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Author Details
Full Name
Dieter Weichenhan
Affiliation
German Cancer Research Center (DKFZ)
ORCID
Career Start Year
1988
Papers
127
H Index
39
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36632736
TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.
Haematologica
2023
37885041
Predictive value of DNA methylation patterns in AML patients treated with an azacytidine containing induction regimen.
Clin Epigenetics
2023
36949154
Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking.
Leukemia
2023
37143403
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD.
EMBO J
2023
36402192
Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression.
Gastroenterology
2023
36939901
Indirect epigenetic testing identifies a diagnostic signature of cardiomyocyte DNA methylation in heart failure.
Basic Res Cardiol
2023
36704932
Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions.
Allergy
2023
32822861
Epigenomic technologies for precision oncology.
Semin Cancer Biol
2022
35468210
MEOX2 homeobox gene promotes growth of malignant gliomas.
Neuro Oncol
2022
36070377
Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function.
Sci Adv
2022
35931677
Club cells employ regeneration mechanisms during lung tumorigenesis.
Nat Commun
2022
36026441
Transcriptional regulation of the thymus master regulator <i>Foxn1</i>.
Sci Immunol
2022
36287637
Global DNA Methylation Analysis of Cancer-Associated Fibroblasts Reveals Extensive Epigenetic Rewiring Linked with RUNX1 Upregulation in Breast Cancer Stroma.
Cancer Res
2022
35247900
Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma.
Blood Cancer Discov
2022
35239184
Selective inhibitors of bromodomain BD1 and BD2 of BET proteins modulate radiation-induced profibrotic fibroblast responses.
Int J Cancer
2022
33468537
Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.
Gut
2022
33203699
Decitabine Induces Gene Derepression on Monosomic Chromosomes: <i>In Vitro</i> and <i>In Vivo</i> Effects in Adverse-Risk Cytogenetics AML.
Cancer Res
2021
34764283
Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease.
Nat Commun
2021
34718742
ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.
Nucleic Acids Res
2021
34070078
Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response.
Cancers (Basel)
2021
34098582
MicroRNA-497/195 is tumor suppressive and cooperates with CDKN2A/B in pediatric acute lymphoblastic leukemia.
Blood
2021
33197445
Diabetes changes gene expression but not DNA methylation in cardiac cells.
J Mol Cell Cardiol
2021
33060108
Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin.
Cancer Discov
2021
33100132
AmpliconDesign - an interactive web server for the design of high-throughput targeted DNA methylation assays.
Epigenetics
2021
32272161
Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.
J Thorac Oncol
2020
31871210
Identification of Ppar<i>γ</i>-modulated miRNA hubs that target the fibrotic tumor microenvironment.
Proc Natl Acad Sci U S A
2020
32005851
Neuronal ensemble-specific DNA methylation strengthens engram stability.
Nat Commun
2020
33110075
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Nat Commun
2020
30615206
Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.
Hepatology
2019
30171030
Fetal hemoglobin induction during decitabine treatment of elderly patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: a potential dynamic biomarker of outcome.
Haematologica
2019
30779037
Generation of Whole Genome Bisulfite Sequencing Libraries from Very Low DNA Input.
Methods Mol Biol
2019
31012487
Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze.
Allergy
2019
31064978
DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis.
Nat Commun
2019
31135957
Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer.
Int J Cancer
2019
30962454
Rbpj expression in regulatory T cells is critical for restraining T<sub>H</sub>2 responses.
Nat Commun
2019
30664630
Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands.
Nat Commun
2019
28921505
NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.
Int J Cancer
2018
30537516
Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.
Cancer Cell
2018
28392331
Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.
J Allergy Clin Immunol
2018
29749927
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.
Elife
2018
29633898
Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors.
Cell Cycle
2018
29374152
Distinct epigenetic programs regulate cardiac myocyte development and disease in the human heart in vivo.
Nat Commun
2018
29233739
Early-onset childhood atopic dermatitis is related to NLRP2 repression.
J Allergy Clin Immunol
2018
29224141
Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing.
Methods Mol Biol
2018
28838933
Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.
Circulation
2017
28100914
TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation.
Int J Obes (Lond)
2017
28344890
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.
Oncoimmunology
2017
29074949
Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Nat Genet
2017
29144491
Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Nat Immunol
2017
28783152
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Nat Immunol
2017
1 - 50 of 127
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Berlin Institute of Health (BIH) and Charite
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Catholic University (KU) Leuven
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10
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University of Augsburg
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9
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Co-authored papers
8
Saskia Trump
Berlin Institute of Health at Charite - Universitatsmedizin Berlin
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8
Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
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7
Michael Rehli
University Hospital Regensburg
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7
Clarissa Gerh??user
German Cancer Research Center (DKFZ)
Co-authored papers
6
Olga Bogatyrova
German Cancer Research Center
Co-authored papers
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Peter Lichter
German Cancer Research Center (DKFZ)
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5
Chris Lawerenz
German Cancer Research Center (DKFZ)
Co-authored papers
4
Stefan Wiemann
Co-authored papers
3
Stephanie Roessler
Institute of Pathology, University Hospital Heidelberg
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3
Walter J Koch
Co-authored papers
3
Stephan Wolf
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3
Holger S??ltmann
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3
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