Author details

Full Name

Ivan Rusyn

Affiliation

ORCID

Career Start Year

1998

Papers

303

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503163	Ten Years of Using Key Characteristics of Human Carcinogens to Organize and Evaluate Mechanistic Evidence in IARC Monographs on the Identification of Carcinogenic Hazards to Humans: Patterns and Associations.		2023
37577363	Air Pollutant Patterns and Human Health Risk following the East Palestine, Ohio, Train Derailment.		2023
37555834	Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity.		2023
36907393	Imidacloprid exposure is detectable in over one third of wild bird samples from diverse Texas ecoregions.		2023
36765087	Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.	Nat Commun	2023
37079747	A tiered testing strategy based on in vitro phenotypic and transcriptomic data for selecting representative petroleum UVCBs for toxicity evaluation in vivo.		2023
36625475	Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice.		2023
36473579	Analytical chemistry solutions to hazard evaluation of petroleum refining products.	Regulatory Toxicology and Pharmacology	2023
37243727	Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood lead levels using the Collaborative Cross mouse population.	Toxicol Sci	2023
37530422	Application of Ion Mobility Spectrometry-Mass Spectrometry for Compositional Characterization and Fingerprinting of a Library of Diverse Crude Oil Samples.		2023
37505552	Integrative Chemical-Biological Grouping of Complex High Production Volume Substances from Lower Olefin Manufacturing Streams.		2023
35324388	Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet.	Epigenetics	2022
35908049	Novel adult cortical neuron processing and screening method illustrates sex- and age-dependent effects of pharmaceutical compounds.	Scientific Reports	2022
36287846	Evaluation of Metabolism of a Defined Pesticide Mixture through Multiple In Vitro Liver Models.	Toxics	2022
36287830	Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex Mixture Exposures in a Population-Based Human In Vitro Model.	Toxics	2022
35636685	Model systems and organisms for addressing inter- and intra-species variability in risk assessment.	Regulatory Toxicology and Pharmacology	2022
36006120	A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures.	Toxics	2022
35690411	Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review.	Mutation Research - Reviews in Mutation Research	2022
35689632	Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium.	Toxicological Sciences	2022
35621199	Integrating nonlinear analysis and machine learning for human induced pluripotent stem cell-based drug cardiotoxicity testing.	Journal of Tissue Engineering and Regenerative Medicine	2022
35357501	A Model of Human Small Airway on a Chip for Studies of Subacute Effects of Inhalation Toxicants.	Toxicological Sciences	2022
36057418	Analysis of reproducibility and robustness of OrganoPlateÂ® 2-lane 96, a liver microphysiological system for studies of pharmacokinetics and toxicological assessment of drugs.	Toxicology in Vitro	2022
35858665	Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice.	Journal of Nutritional Biochemistry	2022
35605020	Oil Irradiation Experiments Document Changes in Oil Properties, Molecular Composition, and Dispersant Effectiveness Associated with Oil Photo-Oxidation.	Environmental Science & Technology	2022
35469930	Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice.	Regulatory Toxicology and Pharmacology	2022
35404442	Decision-Making with New Approach Methodologies: Time to Replace Default Uncertainty Factors with Data.	Toxicological Sciences	2022
36413931	Temporal chemical composition changes in water below a crude oil slick irradiated with natural sunlight.	Marine Pollution Bulletin	2022
36445294	Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver Models to Improve Precision in Risk Characterization.	Environmental Health Perspectives	2022
36668745	Dosing Methods to Enable Cell-Based In Vitro Testing of Complex Substances: A Case Study with a PAH Mixture.		2022
35288757	Grouping of UVCB substances with dose-response transcriptomics data from human cell-based assays.	ALTEX	2022
34391970	Molecular mechanisms of environmental toxin cadmium at the feto-maternal interface investigated using an organ-on-chip (FMi-OOC) model.		2022
35250041	Characterization of Compositional Variability in Petroleum Substances.	Fuel	2022
34668045	Utilizing ion mobility spectrometry-mass spectrometry for the characterization and detection of persistent organic pollutants and their metabolites.	Anal Bioanal Chem	2022
34969462	Analysis of per- and polyfluoroalkyl substances in Houston Ship Channel and Galveston Bay following a large-scale industrial fire using ion-mobility-spectrometry-mass spectrometry.	J Environ Sci (China)	2022
34783606	Emerging technologies and their impact on regulatory science.	Exp Biol Med (Maywood)	2022
35162780	Spatial and Temporal Analysis of Impacts of Hurricane Florence on Criteria Air Pollutants and Air Toxics in Eastern North Carolina.	International Journal of Environmental Research and Public Health	2022
34999233	A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability.		2022
34366560	Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry.	Energy Fuels	2021
34081146	Species Differences between Mouse and Human PPARÎ± in Modulating the Hepatocarcinogenic Effects of Perinatal Exposure to a High-Affinity Human PPARÎ± Agonist in Mice.	Toxicological Sciences	2021
34081128	Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARÎ± Agonist in PPARA-Humanized Mice.	Toxicological Sciences	2021
34079063	Spatial and temporal distribution of surface water contaminants in the Houston Ship Channel after the Intercontinental Terminal Company Fire.	Journal of Exposure Science and Environmental Epidemiology	2021
33484733	Editorial overview of the special issue on application of tissue chips in toxicology.	Toxicology	2021
34233495	Curated Data In - Trustworthy <i>In Silico</i> Models Out: The Impact of Data Quality on the Reliability of Artificial Intelligence Models as Alternatives to Animal Testing.	Altern Lab Anim	2021
33895777	Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks.	Journal of Exposure Science and Environmental Epidemiology	2021
34105804	Key Characteristics of Human Hepatotoxicants as a Basis for Identification and Characterization of the Causes of Liver Toxicity.	Hepatology	2021
33612039	Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization.		2021
33988684	Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice.	Toxicological Sciences	2021
33450301	Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes.	Food Chem Toxicol	2021
34142158	Quantitative In Vitro-to-In Vivo Extrapolation for Mixtures: A Case Study of Superfund Priority List Pesticides.	Toxicological Sciences	2021
33315271	A Comparative Analysis of Analytical Techniques for Rapid Oil Spill Identification.	Environ Toxicol Chem	2021