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Author Details

Karl Frei
University Hospital Zurich
1982
145
63
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36917178Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature.JCI Insight2023
35641277Republication: Targeting PI3KC2β Impairs Proliferation and Survival in Acute Leukemia, Brain Tumours and Neuroendocrine Tumours.Anticancer Res2022
30290761Tunneling nanotubes evoke pericyte/endothelial communication during normal and tumoral angiogenesis.Fluids Barriers CNS2018
29029628Erythropoietin reduces experimental autoimmune encephalomyelitis severity via neuroprotective mechanisms.J Neuroinflammation2017
29152068Age-associated and therapy-induced alterations in the cellular microenvironment of experimental gliomas.Oncotarget2017
27347163Interleukin-33 in human gliomas: Expression and prognostic significance.Oncol Lett2016
25849941Transforming growth factor-β pathway activity in glioblastoma.Oncotarget2015
26182414Wiring the Vascular Network with Neural Cues: A CNS Perspective.Neuron2015
26090865Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition.Oncotarget2015
24355709Thymosin β 4 gene silencing decreases stemness and invasiveness in glioblastoma.Brain2014
25289892How stemlike are sphere cultures from long-term cancer cell lines? Lessons from mouse glioma models.J Neuropathol Exp Neurol2014
25014440Bleeding propensity of cavernous malformations: impact of tight junction alterations on the occurrence of overt hematoma.J Neurosurg2014
25175943Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (review).Int J Oncol2014
24526161Interferon-β induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells.Mol Cancer Ther2014
24718026Targeting class IA PI3K isoforms selectively impairs cell growth, survival, and migration in glioblastoma.PLoS One2014
23360820Soluble α-klotho: a novel serum biomarker for the activity of GH-producing pituitary adenomas.Eur J Endocrinol2013
24386429Diversified expression of NG2/CSPG4 isoforms in glioblastoma and human foetal brain identifies pericyte subsets.PLoS One2013
23625008Nogo-A is a negative regulator of CNS angiogenesis.Proc Natl Acad Sci U S A2013
23344887The CXCL12/CXCR4/CXCR7 ligand-receptor system regulates neuro-glio-vascular interactions and vessel growth during human brain development.J Inherit Metab Dis2013
22843869Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours.Anticancer Res2012
23177320Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia.Immunity2012
23146900Expression of nogo-a is decreased with increasing gestational age in the human fetal brain.Dev Neurosci2012
22688083Patupilone (epothilone B) for recurrent glioblastoma: clinical outcome and translational analysis of a single-institution phase I/II trial.Oncology2012
22909291Proteomic analysis reveals drug accessible cell surface N-glycoproteins of primary and established glioblastoma cell lines.J Proteome Res2012
21471286Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial.Mol Cancer Ther2011
22937234Characterization of the gene expression profile of human hippocampus in mesial temporal lobe epilepsy with hippocampal sclerosis.Epilepsy Res Treat2011
21572340Impairment of tight junctions and glucose transport in endothelial cells of human cerebral cavernous malformations.J Neuropathol Exp Neurol2011
21743064The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells.Neuro Oncol2011
21757006Adoptive transfer of T lymphocytes in immunodeficient mice influences epileptogenesis and neurodegeneration in a model of temporal lobe epilepsy.Neurobiol Dis2011
21411646Brain infiltration of leukocytes contributes to the pathophysiology of temporal lobe epilepsy.J Neurosci2011
18489490EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas.Brain Pathol2009
19337997Site-specific anti-tumor immunity: differences in DC function, TGF-beta production and numbers of intratumoral Foxp3+ Treg.Eur J Immunol2009
19066471The antibacterial substance taurolidine exhibits anti-neoplastic action based on a mixed type of programmed cell death.Autophagy2009
18091560Fetal blood-brain barrier P-glycoprotein contributes to brain protection during human development.J Neuropathol Exp Neurol2008
18580350Combined therapeutic hypothermia and barbiturate coma reduces interleukin-6 in the cerebrospinal fluid after aneurysmal subarachnoid hemorrhage.J Neurosurg Anesthesiol2008
18431253Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins.J Neuropathol Exp Neurol2008
17008949Gefitinib concentrations in human glioblastoma tissue.J Neurooncol2007
16361082Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis.Epilepsy Res2006
17015303Magnetic iron compounds in the human brain: a comparison of tumour and hippocampal tissue.J R Soc Interface2006
16582594Gefitinib accumulation in glioblastoma tissue.Cancer Biol Ther2006
15781448Effects of protein and gene transfer of the angiopoietin-1 fibrinogen-like receptor-binding domain on endothelial and vessel organization.J Biol Chem2005
15941778CD14 deficiency leads to increased MIP-2 production, CXCR2 expression, neutrophil transmigration, and early death in pneumococcal infection.J Leukoc Biol2005
16028765Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.J Neurosurg2005
15113693Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme.Anal Biochem2004
12783272Genes and pathways driving glioblastomas in humans and murine disease models.Neurosurg Rev2003
14603463TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes.Glia2003
11888694HSV-1-based amplicon particles are able to transduce cells of feline origin with genes encoding biologically functional feline IL-10 or IL-6.Vet Microbiol2002
12198614Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.J Infect Dis2002
12137564Extracellular signal-regulated protein kinase activation during reoxygenation is required to restore ischaemia-induced endothelial barrier failure.Biochem J2002
12084561Evaluation of brain toxicity following near infrared light exposure after indocyanine green dye injection.J Neurosci Methods2002
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Collaborators

Michael Weller
University Hospital and University of Zurich
Co-authored papers 12
Hans Lassmann
Co-authored papers 7
David Leppert
Biomedicine and Clinical Research, University Hospital Basel, University of Basel
Co-authored papers 5
Elisabeth J Rushing
Co-authored papers 4
Heinz Gregor Wieser
University of ZurichZurichSwitzerland.
Co-authored papers 3
Guido Reifenberger
Heinrich Heine University
Co-authored papers 3
Michael A Grotzer
University Children's Hospital
Co-authored papers 3
Ghazaleh Tabatabai
University Hospital Tubingen, Eberhard-Karls-University Tubingen
Co-authored papers 3
Erwin G Van Meir
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 2
Marin Marinov
Co-authored papers 2
Kalpoondi Sekar Rajan
Weizmann Institute of Science
Co-authored papers 2
Johannes Haybaeck
Institute of Pathology, Medical University of Innsbruck
Co-authored papers 2
André O von Bueren
Co-authored papers 2
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 2
Silvia Dolski
University Hospital Zurich
Co-authored papers 2
Andreas Hofmann
Heidelberg University
Co-authored papers 1
Thomas Bock
University of Basel
Co-authored papers 1
Bernd Wollscheid
ETH Zurich
Co-authored papers 1
Jeffrey P Greenfield
Weill Cornell Medical Center, NewYork Presbyterian Hospital
Co-authored papers 1
Melanie Greter
Co-authored papers 1
Katerina Akassoglou
Gladstone Institute for Neurological Disease San Francisco
Co-authored papers 1
Niklaus Krayenbuehl
Clinical Neuroscience Center, University Hospital and University of Zurich
Co-authored papers 1
Frank L Heppner
Co-authored papers 1
Andrea Jacobs
University of Zurich
Co-authored papers 1
Stefan Rutkowski
University Medical Center Hamburg-Eppendorf
Co-authored papers 1
Miriam Merad
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
David Capper
Charite University Medicine Berlin
Co-authored papers 1
Kai St??hler
Universitatsklinikum
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Hansjoerg Moest
Institute of Food, ETH Zurich
Co-authored papers 1
Release 1.2