cancer Res2021
33028669Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic <i>KLF4</i> mutations predominantly in low-grade regions.Gut2021
33323400The Genetic Evolution of Treatment-Resistant Cutaneous, Acral, and Uveal Melanomas.Clin Cancer Res2021
34750557Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial.Nat Med2021
34750557Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial.Nat Med2021
33028669Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic <i>KLF4</i> mutations predominantly in low-grade regions.Gut2021
32228266Integrated Informatics Analysis of Cancer-Related Variants.JCO Clin Cancer Inform2020
32075918Assessing aneuploidy with repetitive element sequencing.Proc Natl Acad Sci U S A2020
32228266Integrated Informatics Analysis of Cancer-Related Variants.JCO Clin Cancer Inform2020
32984843Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer.Nat Cancer2020
33294860Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma.Cell Rep Med2020
32075918Assessing aneuploidy with repetitive element sequencing.Proc Natl Acad Sci U S A2020
33294860Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma.Cell Rep Med2020
32984843Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer.Nat Cancer2020
30430578Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.J Pathol2019
31780749Characterization of genetic subclonal evolution in pancreatic cancer mouse models.Nat Commun2019
31562479Voices in methods development.Nat Methods2019
30541742Dynamics of Tumor and Immune Responses during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.Cancer Res2019
30430578Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.J Pathol2019
31301157Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants.Hum Mutat2019
31175866Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.Gastroenterology2019
31202631CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers.Cell Syst2019
31316009A multimodality test to guide the management of patients with a pancreatic cyst.Sci Transl Med2019
31780749Characterization of genetic subclonal evolution in pancreatic cancer mouse models.Nat Commun2019
31562479Voices in methods development.Nat Methods2019
31301157Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants.Hum Mutat2019
31175866Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.Gastroenterology2019
31316009A multimodality test to guide the management of patients with a pancreatic cyst.Sci Transl Med2019
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Collaborators

Hannah Carter
University of California San Diego
Co-authored papers 21
Bert Vogelstein
Co-authored papers 21
Kenneth W Kinzler
Co-authored papers 21
Victor E Velculescu
Co-authored papers 18
Nickolas Papadopoulos
Co-authored papers 18
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 9
Siân Jones
Co-authored papers 8
Mark Diekhans
Genomics Institute, University of California Santa Cruz
Co-authored papers 8
Sean D Mooney
University of Washington
Co-authored papers 7
Michael Ryan
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Libusha Kelly
Albert Einstein College of Medicine
Co-authored papers 6
David N Cooper
Institute of Medical Genetics, Cardiff University
Co-authored papers 6
Peter D Stenson
Co-authored papers 6
Alvaro N A Monteiro
H. Lee Moffitt Cancer Center & Research Institute
Co-authored papers 6
Giovanni Parmigiani
Dana Farber Cancer Institute.
Co-authored papers 6
Melissa S Cline
Genomics Institute, University of California Santa Cruz
Co-authored papers 6
Steven E Brenner
University of California berkeley
Co-authored papers 5
Garry R Cutting
Johns Hopkins University School of Medicine
Co-authored papers 5
Fernando S Goes
Johns Hopkins University School of Medicine
Co-authored papers 5
James B Potash
University Hospital Frankfurt
Co-authored papers 5
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 4
Rebecca J Leary
Co-authored papers 4
Donald W Parsons
Texas Children's Hospital
Co-authored papers 4
Yuri Nikolsky
Co-authored papers 4
James Hartigan
Co-authored papers 4
Xiaosong Zhang
Co-authored papers 4
Douglas R Smith
Co-authored papers 4
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 4
Jianjiong Gao
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Han Liang
MD Anderson Cancer Center
Co-authored papers 4
Release 1.2