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Author Details
Full Name
Greg Lemke
Affiliation
Salk Institute for Biological Studies
ORCID
Career Start Year
1980
Papers
148
H Index
77
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37673933
Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer.
Commun Biol
2023
37572655
CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma.
Immunity
2023
36191221
Early death in a mouse model of Alzheimer's disease exacerbated by microglial loss of TAM receptor signaling.
Proc Natl Acad Sci U S A
2022
35731195
The dense-core plaques of Alzheimer's disease are granulomas.
J Exp Med
2022
36472212
Adaptable toolbox to characterize Alzheimer's disease pathology in mouse models.
STAR Protoc
2022
35967387
The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages.
Front Immunol
2022
36327895
Microglia states and nomenclature: A field at its crossroads.
Neuron
2022
33859405
Microglia use TAM receptors to detect and engulf amyloid β plaques.
Nat Immunol
2021
32488201
Blood clots and TAM receptor signalling in COVID-19 pathogenesis.
Nat Rev Immunol
2020
31896673
Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome.
J Neurosci
2020
32937105
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
Cell
2020
32571802
Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer.
Life Sci Alliance
2020
31019284
How macrophages deal with death.
Nat Rev Immunol
2019
30980657
TAM receptors in cardiovascular disease.
Cardiovasc Res
2019
28734578
Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands.
Trends Biochem Sci
2017
28111081
Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.
Neuron
2017
28322188
A molecular mechanism for the topographic alignment of convergent neural maps.
Elife
2017
28639625
MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis.
Nat Commun
2017
27049947
TAM receptors regulate multiple features of microglial physiology.
Nature
2016
25605971
A ligand for ALK.
Sci Signal
2015
26676577
Adopting ALK and LTK.
Proc Natl Acad Sci U S A
2015
26523970
The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity.
Nat Med
2015
26140597
Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation.
Cell
2015
25695599
Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells.
Cell Death Dis
2015
25194421
Diversification of TAM receptor tyrosine kinase function.
Nat Immunol
2014
25265470
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Elife
2014
25258411
Stephen F. Heinemann: A true original.
Proc Natl Acad Sci U S A
2014
23325690
Is the TAM receptor Axl a receptor for lymphocytic choriomeningitis virus?
J Virol
2013
24186067
Biology of the TAM receptors.
Cold Spring Harb Perspect Biol
2013
23850380
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Immunity
2013
23954153
Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors.
Cell Host Microbe
2013
22095910
VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: the first description of a VAX1 phenotype in humans.
Hum Mutat
2012
23259948
Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.
Neuron
2012
23084921
The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry.
Cell Host Microbe
2012
23071254
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.
J Exp Med
2012
21753007
Genetic dissection of EphA receptor signaling dynamics during retinotopic mapping.
J Neurosci
2011
22157225
Dominant-negative isoforms of Tcf/Lef proteins in development and disease.
Cell Cycle
2011
21805534
Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy.
Stem Cells
2011
21856776
A novel mechanism for the transcriptional regulation of Wnt signaling in development.
Genes Dev
2011
21030229
TAM receptor signaling and autoimmune disease.
Curr Opin Immunol
2010
20958312
TAM receptors and the clearance of apoptotic cells.
Ann N Y Acad Sci
2010
19501646
Disturbed distribution of proliferative brain cells during lupus-like disease.
Brain Behav Immun
2009
19729839
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.
J Clin Invest
2009
19804762
Retinal input instructs alignment of visual topographic maps.
Cell
2009
19380252
The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration.
Trends Mol Med
2009
18188450
Role of Gas6 in erythropoiesis and anemia in mice.
J Clin Invest
2008
18787040
Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration.
Mol Endocrinol
2008
18997061
Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium.
Genes Dev
2008
18995810
Isolation and analysis of the gene encoding peripheral myelin protein zero.
Neuron
2008
18403711
Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling.
Science
2008
1 - 50 of 148
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