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Author Details

Yoko Kosaka
Oregon Health & Science University
1984
23
17
PMIDPaper TitleJournal TitlePublished Year
36681742BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8<sup>+</sup> T cells.Leukemia2023
37781631Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency.bioRxiv2023
37199721Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases.Clin Cancer Res2023
35868306Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.Cancer Cell2022
32898857Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph+ ALL.Blood2021
32513686Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.Proc Natl Acad Sci U S A2020
31122145Differential Immunomodulatory Effects of Human Bone Marrow-Derived Mesenchymal Stromal Cells on Natural Killer Cells.Stem Cells Dev2019
31648326Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway.Blood Adv2019
22271890Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model.Haematologica2012
21304898Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model.PLoS One2011
21314241Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells.Cytotherapy2011
19416854Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo.Proc Natl Acad Sci U S A2009
18566401Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens.J Immunol2008
17383541Tec kinases in T cell and mast cell signaling.Adv Immunol2007
16931156Itk and Th2 responses: action but no reaction.Trends Immunol2006
10533319CD40-CD154 interactions in B-cell signaling.Curr Top Microbiol Immunol2000
10637282Lineage-restricted function of nuclear factor kappaB-inducing kinase (NIK) in transducing signals via CD40.J Exp Med2000
10229103Activation and regulation of the IkappaB kinase in human B cells by CD40 signaling.Eur J Immunol1999
9714801Detection of nivalenol genotoxicity in cultured cells and multiple mouse organs by the alkaline single-cell gel electrophoresis assay.Mutat Res1998
9711263Detection of pyrimethamine-induced DNA damage in mouse embryo and maternal organs by the modified alkaline single cell gel electrophoresis assay.Mutat Res1998
9221764Assembly and regulation of the CD40 receptor complex in human B cells.J Exp Med1997
2442981Oxatomide inhibits the release of bronchoconstrictor arachidonic acid metabolites (iLTC4 and PGD2) from rat mast cells and guinea-pig lung.Agents Actions1987
6466397Large cystic lesions of the upper lobes of the lungs in two patients with CHEST syndrome.Arthritis Rheum1984
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Collaborators

Oregon Health & Science University
Co-authored papers 8
Oregon Health & Science University
Co-authored papers 4
Oregon Health & Science University, University of California Berkeley
Co-authored papers 3
Oregon Health & Science University School of Medicine
Co-authored papers 3
Medical College of Wisconsin
Co-authored papers 3
Oregon Health and Science University
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 2
Seattle Children's Hospital, University of Washington
Co-authored papers 2
St Jude Children's Research Hospital.
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Oregon Health & Science University, Knight Cancer Institute
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Northeastern University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Astex Pharmaceuticals
Co-authored papers 1